Retinal Distribution and Extracellular Activity of Granzyme B: A Serine Protease That Degrades Retinal Pigment Epithelial Tight Junctions and Extracellular Matrix Proteins

by Joanne A. Matsubara, Yuan Tian, Jing Z. Cui, Matthew R. Zeglinski, Matthew R. Zeglinski, Sho Hiroyasu, Sho Hiroyasu, Christopher T. Turner, Christopher T. Turner, David J. Granville, David J. Granville
Published 2020-04-01

Granzyme B mediates impaired healing of pressure injuries in aged skin

by Christopher T. Turner, Juliana Bolsoni, Matthew R. Zeglinski, Hongyan Zhao, Tatjana Ponomarev, Katlyn Richardson, Sho Hiroyasu, Erin Schmid, Anthony Papp, David J. Granville
Published 2021-03-01

Soluble Wood Smoke Extract Promotes Barrier Dysfunction in Alveolar Epithelial Cells through a MAPK Signaling Pathway

by Matthew R. Zeglinski, Christopher T. Turner, Rui Zeng, Carley Schwartz, Stephanie Santacruz, Megan A. Pawluk, Hongyan Zhao, Arthur W. H. Chan, Christopher Carlsten, David J. Granville
Published 2019-07-01

Granzyme B inhibition reduces disease severity in autoimmune blistering diseases

by Sho Hiroyasu, Matthew R. Zeglinski, Hongyan Zhao, Megan A. Pawluk, Christopher T. Turner, Anika Kasprick, Chiharu Tateishi, Wataru Nishie, Angela Burleigh, Peter A. Lennox, Nancy Van Laeken, Nick J. Carr, Frank Petersen, Richard I. Crawford, Hiroshi Shimizu, Daisuke Tsuruta, Ralf J. Ludwig, David J. Granville
Published 2021-01-01

Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

by Yue Shen, Matthew R. Zeglinski, Christopher T. Turner, Sheetal A. Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R. Cameron, Anthony Papp, David J. Granville
Published 2018-05-01