Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

by Jonathan Frew, Alireza Baradaran-Heravi, Aruna D. Balgi, Xiujuan Wu, Tyler D. Yan, Steve Arns, Fahimeh S. Shidmoossavee, Jason Tan, James B. Jaquith, Karen R. Jansen-West, Francis C. Lynn, Fen-Biao Gao, Leonard Petrucelli, Howard H. Feldman, Ian R. Mackenzie, Michel Roberge, Haakon B. Nygaard
Published 2020-03-01

Topical small molecule granzyme B inhibitor improves remodeling in a murine model of impaired burn wound healing

by Yue Shen, Matthew R. Zeglinski, Christopher T. Turner, Sheetal A. Raithatha, Zhenguo Wu, Valerio Russo, Cameron Oram, Sho Hiroyasu, Layla Nabai, Hongyan Zhao, Tatjana Bozin, Kathryn Westendorf, Irina Kopko, Rachel Huang, Steve Arns, Jason Tan, Haishan Zeng, Anthony Boey, Richard Liggins, James Jaquith, Dale R. Cameron, Anthony Papp, David J. Granville
Published 2018-05-01