A Novel Antagonist of the Immune Checkpoint Protein Adenosine A2a Receptor Restores Tumor-Infiltrating Lymphocyte Activity in the Context of the Tumor Microenvironment

by Melanie Mediavilla-Varela, Julio Castro, Alberto Chiappori, David Noyes, Dalia C. Hernandez, Bertrand Allard, John Stagg, Scott J. Antonia
Published 2017-07-01

Transforming growth factor β signaling overcomes dasatinib resistance in lung cancer.

by Edna Gordian, Jiannong Li, Yuri Pevzner, Melanie Mediavilla-Varela, Kimberly Luddy, Kim Ohaegbulam, Kenyon G Daniel, Eric B Haura, Teresita Muñoz-Antonia
Published 2014-01-01

HDAC6 Inhibition Alleviates CLL-Induced T-Cell Dysfunction and Enhances Immune Checkpoint Blockade Efficacy in the Eμ-TCL1 Model

by Kamira Maharaj, Kamira Maharaj, John J. Powers, Melanie Mediavilla-Varela, Alex Achille, Wael Gamal, Wael Gamal, Steven Quayle, Simon S. Jones, Eva Sahakian, Eva Sahakian, Javier Pinilla-Ibarz, Javier Pinilla-Ibarz
Published 2020-11-01

LEDGF/p75 Overexpression Attenuates Oxidative Stress-Induced Necrosis and Upregulates the Oxidoreductase ERP57/PDIA3/GRP58 in Prostate Cancer.

by Anamika Basu, Christina K Cajigas-Du Ross, Leslimar Rios-Colon, Melanie Mediavilla-Varela, Tracy R Daniels-Wells, Lai Sum Leoh, Heather Rojas, Hiya Banerjee, Shannalee R Martinez, Stephanny Acevedo-Martinez, Carlos A Casiano
Published 2016-01-01