AAV vectors engineered to target insulin receptor greatly enhance intramuscular gene delivery

by Cody B. Jackson, Audrey S. Richard, Amrita Ojha, Kimberly A. Conkright, Jeffrey M. Trimarchi, Charles C. Bailey, Michael D. Alpert, Mark A. Kay, Michael Farzan, Hyeryun Choe
Published 2020-12-01

ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.

by Michael D Alpert, Jackson D Harvey, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans
Published 2012-01-01

Mutations derived from horseshoe bat ACE2 orthologs enhance ACE2-Fc neutralization of SARS-CoV-2.

by Huihui Mou, Brian D Quinlan, Haiyong Peng, Guanqun Liu, Yan Guo, Shoujiao Peng, Lizhou Zhang, Meredith E Davis-Gardner, Matthew R Gardner, Gogce Crynen, Lindsey B DeVaux, Zhi Xiang Voo, Charles C Bailey, Michael D Alpert, Christoph Rader, Michaela U Gack, Hyeryun Choe, Michael Farzan
Published 2021-04-01