Rhesus monkey rhadinovirus uses eph family receptors for entry into B cells and endothelial cells but not fibroblasts.

by Alexander S Hahn, Ronald C Desrosiers
Published 2013-01-01

Promise and problems associated with the use of recombinant AAV for the delivery of anti-HIV antibodies

by Sebastian P Fuchs, Ronald C Desrosiers
Published 2016-01-01

Systematic analysis of intracellular trafficking motifs located within the cytoplasmic domain of simian immunodeficiency virus glycoprotein gp41.

by Thomas S Postler, Jacqueline G Bixby, Ronald C Desrosiers, Eloísa Yuste
Published 2014-01-01

Recombinant AAV Vectors for Enhanced Expression of Authentic IgG.

by Sebastian P Fuchs, José M Martinez-Navio, Guangping Gao, Ronald C Desrosiers
Published 2016-01-01

Plxdc family members are novel receptors for the rhesus monkey rhadinovirus (RRV).

by Anna K Großkopf, Sarah Schlagowski, Thomas Fricke, Armin Ensser, Ronald C Desrosiers, Alexander S Hahn
Published 2021-03-01

Liver-Directed but Not Muscle-Directed AAV-Antibody Gene Transfer Limits Humoral Immune Responses in Rhesus Monkeys

by Sebastian P. Fuchs, José M. Martinez-Navio, Eva G. Rakasz, Guangping Gao, Ronald C. Desrosiers
Published 2020-03-01

Glycoengineering of AAV-delivered monoclonal antibodies yields increased ADCC activity

by James M. Termini, José M. Martinez-Navio, Guangping Gao, Sebastian P. Fuchs, Ronald C. Desrosiers
Published 2021-03-01

A conserved Eph family receptor-binding motif on the gH/gL complex of Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus.

by Anna K Großkopf, Armin Ensser, Frank Neipel, Doris Jungnickl, Sarah Schlagowski, Ronald C Desrosiers, Alexander S Hahn
Published 2018-02-01

AAV-Delivered Antibody Mediates Significant Protective Effects against SIVmac239 Challenge in the Absence of Neutralizing Activity.

by Sebastian P Fuchs, José M Martinez-Navio, Michael Piatak, Jeffrey D Lifson, Guangping Gao, Ronald C Desrosiers
Published 2015-08-01

Discovery of O-Linked Carbohydrate on HIV-1 Envelope and Its Role in Shielding against One Category of Broadly Neutralizing Antibodies

by Zachary A. Silver, Aristotelis Antonopoulos, Stuart M. Haslam, Anne Dell, Gordon M. Dickinson, Michael S. Seaman, Ronald C. Desrosiers
Published 2020-02-01

HEK293T cell lines defective for O-linked glycosylation.

by James M Termini, Zachary A Silver, Bryony Connor, Aristotelis Antonopoulos, Stuart M Haslam, Anne Dell, Ronald C Desrosiers
Published 2017-01-01

Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed.

by Xuezhong Cai, Alexandra Schäfer, Shihua Lu, John P Bilello, Ronald C Desrosiers, Rachel Edwards, Nancy Raab-Traub, Bryan R Cullen
Published 2006-03-01

Long-Term Delivery of an Anti-SIV Monoclonal Antibody With AAV

by José M. Martinez-Navio, Sebastian P. Fuchs, Desiree E. Mendes, Eva G. Rakasz, Guangping Gao, Jeffrey D. Lifson, Ronald C. Desrosiers
Published 2020-03-01

SIV vpx is essential for macrophage infection but not for development of AIDS.

by Susan V Westmoreland, A Peter Converse, Kasia Hrecka, Mollie Hurley, Heather Knight, Michael Piatak, Jeffrey Lifson, Keith G Mansfield, Jacek Skowronski, Ronald C Desrosiers
Published 2014-01-01

A recombinant herpesviral vector containing a near-full-length SIVmac239 genome produces SIV particles and elicits immune responses to all nine SIV gene products.

by Young C Shin, Georg F Bischof, William A Lauer, Lucas Gonzalez-Nieto, Eva G Rakasz, Gregory M Hendricks, David I Watkins, Mauricio A Martins, Ronald C Desrosiers
Published 2018-06-01

ADCC develops over time during persistent infection with live-attenuated SIV and is associated with complete protection against SIV(mac)251 challenge.

by Michael D Alpert, Jackson D Harvey, W Anderson Lauer, R Keith Reeves, Michael Piatak, Angela Carville, Keith G Mansfield, Jeffrey D Lifson, Wenjun Li, Ronald C Desrosiers, R Paul Johnson, David T Evans
Published 2012-01-01

Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate.

by Elizabeth Stansell, Maria Panico, Kevin Canis, Poh-Choo Pang, Laura Bouché, Daniel Binet, Michael-John O'Connor, Elena Chertova, Julian Bess, Jeffrey D Lifson, Stuart M Haslam, Howard R Morris, Ronald C Desrosiers, Anne Dell
Published 2015-01-01

Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection.

by Sama Adnan, R Keith Reeves, Jacqueline Gillis, Fay E Wong, Yi Yu, Jeremy V Camp, Qingsheng Li, Michelle Connole, Yuan Li, Michael Piatak, Jeffrey D Lifson, Wenjun Li, Brandon F Keele, Pamela A Kozlowski, Ronald C Desrosiers, Ashley T Haase, R Paul Johnson
Published 2016-12-01

Vaccine protection against rectal acquisition of SIVmac239 in rhesus macaques.

by Lucas Gonzalez-Nieto, Isabelle M Castro, Georg F Bischof, Young C Shin, Michael J Ricciardi, Varian K Bailey, Christine M Dang, Nuria Pedreño-Lopez, Diogo M Magnani, Keisuke Ejima, David B Allison, Hwi Min Gil, David T Evans, Eva G Rakasz, Jeffrey D Lifson, Ronald C Desrosiers, Mauricio A Martins
Published 2019-09-01

Vaccine-induced immune responses against both Gag and Env improve control of simian immunodeficiency virus replication in rectally challenged rhesus macaques.

by Mauricio A Martins, Young C Shin, Lucas Gonzalez-Nieto, Aline Domingues, Martin J Gutman, Helen S Maxwell, Iris Castro, Diogo M Magnani, Michael Ricciardi, Nuria Pedreño-Lopez, Varian Bailey, Dillon Betancourt, John D Altman, Matthias Pauthner, Dennis R Burton, Benjamin von Bredow, David T Evans, Maoli Yuan, Christopher L Parks, Keisuke Ejima, David B Allison, Eva Rakasz, Glen N Barber, Saverio Capuano, Jeffrey D Lifson, Ronald C Desrosiers, David I Watkins
Published 2017-07-01