PALI1 facilitates DNA and nucleosome binding by PRC2 and triggers an allosteric activation of catalysis

by Qi Zhang, Samuel C. Agius, Sarena F. Flanigan, Michael Uckelmann, Vitalina Levina, Brady M. Owen, Chen Davidovich
Published 2021-07-01

USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A

by Michael Uckelmann, Ruth M. Densham, Roy Baas, Herrie H. K. Winterwerp, Alexander Fish, Titia K. Sixma, Joanna R. Morris
Published 2018-01-01

Structural basis of specific H2A K13/K15 ubiquitination by RNF168

by Velten Horn, Michael Uckelmann, Heyi Zhang, Jelmer Eerland, Ivette Aarsman, Ulric B. le Paige, Chen Davidovich, Titia K. Sixma, Hugo van Ingen
Published 2019-04-01

Strategy for Development of Site-Specific Ubiquitin Antibodies

by Ila van Kruijsbergen, Monique P. C. Mulder, Michael Uckelmann, Tibor van Welsem, John de Widt, Aldo Spanjaard, Heinz Jacobs, Farid El Oualid, Huib Ovaa, Fred van Leeuwen, Fred van Leeuwen
Published 2020-02-01