Mimicking the Nucleosomal Context in Peptide-Based Binders of a H3K36me Reader Increases Binding Affinity While Altering the Binding Mode

by Velten Horn, Seino A. K. Jongkees, Hugo van Ingen
Published 2020-10-01

Structure and function of archaeal histones.

by Bram Henneman, Clara van Emmerik, Hugo van Ingen, Remus T Dame
Published 2018-09-01

Structural basis of specific H2A K13/K15 ubiquitination by RNF168

by Velten Horn, Michael Uckelmann, Heyi Zhang, Jelmer Eerland, Ivette Aarsman, Ulric B. le Paige, Chen Davidovich, Titia K. Sixma, Hugo van Ingen
Published 2019-04-01

Nucleosome binding peptide presents laudable biophysical and in vivo effects

by Kaian Teles, Vinicius Fernandes, Isabel Silva, Manuela Leite, Cesar Grisolia, Vincenzo R. Lobbia, Hugo van Ingen, Rodrigo Honorato, Paulo Lopes-de-Oliveira, Werner Treptow, Guilherme Santos
Published 2020-01-01

Corrigendum to “Nucleosome binding peptide presents laudable biophysical and in vivo effects” [Biomed. Pharmacother. 121 (2020) 109678]

by Kaian Teles, Vinicius Fernandes, Isabel Silva, Manuela Leite, Cesar Grisolia, Vincenzo R. Lobbia, Hugo van Ingen, Rodrigo Honorato, Paulo Lopes-de-Oliveira, Werner Treptow, Guilherme Santos
Published 2020-03-01

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity

by Robbert Q. Kim, Paul P. Geurink, Monique P. C. Mulder, Alexander Fish, Reggy Ekkebus, Farid El Oualid, Willem J. van Dijk, Duco van Dalen, Huib Ovaa, Hugo van Ingen, Titia K. Sixma
Published 2019-01-01

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

by Julianne Kitevski-LeBlanc, Amélie Fradet-Turcotte, Predrag Kukic, Marcus D Wilson, Guillem Portella, Tairan Yuwen, Stephanie Panier, Shili Duan, Marella D Canny, Hugo van Ingen, Cheryl H Arrowsmith, John L Rubinstein, Michele Vendruscolo, Daniel Durocher, Lewis E Kay
Published 2017-04-01