Modulation of the Interactions Between α-Synuclein and Lipid Membranes by Post-translational Modifications

by Rosie Bell, Michele Vendruscolo
Published 2021-07-01

A condensation-ordering mechanism in nanoparticle-catalyzed peptide aggregation.

by Stefan Auer, Antonio Trovato, Michele Vendruscolo
Published 2009-08-01

A Cell- and Tissue-Specific Weakness of the Protein Homeostasis System Underlies Brain Vulnerability to Protein Aggregation

by Rishika Kundra, Christopher M. Dobson, Michele Vendruscolo
Published 2020-03-01

A generic mechanism of emergence of amyloid protofilaments from disordered oligomeric aggregates.

by Stefan Auer, Filip Meersman, Christopher M Dobson, Michele Vendruscolo
Published 2008-11-01

A simple lattice model that captures protein folding, aggregation and amyloid formation.

by Sanne Abeln, Michele Vendruscolo, Christopher M Dobson, Daan Frenkel
Published 2014-01-01

Sequence-based prediction of protein binding mode landscapes.

by Attila Horvath, Marton Miskei, Viktor Ambrus, Michele Vendruscolo, Monika Fuxreiter
Published 2020-05-01

Rapid and accurate in silico solubility screening of a monoclonal antibody library

by Pietro Sormanni, Leanne Amery, Sofia Ekizoglou, Michele Vendruscolo, Bojana Popovic
Published 2017-08-01

Molecular dynamics ensemble refinement of the heterogeneous native state of NCBD using chemical shifts and NOEs

by Elena Papaleo, Carlo Camilloni, Kaare Teilum, Michele Vendruscolo, Kresten Lindorff-Larsen
Published 2018-07-01

Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures

by Tatsuya Ikenoue, Francesco A. Aprile, Francesco A. Aprile, Pietro Sormanni, Michele Vendruscolo
Published 2021-02-01

Structure of a low-population intermediate state in the release of an enzyme product

by Alfonso De Simone, Francesco A Aprile, Anne Dhulesia, Christopher M Dobson, Michele Vendruscolo
Published 2015-01-01

The molecular chaperones DNAJB6 and Hsp70 cooperate to suppress α-synuclein aggregation

by Francesco A. Aprile, Emma Källstig, Galina Limorenko, Michele Vendruscolo, David Ron, Christian Hansen
Published 2017-08-01

Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins

by Prajwal Ciryam, Gian Gaetano Tartaglia, Richard I. Morimoto, Christopher M. Dobson, Michele Vendruscolo
Published 2013-11-01

Nucleated Polymerisation in the Presence of Pre-Formed Seed Filaments

by Tuomas P. J. Knowles, Michele Vendruscolo, Samuel I. A. Cohen, Christopher M. Dobson
Published 2011-09-01

Single molecule secondary structure determination of proteins through infrared absorption nanospectroscopy

by Francesco Simone Ruggeri, Benedetta Mannini, Roman Schmid, Michele Vendruscolo, Tuomas P. J. Knowles
Published 2020-06-01

Expression of the amyloid-β peptide in a single pair of C. elegans sensory neurons modulates the associated behavioural response.

by Tessa Sinnige, Prashanth Ciryam, Samuel Casford, Christopher M Dobson, Mario de Bono, Michele Vendruscolo
Published 2019-01-01

Mapping the Protein Fold Universe Using the CamTube Force Field in Molecular Dynamics Simulations.

by Predrag Kukic, Arvind Kannan, Maurits J J Dijkstra, Sanne Abeln, Carlo Camilloni, Michele Vendruscolo
Published 2015-10-01

Prediction by graph theoretic measures of structural effects in proteins arising from non-synonymous single nucleotide polymorphisms.

by Tammy M K Cheng, Yu-En Lu, Michele Vendruscolo, Pietro Lio', Tom L Blundell
Published 2008-07-01

The Hsp70 Chaperone System Stabilizes a Thermo-sensitive Subproteome in E. coli

by Liang Zhao, Giulia Vecchi, Michele Vendruscolo, Roman Körner, Manajit Hayer-Hartl, F. Ulrich Hartl
Published 2019-07-01

Inversion of the balance between hydrophobic and hydrogen bonding interactions in protein folding and aggregation.

by Anthony W Fitzpatrick, Tuomas P J Knowles, Christopher A Waudby, Michele Vendruscolo, Christopher M Dobson
Published 2011-10-01

Structural reorganisation and potential toxicity of oligomeric species formed during the assembly of amyloid fibrils.

by Mookyung Cheon, Iksoo Chang, Sandipan Mohanty, Leila M Luheshi, Christopher M Dobson, Michele Vendruscolo, Giorgio Favrin
Published 2007-09-01