In silico, in vitro, and in vivo Approaches to Identify Molecular Players in Fragile X Tremor and Ataxia Syndrome

by Saif N. Haify, Teresa Botta-Orfila, Renate K. Hukema, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia
Published 2020-03-01

Aggregation is a Context-Dependent Constraint on Protein Evolution

by Michele Monti, Michele Monti, Alexandros Armaos, Alexandros Armaos, Marco Fantini, Annalisa Pastore, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia
Published 2021-06-01

A Method for RNA Structure Prediction Shows Evidence for Structure in lncRNAs

by Riccardo Delli Ponti, Riccardo Delli Ponti, Alexandros Armaos, Alexandros Armaos, Stefanie Marti, Stefanie Marti, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia, Gian Gaetano Tartaglia
Published 2018-12-01

Long non-coding RNA-polycomb intimate rendezvous

by Andrea Cerase, Gian Gaetano Tartaglia
Published 2020-09-01

Widespread Aggregation and Neurodegenerative Diseases Are Associated with Supersaturated Proteins

by Prajwal Ciryam, Gian Gaetano Tartaglia, Richard I. Morimoto, Christopher M. Dobson, Michele Vendruscolo
Published 2013-11-01

The mutational landscape of a prion-like domain

by Benedetta Bolognesi, Andre J. Faure, Mireia Seuma, Jörn M. Schmiedel, Gian Gaetano Tartaglia, Ben Lehner
Published 2019-09-01

A Concentration-Dependent Liquid Phase Separation Can Cause Toxicity upon Increased Protein Expression

by Benedetta Bolognesi, Nieves Lorenzo Gotor, Riddhiman Dhar, Davide Cirillo, Marta Baldrighi, Gian Gaetano Tartaglia, Ben Lehner
Published 2016-06-01

Computational optimization of angiotensin-converting enzyme 2 for SARS-CoV-2 Spike molecular recognition

by Lorenzo Di Rienzo, Michele Monti, Edoardo Milanetti, Mattia Miotto, Alberto Boffi, Gian Gaetano Tartaglia, Giancarlo Ruocco
Published 2021-01-01

Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments

by Michele Monti, Giulia Guiducci, Alessio Paone, Serena Rinaldo, Giorgio Giardina, Francesca Romana Liberati, Francesca Cutruzzolá, Gian Gaetano Tartaglia
Published 2021-01-01

RNA structure drives interaction with proteins

by Natalia Sanchez de Groot, Alexandros Armaos, Ricardo Graña-Montes, Marion Alriquet, Giulia Calloni, R. Martin Vabulas, Gian Gaetano Tartaglia
Published 2019-07-01

DnaK Functions as a Central Hub in the E. coli Chaperone Network

by Giulia Calloni, Taotao Chen, Sonya M. Schermann, Hung-chun Chang, Pierre Genevaux, Federico Agostini, Gian Gaetano Tartaglia, Manajit Hayer-Hartl, F. Ulrich Hartl
Published 2012-03-01

Systematic in vivo analysis of the intrinsic determinants of amyloid Beta pathogenicity.

by Leila M Luheshi, Gian Gaetano Tartaglia, Ann-Christin Brorsson, Amol P Pawar, Ian E Watson, Fabrizio Chiti, Michele Vendruscolo, David A Lomas, Christopher M Dobson, Damian C Crowther
Published 2007-10-01

Homage to Chris Dobson

by Jean Baum, Fabrizio Chiti, Alfonso De Simone, Tuomas P. J. Knowles, Janet R. Kumita, Sheena E. Radford, Carol V. Robinson, Xavier Salvatella, Karen Valelli, Michele Vendruscolo, Annalisa Pastore, Gian Gaetano Tartaglia
Published 2019-12-01

A metastable subproteome underlies inclusion formation in muscle proteinopathies

by Prajwal Ciryam, Matthew Antalek, Fernando Cid, Gian Gaetano Tartaglia, Christopher M. Dobson, Anne-Katrin Guettsches, Britta Eggers, Matthias Vorgerd, Katrin Marcus, Rudolf A. Kley, Richard I. Morimoto, Michele Vendruscolo, Conrad C. Weihl
Published 2019-12-01

An Integrative Study of Protein-RNA Condensates Identifies Scaffolding RNAs and Reveals Players in Fragile X-Associated Tremor/Ataxia Syndrome

by Fernando Cid-Samper, Mariona Gelabert-Baldrich, Benjamin Lang, Nieves Lorenzo-Gotor, Riccardo Delli Ponti, Lies-Anne W.F.M. Severijnen, Benedetta Bolognesi, Ellen Gelpi, Renate K. Hukema, Teresa Botta-Orfila, Gian Gaetano Tartaglia
Published 2018-12-01

Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate.

by Kiran Yanamandra, Oleg Alexeyev, Vladimir Zamotin, Vaibhav Srivastava, Andrei Shchukarev, Ann-Christin Brorsson, Gian Gaetano Tartaglia, Thomas Vogl, Rakez Kayed, Gunnar Wingsle, Jan Olsson, Christopher M Dobson, Anders Bergh, Fredrik Elgh, Ludmilla A Morozova-Roche
Published 2009-01-01