Advances and considerations in AD tau-targeted immunotherapy

by Alice Bittar, Nemil Bhatt, Rakez Kayed
Published 2020-02-01

Tau Protein: Function and Pathology

by Hanna Rosenmann, David Blum, Rakez Kayed, Lars M. Ittner
Published 2012-01-01

Curcumin as Scaffold for Drug Discovery against Neurodegenerative Diseases

by Filippa Lo Cascio, Paola Marzullo, Rakez Kayed, Antonio Palumbo Piccionello
Published 2021-02-01

Alzheimers Disease: Review of Emerging Treatment Role for Intravenous Immunoglobulins

by Rakez Kayed, George R. Jackson, D. Mark Estes, Alan D.T. Barrett
Published 2011-01-01

Alzheimers Disease: Review of Emerging Treatment Role for Intravenous Immunoglobulins

by Rakez Kayed, George R. Jackson, D. Mark Estes, Alan D.T. Barrett
Published 2011-05-01

P53 aggregation, interactions with tau, and impaired DNA damage response in Alzheimer’s disease

by Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt, Rakez Kayed
Published 2020-08-01

Formation of Toxic Oligomeric Assemblies of RNA-binding Protein: Musashi in Alzheimer’s disease

by Urmi Sengupta, Mauro Montalbano, Salome McAllen, Gerard Minuesa, Michael Kharas, Rakez Kayed
Published 2018-10-01

LDL phospholipid hydrolysis produces modified electronegative particles with an unfolded apoB-100 protein

by Liana Asatryan, Ryan T. Hamilton, J. Mario Isas, Juliana Hwang, Rakez Kayed, Alex Sevanian
Published 2005-01-01

ApoE4-Driven Accumulation of Intraneuronal Oligomerized Aβ42 following Activation of the Amyloid Cascade In Vivo Is Mediated by a Gain of Function

by Lia Zepa, Moran Frenkel, Haim Belinson, Zehavit Kariv-Inbal, Rakez Kayed, Eliezer Masliah, Daniel M. Michaelson
Published 2011-01-01

Amyloid Beta Annular Protofibrils in Cell Processes and Synapses Accumulate with Aging and Alzheimer-Associated Genetic Modification

by Hideko Kokubo, Rakez Kayed, Charles G. Glabe, Matthias Staufenbiel, Takaomi C. Saido, Nobuhisa Iwata, Haruyasu Yamaguchi
Published 2009-01-01

RNA-binding proteins Musashi and tau soluble aggregates initiate nuclear dysfunction

by Mauro Montalbano, Salome McAllen, Nicha Puangmalai, Urmi Sengupta, Nemil Bhatt, Omar D. Johnson, Michael G. Kharas, Rakez Kayed
Published 2020-08-01

Early alterations of neurovascular unit in the retina in mouse models of tauopathy

by Fan Xia, Yonju Ha, Shuizhen Shi, Yi Li, Shengguo Li, Jonathan Luisi, Rakez Kayed, Massoud Motamedi, Hua Liu, Wenbo Zhang
Published 2021-03-01

Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy

by Julia E. Gerson, Kathleen M. Farmer, Natalie Henson, Diana L. Castillo-Carranza, Mariana Carretero Murillo, Urmi Sengupta, Alan Barrett, Rakez Kayed
Published 2018-03-01

TDP-43 and Tau Oligomers in Alzheimer's Disease, Amyotrophic Lateral Sclerosis, and Frontotemporal Dementia

by Mauro Montalbano, Salome McAllen, Filippa Lo Cascio, Urmi Sengupta, Stephanie Garcia, Nemil Bhatt, Anna Ellsworth, Eric A. Heidelman, Omar D. Johnson, Samantha Doskocil, Rakez Kayed
Published 2020-12-01

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

by Marcos J. Guerrero-Muñoz, Diana L. Castillo-Carranza, Shashirekha Krishnamurthy, Adriana A. Paulucci-Holthauzen, Urmi Sengupta, Cristian A. Lasagna-Reeves, Yembur Ahmad, George R. Jackson, Rakez Kayed
Published 2014-11-01

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes

by Cristian A Lasagna-Reeves, Maxime WC Rousseaux, Marcos J Guerrero-Munoz, Luis Vilanova-Velez, Jeehye Park, Lauren See, Paymaan Jafar-Nejad, Ronald Richman, Harry T Orr, Rakez Kayed, Huda Y Zoghbi
Published 2015-12-01

Prefibrillar Tau oligomers alter the nucleic acid protective function of Tau in hippocampal neurons in vivo

by Marie Violet, Alban Chauderlier, Lucie Delattre, Meryem Tardivel, Meliza Sendid Chouala, Audrey Sultan, Elodie Marciniak, Sandrine Humez, Lester Binder, Rakez Kayed, Bruno Lefebvre, Eliette Bonnefoy, Luc Buée, Marie-Christine Galas
Published 2015-10-01

A native interactor scaffolds and stabilizes toxic ATAXIN-1 oligomers in SCA1

by Cristian A Lasagna-Reeves, Maxime WC Rousseaux, Marcos J Guerrero-Muñoz, Jeehye Park, Paymaan Jafar-Nejad, Ronald Richman, Nan Lu, Urmi Sengupta, Alexandra Litvinchuk, Harry T Orr, Rakez Kayed, Huda Y Zoghbi
Published 2015-05-01

Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate.

by Kiran Yanamandra, Oleg Alexeyev, Vladimir Zamotin, Vaibhav Srivastava, Andrei Shchukarev, Ann-Christin Brorsson, Gian Gaetano Tartaglia, Thomas Vogl, Rakez Kayed, Gunnar Wingsle, Jan Olsson, Christopher M Dobson, Anders Bergh, Fredrik Elgh, Ludmilla A Morozova-Roche
Published 2009-01-01

Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model

by YoungDoo Kim, Hyunwoo Choi, WonJae Lee, Hyejin Park, Tae-In Kam, Se-hoon Hong, Jihoon Nah, Sunmin Jung, Bora Shin, Huikyong Lee, Tae-Yong Choi, Hyosun Choo, Kyung-Keun Kim, Se-Young Choi, Rakez Kayed, Yong-Keun Jung
Published 2016-03-01