A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair

by Zachary K. Boswell, Samiur Rahman, Marella D. Canny, Michael P. Latham
Published 2018-01-01

A Survey of Reported Disease-Related Mutations in the MRE11-RAD50-NBS1 Complex

by Samiur Rahman, Marella D. Canny, Tanner A. Buschmann, Michael P. Latham
Published 2020-07-01

Nucleosome acidic patch promotes RNF168- and RING1B/BMI1-dependent H2AX and H2A ubiquitination and DNA damage signaling.

by Justin W Leung, Poonam Agarwal, Marella D Canny, Fade Gong, Aaron D Robison, Ilya J Finkelstein, Daniel Durocher, Kyle M Miller
Published 2014-03-01

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

by Julianne Kitevski-LeBlanc, Amélie Fradet-Turcotte, Predrag Kukic, Marcus D Wilson, Guillem Portella, Tairan Yuwen, Stephanie Panier, Shili Duan, Marella D Canny, Hugo van Ingen, Cheryl H Arrowsmith, John L Rubinstein, Michele Vendruscolo, Daniel Durocher, Lewis E Kay
Published 2017-04-01