LiPS-A3S, a human genomic site for robust expression of inserted transgenes

by Andriana G Kotini, Michel Sadelain, Eirini P Papapetrou
Published 2016-01-01

CD19 CAR-targeted T cells induce long-term remission and B Cell Aplasia in an immunocompetent mouse model of B cell acute lymphoblastic leukemia.

by Marco L Davila, Christopher C Kloss, Gertrude Gunset, Michel Sadelain
Published 2013-01-01

Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition.

by Maud Condomines, Jon Arnason, Reuben Benjamin, Gertrude Gunset, Jason Plotkin, Michel Sadelain
Published 2015-01-01

137 Genomics of multiple myeloma influences the expression of CAR T-cell targets

by Michel Sadelain, Christina Yu, Brian Walker, G David Roodman, Kun Huang, Fabiana Perna
Published 2020-11-01

Escape Mutations, Ganciclovir Resistance, and Teratoma Formation in Human iPSCs Expressing an HSVtk Suicide Gene

by Andriana G Kotini, Elisa de Stanchina, Maria Themeli, Michel Sadelain, Eirini P Papapetrou
Published 2016-01-01

Cancer Patient T Cells Genetically Targeted to Prostate-Specific Membrane Antigen Specifically Lyse Prostate Cancer Cells and Release Cytokines in Response to Prostate-Specific Mem...

by Michael C. Gong, Jean-Baptiste Latouche, Anja Krause, Warren D.W. Heston, Neil H. Bander, Michel Sadelain
Published 1999-06-01

An in vivo platform for tumor biomarker assessment.

by Elliot L Servais, Kei Suzuki, Christos Colovos, Luis Rodriguez, Camelia Sima, Martin Fleisher, Valerie W Rusch, Michel Sadelain, Prasad S Adusumilli
Published 2011-01-01

An MHC-restricted antibody-based chimeric antigen receptor requires TCR-like affinity to maintain antigen specificity

by Marcela V Maus, Jason Plotkin, Gopinadh Jakka, Guillaume Stewart-Jones, Isabelle Rivière, Taha Merghoub, Jedd Wolchok, Christoph Renner, Michel Sadelain
Published 2016-01-01

Combination of the PI3K Inhibitor ZSTK474 with a PSMA-Targeted Immunotoxin Accelerates Apoptosis and Regression of Prostate Cancer

by Daniele Baiz, Sazzad Hassan, Young A Choi, Anabel Flores, Yelena Karpova, Dana Yancey, Ashok Pullikuth, Guangchao Sui, Michel Sadelain, Waldemar Debinski, George Kulik
Published 2013-10-01

Recovery and Biodistribution of Ex Vivo Expanded Human Erythroblasts Injected into NOD/SCID/IL2Rγnull mice

by Barbara Ghinassi, Leda Ferro, Francesca Masiello, Valentina Tirelli, Massimo Sanchez, Giovanni Migliaccio, Carolyn Whitsett, Stefan Kachala, Isabelle Riviere, Michel Sadelain, Anna Rita Migliaccio
Published 2011-01-01

A General Approach to the Non-Invasive Imaging of Transgenes Using Cis-Linked Herpes Simplex Virus Thymidine Kinase

by Juri G. Tjuvajev, Arjun Joshi, James Callegari, Laura Lindsley, Revathi Joshi, Julius Balaton, Ronald Find, Steven M. Larso, Michel Sadelain, Ronald G. Blasberg
Published 1999-10-01

Imaging TCR-Dependent NFAT-Mediated T-Cell Activation with Positron Emission Tomography In Vivo

by Vladimir Ponomarev, Michael Doubrovin, Clay Lyddane, Tatiana Beresten, Julius Balatoni, William Bornman, Ronald Finn, Timothy Akhurst, Steven Larson, Ronald Blasberg, Michel Sadelain, Juri Gelovani Tjuvajev
Published 2001-01-01

Development of a New Reporter Gene System-dsRed/Xanthine Phosphoribosyltransferase-Xanthine for Molecular Imaging of Processes Behind the Intact Blood-Brain Barrier

by Mikhail Doubrovin, Vladimir Ponomarev, Inna Serganova, Suren Soghomonian, Tadashi Myagawa, Tatiana Beresten, Lyudmila Ageyeva, Michel Sadelain, Jason Koutcher, Ronald G Blasberg, Juri G. Gelovani Tjuvajev
Published 2003-04-01

A Cell Engineering Strategy to Enhance the Safety of Stem Cell Therapies

by Elisa Oricchio, Eirini P. Papapetrou, Fabien Lafaille, Yosif M. Ganat, Sonja Kriks, Ana Ortega-Molina, Willie H. Mark, Julie Teruya-Feldstein, Jason T. Huse, Victor Reuter, Michel Sadelain, Lorenz Studer, Hans-Guido Wendel
Published 2014-09-01

The Polycomb Group Protein L3MBTL1 Represses a SMAD5-Mediated Hematopoietic Transcriptional Program in Human Pluripotent Stem Cells

by Fabiana Perna, Ly P. Vu, Maria Themeli, Sonja Kriks, Ruben Hoya-Arias, Raya Khanin, Todd Hricik, Jorge Mansilla-Soto, Eirini P. Papapetrou, Ross L. Levine, Lorenz Studer, Michel Sadelain, Stephen D. Nimer
Published 2015-04-01

Adenoviral transduction of human acid sphingomyelinase into neo-angiogenic endothelium radiosensitizes tumor cure.

by Branka Stancevic, Nira Varda-Bloom, Jin Cheng, John D Fuller, Jimmy A Rotolo, Mónica García-Barros, Regina Feldman, Shyam Rao, Ralph R Weichselbaum, Dror Harats, Adriana Haimovitz-Friedman, Zvi Fuks, Michel Sadelain, Richard Kolesnick
Published 2013-01-01

Screening Clinical Cell Products for Replication Competent Retrovirus: The National Gene Vector Biorepository Experience

by Kenneth Cornetta, Lisa Duffy, Steven A. Feldman, Crystal L. Mackall, Marco L. Davila, Kevin J. Curran, Richard P. Junghans, Jean Yuh Tang, James N. Kochenderfer, Roisin O’Cearbhaill, Gary Archer, Hans-Peter Kiem, Nirali N. Shah, Cindy Delbrook, Rosie Kaplan, Renier J. Brentjens, Isabelle Rivière, Michel Sadelain, Steven A. Rosenberg
Published 2018-09-01

Proceedings of the 2016 China Cancer Immunotherapy Workshop

by Bin Xue, Jiaqi Xu, Wenru Song, Zhimin Yang, Ke Liu, Zihai Li, Zihai Li, Lieping Chen, Edward B. Garon, Siwen Hu-Lieskovan, Wei Ding, Chong-Xian Pan, Weijing Sun, Yong-Jun Liu, Lei Zheng, Delong Liu, Michel Sadelain, Cassian Yee, Rongfu Wang, Meixia Chen, Yao Wang, Zhiqiang Wu, Hanren Dai, Can Luo, Yang Liu, Chuan Tong, Yelei Guo, Qingming Yang, Weidong Han, Lisa H. Butterfield, Timothy A. Chan, Wenru Song, Ruirong Yuan, Bo Lu, Ke Liu, Max Ning, Harald Enzmann, Heinz Zwierzina
Published 2016-10-01