Zihai Li

Zihai Li is a board-certified medical oncologist, cancer immunologist, and leader in academic medicine. He was recruited to Ohio State University Comprehensive Cancer Center – The James Cancer Hospital & Solove Research Institute (OSUCCC) in 2019 as the founding director of the Pelotonia Institute for Immuno-Oncology. He is a professor of medicine in the Division of Medical Oncology, holds the Klotz Memorial Chair for Cancer Research, and was appointed in 2023 as deputy director for translational research at OSUCCC.

Li's research interests primarily focus on the fields of chaperone biology, immune tolerance, cancer immunology and immunotherapy. He has been continuously funded by the National Institutes of Health (NIH) since 2000, with total funding of over $30 million. Provided by Wikipedia
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  1. 1
    The Emerging Roles of Endoplasmic Reticulum Stress in Balancing Immunity and Tolerance in Health and Diseases: Mechanisms and Opportunities
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  2. 2
    In vivo and in situ programming of tumor immunity by combining oncolytics and PD-1 immune checkpoint blockade
    by Eric Bartee, Zihai Li
    Published 2017-05-01
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  3. 3
    Murine but not human basophil undergoes cell-specific proteolysis of a major endoplasmic reticulum chaperone.
    by Bei Liu, Matthew Staron, Zihai Li
    Published 2012-01-01
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  4. 4
    Recent updates in cancer immunotherapy: a comprehensive review and perspective of the 2018 China Cancer Immunotherapy Workshop in Beijing
    by Zihai Li, Wenru Song, Mark Rubinstein, Delong Liu
    Published 2018-12-01
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  5. 5
    Is CD47 an innate immune checkpoint for tumor evasion?
    by Xiaojuan Liu, Hyunwoo Kwon, Zihai Li, Yang-xin Fu
    Published 2017-01-01
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  6. 6
    Development of molecular and pharmacological switches for chimeric antigen receptor T cells
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  7. 7
    Sex differences in monocyte activation in systemic lupus erythematosus (SLE).
    by Wei Jiang, Lumin Zhang, Ren Lang, Zihai Li, Gary Gilkeson
    Published 2014-01-01
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  8. 8
    COVID-19 vaccines for patients with cancer: benefits likely outweigh risks
    by Joyce K. Hwang, Tian Zhang, Andrew Z. Wang, Zihai Li
    Published 2021-02-01
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  9. 9
    Oocyte-targeted deletion reveals that hsp90b1 is needed for the completion of first mitosis in mouse zygotes.
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  10. 10
    Novel strategies for immuno-oncology breakthroughs with cell therapy
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  11. 11
    Correction: Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker
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  12. 12
    Structural and Functional Analysis of GRP94 in the Closed State Reveals an Essential Role for the Pre-N Domain and a Potential Client-Binding Site
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  13. 13
    Correction: Molecular Profiling of Multiple Human Cancers Defines an Inflammatory Cancer-Associated Molecular Pattern and Uncovers KPNA2 as a Uniform Poor Prognostic Cancer Marker.
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    Article
  14. 14
    Molecular profiling of multiple human cancers defines an inflammatory cancer-associated molecular pattern and uncovers KPNA2 as a uniform poor prognostic cancer marker.
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  15. 15
    PD-1, PD-L1 (B7-H1) and Tumor-Site Immune Modulation Therapy: The Historical Perspective
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  16. 16
    Regulation of dendritic cell function improves survival in experimental sepsis through immune chaperone
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  17. 17
    Next-generation immuno-oncology agents: current momentum shifts in cancer immunotherapy
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  18. 18
    Myeloid Endoplasmic Reticulum Resident Chaperone GP96 Facilitates Inflammation and Steatosis in Alcohol‐Associated Liver Disease
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  19. 19
    Gut homeostasis and regulatory T cell induction depend on molecular chaperone gp96 in CD11c+ cells
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  20. 20
    Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer
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