Is CD47 an innate immune checkpoint for tumor evasion?

by Xiaojuan Liu, Hyunwoo Kwon, Zihai Li, Yang-xin Fu
Published 2017-01-01

Differential regulation of breast cancer bone metastasis by PARP1 and PARP2

by Hao Zuo, Dengbao Yang, Qiwen Yang, Haidong Tang, Yang-Xin Fu, Yihong Wan
Published 2020-03-01

LIGHT induces distinct signals to clear an AAV-expressed persistent antigen in the mouse liver and to induce liver inflammation.

by Michael L Washburn, Grigoriy I Kovalev, Ekaterina Koroleva, Yang-Xin Fu, Lishan Su
Published 2010-05-01

Methylseleninic acid sensitizes Notch3-activated OVCA429 ovarian cancer cells to carboplatin.

by Tiffany J Tzeng, Lei Cao, YangXin Fu, Huawei Zeng, Wen-Hsing Cheng
Published 2014-01-01

Pharmacological Inhibition of p38 MAPK by SB203580 Increases Resistance to Carboplatin in A2780cp Cells and Promotes Growth in Primary Ovarian Cancer Cells

by Xiaolu Han, Huachen Chen, Jiesi Zhou, Helen Steed, Lynne-Marie Postovit, YangXin Fu
Published 2018-07-01

Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth

by Huilin Zheng, Weibin Zou, Jiaying Shen, Liang Xu, Shu Wang, Yang-Xin Fu, Weimin Fan
Published 2016-09-01

A cytokine receptor-masked IL2 prodrug selectively activates tumor-infiltrating lymphocytes for potent antitumor therapy

by Eric J. Hsu, Xuezhi Cao, Benjamin Moon, Joonbeom Bae, Zhichen Sun, Zhida Liu, Yang-Xin Fu
Published 2021-05-01

LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells.

by Bijoy Chellan, Ekaterina P Koroleva, Timothy J Sontag, Alexei V Tumanov, Yang-Xin Fu, Godfrey S Getz, Catherine A Reardon
Published 2013-01-01

Next generation of tumor-activating type I IFN enhances anti-tumor immune responses to overcome therapy resistance

by Xuezhi Cao, Yong Liang, Zhenxiang Hu, Huiyu Li, Jiaming Yang, Eric J. Hsu, Jiankun Zhu, Jin Zhou, Yang-Xin Fu
Published 2021-10-01

PD-L1 on dendritic cells attenuates T cell activation and regulates response to immune checkpoint blockade

by Qi Peng, Xiangyan Qiu, Zihan Zhang, Silin Zhang, Yuanyuan Zhang, Yong Liang, Jingya Guo, Hua Peng, Mingyi Chen, Yang-Xin Fu, Haidong Tang
Published 2020-09-01

NQO1 targeting prodrug triggers innate sensing to overcome checkpoint blockade resistance

by Xiaoguang Li, Zhida Liu, Anli Zhang, Chuanhui Han, Aijun Shen, Lingxiang Jiang, David A. Boothman, Jian Qiao, Yang Wang, Xiumei Huang, Yang-Xin Fu
Published 2019-07-01

A bioactive mammalian disaccharide associated with autoimmunity activates STING-TBK1-dependent immune response

by Charles S. Fermaintt, Kanae Sano, Zhida Liu, Nozomi Ishii, Junichi Seino, Nicole Dobbs, Tadashi Suzuki, Yang-Xin Fu, Mark A. Lehrman, Ichiro Matsuo, Nan Yan
Published 2019-05-01

Tolerogenic properties of lymphatic endothelial cells are controlled by the lymph node microenvironment.

by Jarish N Cohen, Eric F Tewalt, Sherin J Rouhani, Erica L Buonomo, Amber N Bruce, Xiaojiang Xu, Stefan Bekiranov, Yang-Xin Fu, Victor H Engelhard
Published 2014-01-01

Host STING-dependent MDSC mobilization drives extrinsic radiation resistance

by Hua Liang, Liufu Deng, Yuzhu Hou, Xiangjiao Meng, Xiaona Huang, Enyu Rao, Wenxin Zheng, Helena Mauceri, Matthias Mack, Meng Xu, Yang-Xin Fu, Ralph R. Weichselbaum
Published 2017-11-01

RUNX3 Promotes the Tumorigenic Phenotype in KGN, a Human Granulosa Cell Tumor-Derived Cell Line

by Huachen Chen, Powel Crosley, Abul K. Azad, Nidhi Gupta, Nisha Gokul, Zhihua Xu, Michael Weinfeld, Lynne-Marie Postovit, Stephanie A. Pangas, Mary M. Hitt, YangXin Fu
Published 2019-07-01

LTβR controls thymic portal endothelial cells for haematopoietic progenitor cell homing and T-cell regeneration

by Yaoyao Shi, Weiwei Wu, Qian Chai, Qingqing Li, Yu Hou, Huan Xia, Boyang Ren, Hairong Xu, Xiaohuan Guo, Caiwei Jin, Mengjie Lv, Zhongnan Wang, Yang-Xin Fu, Mingzhao Zhu
Published 2016-08-01

CD160 Plays a Protective Role During Chronic Infection by Enhancing Both Functionalities and Proliferative Capacity of CD8+ T Cells

by Linxia Zhang, Anli Zhang, Anli Zhang, Jun Xu, Chao Qiu, Lingyan Zhu, Chenli Qiu, Weihui Fu, Ying Wang, Lilin Ye, Yang-xin Fu, Chen Zhao, Xiaoyan Zhang, Jianqing Xu
Published 2020-09-01

Author Correction: A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control

by Zhichen Sun, Zhenhua Ren, Kaiting Yang, Zhida Liu, Shuaishuai Cao, Sisi Deng, Lily Xu, Yong Liang, Jingya Guo, Yingjie Bian, Hairong Xu, Jiyun Shi, Fan Wang, Yang-Xin Fu, Hua Peng
Published 2020-04-01

A next-generation tumor-targeting IL-2 preferentially promotes tumor-infiltrating CD8+ T-cell response and effective tumor control

by Zhichen Sun, Zhenhua Ren, Kaiting Yang, Zhida Liu, Shuaishuai Cao, Sisi Deng, Lily Xu, Yong Liang, Jingya Guo, Yingjie Bian, Hairong Xu, Jiyun Shi, Fan Wang, Yang-Xin Fu, Hua Peng
Published 2019-08-01

Targeting IFNα to tumor by anti-PD-L1 creates feedforward antitumor responses to overcome checkpoint blockade resistance

by Yong Liang, Haidong Tang, Jingya Guo, Xiangyan Qiu, Zecheng Yang, Zhenhua Ren, Zhichen Sun, Yingjie Bian, Lily Xu, Hairong Xu, Jiao Shen, Yanfei Han, Haidong Dong, Hua Peng, Yang-Xin Fu
Published 2018-11-01