Characterisation of the Candida albicans Phosphopantetheinyl Transferase Ppt2 as a Potential Antifungal Drug Target.

by Katharine S Dobb, Sarah J Kaye, Nicola Beckmann, John L Thain, Lubomira Stateva, Mike Birch, Jason D Oliver
Published 2015-01-01

In Vitro Activity of Novel Antifungal Olorofim against Filamentous Fungi and Comparison to Eight Other Antifungal Agents

by Ourania Georgacopoulos, Natalie S. Nunnally, Eric M. Ransom, Derek Law, Mike Birch, Shawn R. Lockhart, Elizabeth L. Berkow
Published 2021-05-01

The Dynamic Influence of Olorofim (F901318) on the Cell Morphology and Organization of Living Cells of <i>Aspergillus fumigatus</i>

by Saskia du Pré, Mike Birch, Derek Law, Nicola Beckmann, Graham E.M. Sibley, Michael J. Bromley, Nick D. Read, Jason D. Oliver
Published 2020-04-01

The Aspergillus fumigatus dihydroxyacid dehydratase Ilv3A/IlvC is required for full virulence.

by Jason D Oliver, Sarah J Kaye, Danny Tuckwell, Anna E Johns, Darel A Macdonald, Joanne Livermore, Peter A Warn, Mike Birch, Michael J Bromley
Published 2012-01-01

A Nonredundant Phosphopantetheinyl Transferase, PptA, Is a Novel Antifungal Target That Directs Secondary Metabolite, Siderophore, and Lysine Biosynthesis in Aspergillus fumigatus...

by Anna Johns, Daniel H. Scharf, Fabio Gsaller, Hella Schmidt, Thorsten Heinekamp, Maria Straßburger, Jason D. Oliver, Mike Birch, Nicola Beckmann, Katharine S. Dobb, Jane Gilsenan, Bharatkumar Rash, Elaine Bignell, Axel A. Brakhage, Michael J. Bromley, Jeffrey P. Henderson, Scott J. Hultgren
Published 2017-07-01