A Multi-Omics Interpretable Machine Learning Model Reveals Modes of Action of Small Molecules

by Patel-Murray, Natasha Leanna, Adam, Miriam, Huynh, Nhan C, Wassie, Brook T., Milani, Pamela, Fraenkel, Ernest
Published 2020

Revealing disease-associated pathways by network integration of untargeted metabolomics

by Leidl, Mathias, Avila-Pacheco, Julian, Pirhaji, Leila, Milani, Pamela, Curran, Timothy G., Clish, Clary, Saghatelian, Alan, Fraenkel, Ernest, White, Forest M.
Published 2018

Network Modeling Identifies Patient-specific Pathways in Glioblastoma

by Pokorny, Jenny L., Sio, Terence T., Iyekegbe, Dennis O., Sarkaria, Jann N., Tuncbag, Nurcan, Milani, Pamela, Johnson, Hannah, Dalin, Simona, Fraenkel, Ernest, White, Forest M.
Published 2017

Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells

by Shelley, Brandon C., Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N., Milani, Pamela, Escalante, Renan A., Patel-Murray, Natasha Leanna, Xin, Xiaofeng, Adam, Miriam, Fraenkel, Ernest
Published 2017

Cell freezing protocol suitable for ATAC-Seq on motor neurons derived from human induced pluripotent stem cells

by Shelley, Brandon C., Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N., Milani, Pamela, Escalante, Renan A., Patel-Murray, Natasha Leanna, Xin, Xiaofeng, Adam, Miriam, Fraenkel, Ernest
Published 2017

Identifying therapeutic targets by combining transcriptional data with ordinal clinical measurements

by Dunn, Denise E., Avila-Pacheco, Julian, Greengard, Paul, Clish, Clary B., Lo, Donald C., Pirhaji, Leila, Milani, Pamela, Dalin, Simona, Wassie, Brook T., Fenster, Robert, Heiman, Myriam, Fraenkel, Ernest
Published 2017

Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM

by Wong, Siu Lun, Cui, Cheryl, Pregernig, Gabriela, Milani, Pamela, Choi, Gigi C. G., Adam, Miriam, Perli, Samuel D., Kazer, Samuel Weisgurt, Gaillard de Saint Germain, Alethe, Hermann, Mario, Shalek, Alexander K, Fraenkel, Ernest, Lu, Timothy K
Published 2017

Elucidating MicroRNA Regulatory Networks Using Transcriptional, Post-transcriptional, and Histone Modification Measurements

by Gurtan, Allan M, JnBaptiste, Courtney K, Bosson, Andrew, Milani, Pamela, Matthews, Bryan J, Yap, Yoon S, Sharp, Phillip A., Fraenkel, Ernest, Gosline, Sara Jane Calafell, Gurtan, Allan M., Sharp, Phillip A., Dalin, Simona, JnBaptiste, Courtney Kenneil, Matthews, Bryan, Yap, Yoon Sing
Published 2016

Developmental alterations in Huntington's disease neural cells and pharmacological rescue in cells and mice

by HD iPSC Consortium, Lim, Ryan G, Salazar, Lisa L, Wilton, Daniel K, King, Alvin R, Stocksdale, Jennifer T, Sharifabad, Delaram, Lau, L Alice, Stevens, Beth, Reidling, Jack C, Winokur, Sara T, Casale, Malcolm S, Thompson, Leslie M, Pardo, Mónica, Díaz-Barriga, A Gerardo García, Straccia, Marco, Sanders, Phil, Alberch, Jordi, Canals, Josep M, Kaye, Julia A, Dunlap, Mariah, Jo, Lisa, May, Hanna, Mount, Elliot, Anderson-Bergman, Cliff, Haston, Kelly, Finkbeiner, Steven, Allen, Nicholas D, Kemp, Paul J, Atwal, Ranjit Singh, Biagioli, Marta, Gusella, James F, MacDonald, Marcy E, Akimov, Sergey S, Arbez, Nicolas, Stewart, Jacqueline, Ross, Christopher A, Mattis, Virginia B, Tom, Colton M, Mattis, Virginia B, Tom, Colton M, Ornelas, Loren, Sahabian, Anais, Lenaeus, Lindsay, Mandefro, Berhan, Sareen, Dhruv, Svendsen, Clive N, Kedaigle, Amanda Joy, Wasylenko, Theresa Anne, Yildirim, Ferah, Ng, Christopher W., Milani, Pamela, Housman, David E, Fraenkel, Ernest
Published 2018