Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy

by Sang-Min Jang, Christophe E. Redon, Mirit I. Aladjem
Published 2018-03-01

Predicted functions of MdmX in fine-tuning the response of p53 to DNA damage.

by Sohyoung Kim, Mirit I Aladjem, Geoffrey B McFadden, Kurt W Kohn
Published 2010-02-01

Predicted Role of NAD Utilization in the Control of Circadian Rhythms during DNA Damage Response.

by Augustin Luna, Geoffrey B McFadden, Mirit I Aladjem, Kurt W Kohn
Published 2015-05-01

Interactions of MCP1 with Components of the Replication Machinery in Mammalian Cells

by Elsa Bronze-da-Rocha, Chii-Mei Lin, Tsutomu Shimura, Mirit I. Aladjem
Published 2011-01-01

Regulation of cell cycle drivers by Cullin-RING ubiquitin ligases

by Sang-Min Jang, Christophe E. Redon, Bhushan L. Thakur, Meriam K. Bahta, Mirit I. Aladjem
Published 2020-10-01

DNA methylation supports intrinsic epigenetic memory in mammalian cells.

by Yong-Qing Feng, Romain Desprat, Haiqing Fu, Emmanuel Olivier, Chii Mei Lin, Amanda Lobell, Shilpa N Gowda, Mirit I Aladjem, Eric E Bouhassira
Published 2006-04-01

Correction: Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle

by Haiqing Fu, Alika K. Maunakea, Melvenia M. Martin, Liang Huang, Ya Zhang, Michael Ryan, RyangGuk Kim, Chii Meil Lin, Keji Zhao, Mirit I. Aladjem
Published 2013-07-01

HPV integration hijacks and multimerizes a cellular enhancer to generate a viral-cellular super-enhancer that drives high viral oncogene expression.

by Alix Warburton, Catherine J Redmond, Katharine E Dooley, Haiqing Fu, Maura L Gillison, Keiko Akagi, David E Symer, Mirit I Aladjem, Alison A McBride
Published 2018-01-01

Methylation of histone H3 on lysine 79 associates with a group of replication origins and helps limit DNA replication once per cell cycle.

by Haiqing Fu, Alika K Maunakea, Melvenia M Martin, Liang Huang, Ya Zhang, Michael Ryan, RyangGuk Kim, Chii Meil Lin, Keji Zhao, Mirit I Aladjem
Published 2013-06-01

Correction: Methylation of Histone H3 on Lysine 79 Associates with a Group of Replication Origins and Helps Limit DNA Replication Once per Cell Cycle.

by Haiqing Fu, Alika K. Maunakea, Melvenia M. Martin, Liang Huang, Ya Zhang, Michael Ryan, RyangGuk Kim, Chii Meil Lin, Keji Zhao, Mirit I. Aladjem
Published 2013-07-01

Preferential localization of human origins of DNA replication at the 5'-ends of expressed genes and at evolutionarily conserved DNA sequences.

by Manuel S Valenzuela, Yidong Chen, Sean Davis, Fan Yang, Robert L Walker, Sven Bilke, John Lueders, Melvenia M Martin, Mirit I Aladjem, Pierre P Massion, Paul S Meltzer
Published 2011-01-01

The epigenetic regulator LSH maintains fork protection and genomic stability via MacroH2A deposition and RAD51 filament formation

by Xiaoping Xu, Kai Ni, Yafeng He, Jianke Ren, Chongkui Sun, Yie Liu, Mirit I. Aladjem, Sandra Burkett, Richard Finney, Xia Ding, Shyam K. Sharan, Kathrin Muegge
Published 2021-06-01

Allele-specific genome-wide profiling in human primary erythroblasts reveal replication program organization.

by Rituparna Mukhopadhyay, Julien Lajugie, Nicolas Fourel, Ari Selzer, Michael Schizas, Boris Bartholdy, Jessica Mar, Chii Mei Lin, Melvenia M Martin, Michael Ryan, Mirit I Aladjem, Eric E Bouhassira
Published 2014-05-01

The replication initiation determinant protein (RepID) modulates replication by recruiting CUL4 to chromatin

by Sang-Min Jang, Ya Zhang, Koichi Utani, Haiqing Fu, Christophe E. Redon, Anna B. Marks, Owen K. Smith, Catherine J. Redmond, Adrian M. Baris, Danielle A. Tulchinsky, Mirit I. Aladjem
Published 2018-07-01

ORCA/LRWD1 Regulates Homologous Recombination at ALT-Telomeres by Modulating Heterochromatin Organization

by Rosaline Y.C. Hsu, Yo-Chuen Lin, Christophe Redon, Qinyu Sun, Deepak K. Singh, Yating Wang, Vasudha Aggarwal, Jaba Mitra, Abhijith Matur, Branden Moriarity, Taekjip Ha, Mirit I. Aladjem, Kannanganattu V. Prasanth, Supriya G. Prasanth
Published 2020-05-01

BAMscale: quantification of next-generation sequencing peaks and generation of scaled coverage tracks

by Lorinc S. Pongor, Jacob M. Gross, Roberto Vera Alvarez, Junko Murai, Sang-Min Jang, Hongliang Zhang, Christophe Redon, Haiqing Fu, Shar-Yin Huang, Bhushan Thakur, Adrian Baris, Leonardo Marino-Ramirez, David Landsman, Mirit I. Aladjem, Yves Pommier
Published 2020-04-01

The RepID–CRL4 ubiquitin ligase complex regulates metaphase to anaphase transition via BUB3 degradation

by Sang-Min Jang, Jenny F. Nathans, Haiqing Fu, Christophe E. Redon, Lisa M. Jenkins, Bhushan L. Thakur, Lőrinc S. Pongor, Adrian M. Baris, Jacob M. Gross, Maura J. OʹNeill, Fred E. Indig, Steven D. Cappell, Mirit I. Aladjem
Published 2020-01-01

A replicator-specific binding protein essential for site-specific initiation of DNA replication in mammalian cells

by Ya Zhang, Liang Huang, Haiqing Fu, Owen K. Smith, Chii Mei Lin, Koichi Utani, Mishal Rao, William C. Reinhold, Christophe E. Redon, Michael Ryan, RyangGuk Kim, Yang You, Harlington Hanna, Yves Boisclair, Qiaoming Long, Mirit I. Aladjem
Published 2016-06-01

CellMinerCDB for Integrative Cross-Database Genomics and Pharmacogenomics Analyses of Cancer Cell Lines

by Vinodh N. Rajapakse, Augustin Luna, Mihoko Yamade, Lisa Loman, Sudhir Varma, Margot Sunshine, Francesco Iorio, Fabricio G. Sousa, Fathi Elloumi, Mirit I. Aladjem, Anish Thomas, Chris Sander, Kurt W. Kohn, Cyril H. Benes, Mathew Garnett, William C. Reinhold, Yves Pommier
Published 2018-12-01

Dynamics of replication origin over-activation

by Haiqing Fu, Christophe E. Redon, Bhushan L. Thakur, Koichi Utani, Robin Sebastian, Sang-Min Jang, Jacob M. Gross, Sara Mosavarpour, Anna B. Marks, Sophie Z. Zhuang, Sarah B. Lazar, Mishal Rao, Shira T. Mencer, Adrian M. Baris, Lorinc S. Pongor, Mirit I. Aladjem
Published 2021-06-01