HIV efficiently infects T cells from the endometrium and remodels them to promote systemic viral spread

by Tongcui Ma, Xiaoyu Luo, Ashley F George, Gourab Mukherjee, Nandini Sen, Trimble L Spitzer, Linda C Giudice, Warner C Greene, Nadia R Roan
Published 2020-05-01

No detectable alloreactive transcriptional responses under standard sample preparation conditions during donor-multiplexed single-cell RNA sequencing of peripheral blood mononuclea...

by Christopher S. McGinnis, David A. Siegel, Guorui Xie, George Hartoularos, Mars Stone, Chun J. Ye, Zev J. Gartner, Nadia R. Roan, Sulggi A. Lee
Published 2021-01-01

Effects of the levonorgestrel-containing intrauterine device, copper intrauterine device, and levonorgestrel-containing oral contraceptive on susceptibility of immune cells from ce...

by Marielle Cavrois, Joan F Hilton, Nadia R Roan, Margaret Takeda, Dominika Seidman, Sarah Averbach, Eric Chang, Nandhini Raman, Ruth Greenblatt, Barbara L Shacklett, Karen Smith-McCune
Published 2019-01-01

SARS-CoV-2-Specific T Cells Exhibit Phenotypic Features of Helper Function, Lack of Terminal Differentiation, and High Proliferation Potential

by Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Gurjot Gill, Ellen S. Stein, Matthew McGregor, Tongcui Ma, Ashley F. George, Astrid Kosters, Warner C. Greene, Joshua Vasquez, Eliver Ghosn, Sulggi Lee, Nadia R. Roan
Published 2020-09-01

Sialyl-LewisX Glycoantigen Is Enriched on Cells with Persistent HIV Transcription during Therapy

by Florent Colomb, Leila B. Giron, Leticia Kuri-Cervantes, Opeyemi S. Adeniji, Tongcui Ma, Harsh Dweep, Emilie Battivelli, Eric Verdin, Clovis S. Palmer, Hiroaki Tateno, Andrew V. Kossenkov, Nadia R. Roan, Michael R. Betts, Mohamed Abdel-Mohsen
Published 2020-08-01

Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection.

by Feng Hsiao, Julie Frouard, Andrea Gramatica, Guorui Xie, Sushama Telwatte, Guinevere Q Lee, Pavitra Roychoudhury, Roland Schwarzer, Xiaoyu Luo, Steven A Yukl, Sulggi Lee, Rebecca Hoh, Steven G Deeks, R Brad Jones, Marielle Cavrois, Warner C Greene, Nadia R Roan
Published 2020-04-01

Mass Cytometric Analysis of HIV Entry, Replication, and Remodeling in Tissue CD4+ T Cells

by Marielle Cavrois, Trambak Banerjee, Gourab Mukherjee, Nandhini Raman, Rajaa Hussien, Brandon Aguilar Rodriguez, Joshua Vasquez, Matthew H. Spitzer, Nicole H. Lazarus, Jennifer J. Jones, Christina Ochsenbauer, Joseph M. McCune, Eugene C. Butcher, Ann M. Arvin, Nandini Sen, Warner C. Greene, Nadia R. Roan
Published 2017-07-01

The HIV-1 latent reservoir is largely sensitive to circulating T cells

by Joanna A Warren, Shuntai Zhou, Yinyan Xu, Matthew J Moeser, Daniel R MacMillan, Olivia Council, Jennifer Kirchherr, Julia M Sung, Nadia R Roan, Adaora A Adimora, Sarah Joseph, JoAnn D Kuruc, Cynthia L Gay, David M Margolis, Nancie Archin, Zabrina L Brumme, Ronald Swanstrom, Nilu Goonetilleke
Published 2020-10-01

Semen amyloids participate in spermatozoa selection and clearance

by Nadia R Roan, Nathallie Sandi-Monroy, Nargis Kohgadai, Shariq M Usmani, Katherine G Hamil, Jason Neidleman, Mauricio Montano, Ludger Ständker, Annika Röcker, Marielle Cavrois, Jared Rosen, Kara Marson, James F Smith, Christopher D Pilcher, Friedrich Gagsteiger, Olena Sakk, Michael O’Rand, Polina V Lishko, Frank Kirchhoff, Jan Münch, Warner C Greene
Published 2017-06-01

Mucosal stromal fibroblasts markedly enhance HIV infection of CD4+ T cells.

by Jason A Neidleman, Joseph C Chen, Nargis Kohgadai, Janis A Müller, Anders Laustsen, Karthiga Thavachelvam, Karen S Jang, Christina M Stürzel, Jennifer J Jones, Christina Ochsenbauer, Avantika Chitre, Ma Somsouk, Maurice M Garcia, James F Smith, Ruth M Greenblatt, Jan Münch, Martin R Jakobsen, Linda C Giudice, Warner C Greene, Nadia R Roan
Published 2017-02-01

Phenotypic analysis of the unstimulated in vivo HIV CD4 T cell reservoir

by Jason Neidleman, Xiaoyu Luo, Julie Frouard, Guorui Xie, Feng Hsiao, Tongcui Ma, Vincent Morcilla, Ashley Lee, Sushama Telwatte, Reuben Thomas, Whitney Tamaki, Benjamin Wheeler, Rebecca Hoh, Ma Somsouk, Poonam Vohra, Jeffrey Milush, Katherine Sholtis James, Nancie M Archin, Peter W Hunt, Steven G Deeks, Steven A Yukl, Sarah Palmer, Warner C Greene, Nadia R Roan
Published 2020-09-01

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

by Janis A. Müller, Mirja Harms, Franziska Krüger, Rüdiger Groß, Simone Joas, Manuel Hayn, Andrea N. Dietz, Sina Lippold, Jens von Einem, Axel Schubert, Manuela Michel, Benjamin Mayer, Mirko Cortese, Karen S. Jang, Nathallie Sandi-Monroy, Miriam Deniz, Florian Ebner, Olli Vapalahti, Markus Otto, Ralf Bartenschlager, Jean-Philippe Herbeuval, Jonas Schmidt-Chanasit, Nadia R. Roan, Jan Münch
Published 2018-06-01