Pick’s Tau Fibril Shows Multiple Distinct PET Probe Binding Sites: Insights from Computational Modelling

by Sushil K. Mishra, Yoshiki Yamaguchi, Makoto Higuchi, Naruhiko Sahara
Published 2021-12-01

Tau Filaments and the Development of Positron Emission Tomography Tracers

by Michel Goedert, Yoshiki Yamaguchi, Sushil K. Mishra, Makoto Higuchi, Naruhiko Sahara
Published 2018-02-01

Tau Fibril Formation in Cultured Cells Compatible with a Mouse Model of Tauopathy

by Gen Matsumoto, Kazuki Matsumoto, Taeko Kimura, Tetsuya Suhara, Makoto Higuchi, Naruhiko Sahara, Nozomu Mori
Published 2018-05-01

In Vivo Tau Imaging for a Diagnostic Platform of Tauopathy Using the rTg4510 Mouse Line

by Naruhiko Sahara, Masafumi Shimojo, Maiko Ono, Hiroyuki Takuwa, Marcelo Febo, Makoto Higuchi, Tetsuya Suhara
Published 2017-12-01

Neuroprotective effect of mitochondrial translocator protein ligand in a mouse model of tauopathy

by Lauren H. Fairley, Naruhiko Sahara, Ichio Aoki, Bin Ji, Tetsuya Suhara, Makoto Higuchi, Anna M. Barron
Published 2021-03-01

GSK-3beta is required for memory reconsolidation in adult brain.

by Tetsuya Kimura, Shunji Yamashita, Shinobu Nakao, Jung-Mi Park, Miyuki Murayama, Tatsuya Mizoroki, Yuji Yoshiike, Naruhiko Sahara, Akihiko Takashima
Published 2008-01-01

TOC1: A valuable tool in assessing disease progression in the rTg4510 mouse model of tauopathy

by Sarah M. Ward, Diana S. Himmelstein, Yan Ren, Yifan Fu, Xiao-Wen Yu, Kaleigh Roberts, Lester I. Binder, Naruhiko Sahara
Published 2014-07-01

Tau binding protein CAPON induces tau aggregation and neurodegeneration

by Shoko Hashimoto, Yukio Matsuba, Naoko Kamano, Naomi Mihira, Naruhiko Sahara, Jiro Takano, Shin-ichi Muramatsu, Takaomi C. Saido, Takashi Saito
Published 2019-06-01

Author Correction: Tau binding protein CAPON induces tau aggregation and neurodegeneration

by Shoko Hashimoto, Yukio Matsuba, Naoko Kamano, Naomi Mihira, Naruhiko Sahara, Jiro Takano, Shin-ichi Muramatsu, Takaomi C. Saido, Takashi Saito
Published 2019-07-01

Association between Brain and Plasma Glutamine Levels in Healthy Young Subjects Investigated by MRS and LC/MS

by Yuhei Takado, Naoto Sato, Yuta Kanbe, Moyoko Tomiyasu, Lijing Xin, Jamie Near, Kohki Yoshikawa, Naruhiko Sahara, Tatsuya Higashi, Tetsuya Suhara, Makoto Higuchi, Takayuki Obata
Published 2019-07-01

Microglial gene signature reveals loss of homeostatic microglia associated with neurodegeneration of Alzheimer’s disease

by Akira Sobue, Okiru Komine, Yuichiro Hara, Fumito Endo, Hiroyuki Mizoguchi, Seiji Watanabe, Shigeo Murayama, Takashi Saito, Takaomi C. Saido, Naruhiko Sahara, Makoto Higuchi, Tomoo Ogi, Koji Yamanaka
Published 2021-01-01

Differential regional distribution of phosphorylated tau and synapse loss in the nucleus accumbens in tauopathy model mice

by Taiki Kambe, Yumiko Motoi, Ran Inoue, Nobuhiko Kojima, Norihiro Tada, Tetsuya Kimura, Naruhiko Sahara, Shunji Yamashita, Tatsuya Mizoroki, Akihiko Takashima, Kohei Shimada, Koichi Ishiguro, Hiroshi Mizuma, Hirotaka Onoe, Yoshikuni Mizuno, Nobutaka Hattori
Published 2011-06-01

Altered Tau Isoform Ratio Caused by Loss of FUS and SFPQ Function Leads to FTLD-like Phenotypes

by Shinsuke Ishigaki, Yusuke Fujioka, Yohei Okada, Yuichi Riku, Tsuyoshi Udagawa, Daiyu Honda, Satoshi Yokoi, Kuniyuki Endo, Kensuke Ikenaka, Shinnosuke Takagi, Yohei Iguchi, Naruhiko Sahara, Akihiko Takashima, Hideyuki Okano, Mari Yoshida, Hitoshi Warita, Masashi Aoki, Hirohisa Watanabe, Haruo Okado, Masahisa Katsuno, Gen Sobue
Published 2017-01-01