The anti-tubercular activity of simvastatin is mediated by cholesterol-driven autophagy via the AMPK-mTORC1-TFEB axis

by Natalie Bruiners, Noton K. Dutta, Valentina Guerrini, Hugh Salamon, Ken D. Yamaguchi, Petros C. Karakousis, Maria L. Gennaro
Published 2020-12-01

Tuberculosis State Is Associated with Expression of Toll-Like Receptor 2 in Sputum Macrophages

by Karim Lakehal, David Levine, Kathleen F. Kerr, Pooja Vir, Natalie Bruiners, Alfred Lardizabal, Maria Laura Gennaro, Richard Pine, Helene F. Rosenberg
Published 2017-11-01

Human Immunodeficiency Viruses Pseudotyped with SARS-CoV-2 Spike Proteins Infect a Broad Spectrum of Human Cell Lines through Multiple Entry Mechanisms

by Chuan Xu, Annie Wang, Ke Geng, William Honnen, Xuening Wang, Natalie Bruiners, Sukhwinder Singh, Fortunato Ferrara, Sara D’Angelo, Andrew R. M. Bradbury, Maria Laura Gennaro, Dongfang Liu, Abraham Pinter, Theresa L. Chang
Published 2021-05-01

Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific.

by Valentina Guerrini, Brendan Prideaux, Landry Blanc, Natalie Bruiners, Riccardo Arrigucci, Sukhwinder Singh, Hsin Pin Ho-Liang, Hugh Salamon, Pei-Yu Chen, Karim Lakehal, Selvakumar Subbian, Paul O'Brien, Laura E Via, Clifton E Barry, Véronique Dartois, Maria Laura Gennaro
Published 2018-08-01