Major Global Killer Tamed by Hydrogen

by Clifton E. Barry
Published 2015-09-01

Tuberculosis Drug Discovery: A Decade of Hit Assessment for Defined Targets

by Sangmi Oh, Lena Trifonov, Veena D. Yadav, Clifton E. Barry, Helena I. Boshoff
Published 2021-03-01

Fumarate reductase activity maintains an energized membrane in anaerobic Mycobacterium tuberculosis.

by Shinya Watanabe, Michael Zimmermann, Michael B Goodwin, Uwe Sauer, Clifton E Barry, Helena I Boshoff
Published 2011-10-01

Rv2607 from Mycobacterium tuberculosis is a pyridoxine 5'-phosphate oxidase with unusual substrate specificity.

by Ellene H Mashalidis, Tathagata Mukherjee, Paweł Sledź, Dijana Matak-Vinković, Helena Boshoff, Chris Abell, Clifton E Barry
Published 2011-01-01

Chemical constituents and antimycobacterial studies of the leaf extracts of Pavetta crassipes K. Schum

by Nneka N. Ibekwe, Helena Boshoff, Joaquin Randle, Akinbo A. Adesomoju, Clifton E. Barry III, Joseph I. Okogun
Published 2018-04-01

Comparative Evaluation of Sloppy Molecular Beacon and Dual-Labeled Probe Melting Temperature Assays to Identify Mutations in Mycobacterium tuberculosis Resulting in Rifampin, Fluor...

by Sandy S Roh, Laura E Smith, Jong Seok Lee, Laura E Via, Clifton E Barry, David Alland, Soumitesh Chakravorty
Published 2015-01-01

Tuberculosis drugs' distribution and emergence of resistance in patient's lung lesions: A mechanistic model and tool for regimen and dose optimization.

by Natasha Strydom, Sneha V Gupta, William S Fox, Laura E Via, Hyeeun Bang, Myungsun Lee, Seokyong Eum, TaeSun Shim, Clifton E Barry, Matthew Zimmerman, Véronique Dartois, Radojka M Savic
Published 2019-04-01

Evaluating the sensitivity of Mycobacterium tuberculosis to biotin deprivation using regulated gene expression.

by Sae Woong Park, Marcus Klotzsche, Daniel J Wilson, Helena I Boshoff, Hyungjin Eoh, Ujjini Manjunatha, Antje Blumenthal, Kyu Rhee, Clifton E Barry, Courtney C Aldrich, Sabine Ehrt, Dirk Schnappinger
Published 2011-09-01

Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes

by Diego L. Costa, Sivaranjani Namasivayam, Eduardo P. Amaral, Kriti Arora, Alex Chao, Lara R. Mittereder, Mamoudou Maiga, Helena I. Boshoff, Clifton E. Barry, Celia W. Goulding, Bruno B. Andrade, Alan Sher
Published 2016-10-01

Development and Optimization of Chromosomally-Integrated Fluorescent Mycobacterium tuberculosis Reporter Constructs

by Katharina Kolbe, Alice C. Bell, Gareth A. Prosser, Gareth A. Prosser, Maike Assmann, Hee-Jeong Yang, He Eun Forbes, Sophia Gallucci, Katrin D. Mayer-Barber, Helena I. Boshoff, Clifton E. Barry III
Published 2020-12-01

NOS2-deficient mice with hypoxic necrotizing lung lesions predict outcomes of tuberculosis chemotherapy in humans

by Martin Gengenbacher, Maria A. Duque-Correa, Peggy Kaiser, Stefanie Schuerer, Doris Lazar, Ulrike Zedler, Stephen T. Reece, Amit Nayyar, Stewart T. Cole, Vadim Makarov, Clifton E. Barry III, Véronique Dartois, Stefan H. E. Kaufmann
Published 2017-08-01

Bacterial Loads Measured by the Xpert MTB/RIF Assay as Markers of Culture Conversion and Bacteriological Cure in Pulmonary TB.

by Shubhada Shenai, Katharina Ronacher, Stefanus Malherbe, Kim Stanley, Magdalena Kriel, Jill Winter, Thomas Peppard, Charles E Barry, Jing Wang, Lori E Dodd, Laura E Via, Clifton E Barry, Gerhard Walzl, David Alland
Published 2016-01-01

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis.

by Suresh B Lakshminarayana, Helena I M Boshoff, Joseph Cherian, Sindhu Ravindran, Anne Goh, Jan Jiricek, Mahesh Nanjundappa, Amit Nayyar, Meera Gurumurthy, Ramandeep Singh, Thomas Dick, Francesca Blasco, Clifton E Barry, Paul C Ho, Ujjini H Manjunatha
Published 2014-01-01

Impact of diabetes and smoking on mortality in tuberculosis.

by George W Reed, Hongjo Choi, So Young Lee, Myungsun Lee, Youngran Kim, Hyemi Park, Jongseok Lee, Xin Zhan, Hyeungseok Kang, SooHee Hwang, Matthew Carroll, Ying Cai, Sang-Nae Cho, Clifton E Barry, Laura E Via, Hardy Kornfeld
Published 2013-01-01

Storage lipid studies in tuberculosis reveal that foam cell biogenesis is disease-specific.

by Valentina Guerrini, Brendan Prideaux, Landry Blanc, Natalie Bruiners, Riccardo Arrigucci, Sukhwinder Singh, Hsin Pin Ho-Liang, Hugh Salamon, Pei-Yu Chen, Karim Lakehal, Selvakumar Subbian, Paul O'Brien, Laura E Via, Clifton E Barry, Véronique Dartois, Maria Laura Gennaro
Published 2018-08-01

Real-Time Investigation of Tuberculosis Transmission: Developing the Respiratory Aerosol Sampling Chamber (RASC).

by Robin Wood, Carl Morrow, Clifton E Barry, Wayne A Bryden, Charles J Call, Anthony J Hickey, Charles E Rodes, Thomas J Scriba, Jonathan Blackburn, Chacha Issarow, Nicola Mulder, Jeremy Woodward, Atica Moosa, Vinayak Singh, Valerie Mizrahi, Digby F Warner
Published 2016-01-01

Linezolid Trough Concentrations Correlate with Mitochondrial Toxicity-Related Adverse Events in the Treatment of Chronic Extensively Drug-Resistant Tuberculosis

by Taeksun Song, Myungsun Lee, Han-Seung Jeon, Yumi Park, Lori E. Dodd, Véronique Dartois, Dean Follman, Jing Wang, Ying Cai, Lisa C. Goldfeder, Kenneth N. Olivier, Yingda Xie, Laura E. Via, Sang Nae Cho, Clifton E. Barry III, Ray Y. Chen
Published 2015-11-01

Identification of new drug targets and resistance mechanisms in Mycobacterium tuberculosis.

by Thomas R Ioerger, Theresa O'Malley, Reiling Liao, Kristine M Guinn, Mark J Hickey, Nilofar Mohaideen, Kenan C Murphy, Helena I M Boshoff, Valerie Mizrahi, Eric J Rubin, Christopher M Sassetti, Clifton E Barry, David R Sherman, Tanya Parish, James C Sacchettini
Published 2013-01-01

The within-host population dynamics of Mycobacterium tuberculosis vary with treatment efficacy

by Andrej Trauner, Qingyun Liu, Laura E. Via, Xin Liu, Xianglin Ruan, Lili Liang, Huimin Shi, Ying Chen, Ziling Wang, Ruixia Liang, Wei Zhang, Wang Wei, Jingcai Gao, Gang Sun, Daniela Brites, Kathleen England, Guolong Zhang, Sebastien Gagneux, Clifton E. Barry, Qian Gao
Published 2017-04-01

A semi-automatic technique to quantify complex tuberculous lung lesions on 18F-fluorodeoxyglucose positron emission tomography/computerised tomography images

by Stephanus T. Malherbe, Patrick Dupont, Ilse Kant, Petri Ahlers, Magdalena Kriel, André G. Loxton, Ray Y. Chen, Laura E. Via, Friedrich Thienemann, Robert J. Wilkinson, Clifton E. Barry, Stephanie Griffith-Richards, Annare Ellman, Katharina Ronacher, Jill Winter, Gerhard Walzl, James M. Warwick, the Catalysis Biomarker Consortium
Published 2018-06-01