R pyocin tail fiber structure reveals a receptor-binding domain with a lectin fold.

by Adam J Salazar, Mukul Sherekar, Jennifer Tsai, James C Sacchettini
Published 2019-01-01

Development of single-cell-level microfluidic technology for long-term growth visualization of living cultures of Mycobacterium smegmatis

by Han Wang, Gloria M. Conover, Song-I Han, James C. Sacchettini, Arum Han
Published 2021-05-01

The molecular basis of pyrazinamide activity on Mycobacterium tuberculosis PanD

by Qingan Sun, Xiaojun Li, Lisa M. Perez, Wanliang Shi, Ying Zhang, James C. Sacchettini
Published 2020-01-01

A low-cost, novel endoscopic repeated-access port for small animal research

by Shannon N. Ingram, Andrew B. Robbins, Stacy J. Gillenwater, Vince Gresham, James C. Sacchettini, Michael R. Moreno
Published 2020-01-01

A vitamin B12 transporter in Mycobacterium tuberculosis

by Krishnamoorthy Gopinath, Česlovas Venclovas, Thomas R. Ioerger, James C. Sacchettini, John D. McKinney, Valerie Mizrahi, Digby F. Warner
Published 2013-01-01

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis.

by Yanjia J Zhang, Thomas R Ioerger, Curtis Huttenhower, Jarukit E Long, Christopher M Sassetti, James C Sacchettini, Eric J Rubin
Published 2012-09-01

High Throughput Screen for Escherichia coli Twin Arginine Translocation (Tat) Inhibitors.

by Umesh K Bageshwar, Lynn VerPlank, Dwight Baker, Wen Dong, Shruthi Hamsanathan, Neal Whitaker, James C Sacchettini, Siegfried M Musser
Published 2016-01-01

Correction: Global Assessment of Genomic Regions Required for Growth in.

by Yanjia J. Zhang, Thomas R. Ioerger, Curtis Huttenhower, Jarukit E. Long, Christopher M. Sassetti, James C. Sacchettini, Eric J. Rubin
Published 2013-07-01

Mycobacterium tuberculosis SatS is a chaperone for the SecA2 protein export pathway

by Brittany K Miller, Ryan Hughes, Lauren S Ligon, Nathan W Rigel, Seidu Malik, Brandon R Anjuwon-Foster, James C Sacchettini, Miriam Braunstein
Published 2019-01-01

Novel transthyretin amyloid fibril formation inhibitors: synthesis, biological evaluation, and X-ray structural analysis.

by Satheesh K Palaninathan, Nilofar N Mohamedmohaideen, Elisabetta Orlandini, Gabriella Ortore, Susanna Nencetti, Annalina Lapucci, Armando Rossello, Joel S Freundlich, James C Sacchettini
Published 2009-07-01

A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide

by Adam N. Yadon, Kashmeel Maharaj, John H. Adamson, Yi-Pin Lai, James C. Sacchettini, Thomas R. Ioerger, Eric J. Rubin, Alexander S. Pym
Published 2017-09-01

Thiacetazone, an antitubercular drug that inhibits cyclopropanation of cell wall mycolic acids in mycobacteria.

by Anuradha Alahari, Xavier Trivelli, Yann Guérardel, Lynn G Dover, Gurdyal S Besra, James C Sacchettini, Robert C Reynolds, Geoffrey D Coxon, Laurent Kremer
Published 2007-12-01

High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria.

by Nqobile A C Ngubane, Lionel Gresh, Thomas R Ioerger, James C Sacchettini, Yanjia J Zhang, Eric J Rubin, Alexander Pym, Makobetsa Khati
Published 2013-01-01

Functional genomics screening utilizing mutant mouse embryonic stem cells identifies novel radiation-response genes.

by Kimberly Loesch, Stacy Galaviz, Zaher Hamoui, Ryan Clanton, Gamal Akabani, Michael Deveau, Michael DeJesus, Thomas Ioerger, James C Sacchettini, Deeann Wallis
Published 2015-01-01

Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa.

by Thomas R Ioerger, Sunwoo Koo, Eun-Gyu No, Xiaohua Chen, Michelle H Larsen, William R Jacobs, Manormoney Pillay, A Willem Sturm, James C Sacchettini
Published 2009-11-01

Aspartate aminotransferase Rv3722c governs aspartate-dependent nitrogen metabolism in Mycobacterium tuberculosis

by Robert S. Jansen, Lungelo Mandyoli, Ryan Hughes, Shoko Wakabayashi, Jessica T. Pinkham, Bruna Selbach, Kristine M. Guinn, Eric J. Rubin, James C. Sacchettini, Kyu Y. Rhee
Published 2020-04-01

Subfamily-specific adaptations in the structures of two penicillin-binding proteins from Mycobacterium tuberculosis.

by Daniil M Prigozhin, Inna V Krieger, John P Huizar, Daniela Mavrici, Geoffrey S Waldo, Li-Wei Hung, James C Sacchettini, Thomas C Terwilliger, Tom Alber
Published 2014-01-01

Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2019-06-01

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2018-03-01

Identification of cyclic hexapeptides natural products with inhibitory potency against Mycobacterium tuberculosis

by Sheo B. Singh, Joshua Odingo, Mai A. Bailey, Bjorn Sunde, Aaron Korkegian, Theresa O’Malley, Yulia Ovechkina, Thomas R. Ioerger, James C. Sacchettini, Katherine Young, David B. Olsen, Tanya Parish
Published 2018-06-01