Exploiting Homoplasy in Genome-Wide Association Studies to Enhance Identification of Antibiotic-Resistance Mutations in Bacterial Genomes

by Yi-Pin Lai, Thomas R Ioerger
Published 2020-07-01

A statistical method to identify recombination in bacterial genomes based on SNP incompatibility

by Yi-Pin Lai, Thomas R. Ioerger
Published 2018-11-01

Mycobacterium smegmatis HtrA Blocks the Toxic Activity of a Putative Cell Wall Amidase

by Katherine J. Wu, Cara C. Boutte, Thomas R. Ioerger, Eric J. Rubin
Published 2019-05-01

TRANSIT--A Software Tool for Himar1 TnSeq Analysis.

by Michael A DeJesus, Chaitra Ambadipudi, Richard Baker, Christopher Sassetti, Thomas R Ioerger
Published 2015-10-01

Comprehensive analysis of iron utilization by Mycobacterium tuberculosis.

by Lei Zhang, R Curtis Hendrickson, Virginia Meikle, Elliot J Lefkowitz, Thomas R Ioerger, Michael Niederweis
Published 2020-02-01

Altered Mycobacterium tuberculosis Cell Wall Metabolism and Physiology Associated With RpoB Mutation H526D

by Victoria L. Campodónico, Dalin Rifat, Yu-Min Chuang, Thomas R. Ioerger, Petros C. Karakousis, Petros C. Karakousis
Published 2018-03-01

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism.

by Jennifer E Griffin, Jeffrey D Gawronski, Michael A Dejesus, Thomas R Ioerger, Brian J Akerley, Christopher M Sassetti
Published 2011-09-01

Distinct Bacterial Pathways Influence the Efficacy of Antibiotics against Mycobacterium tuberculosis

by Michelle M. Bellerose, Megan K. Proulx, Clare M. Smith, Richard E. Baker, Thomas R. Ioerger, Christopher M. Sassetti
Published 2020-08-01

A vitamin B12 transporter in Mycobacterium tuberculosis

by Krishnamoorthy Gopinath, Česlovas Venclovas, Thomas R. Ioerger, James C. Sacchettini, John D. McKinney, Valerie Mizrahi, Digby F. Warner
Published 2013-01-01

Global assessment of genomic regions required for growth in Mycobacterium tuberculosis.

by Yanjia J Zhang, Thomas R Ioerger, Curtis Huttenhower, Jarukit E Long, Christopher M Sassetti, James C Sacchettini, Eric J Rubin
Published 2012-09-01

Correction: Global Assessment of Genomic Regions Required for Growth in.

by Yanjia J. Zhang, Thomas R. Ioerger, Curtis Huttenhower, Jarukit E. Long, Christopher M. Sassetti, James C. Sacchettini, Eric J. Rubin
Published 2013-07-01

A comprehensive characterization of PncA polymorphisms that confer resistance to pyrazinamide

by Adam N. Yadon, Kashmeel Maharaj, John H. Adamson, Yi-Pin Lai, James C. Sacchettini, Thomas R. Ioerger, Eric J. Rubin, Alexander S. Pym
Published 2017-09-01

High-throughput sequencing enhanced phage display identifies peptides that bind mycobacteria.

by Nqobile A C Ngubane, Lionel Gresh, Thomas R Ioerger, James C Sacchettini, Yanjia J Zhang, Eric J Rubin, Alexander Pym, Makobetsa Khati
Published 2013-01-01

Genome analysis of multi- and extensively-drug-resistant tuberculosis from KwaZulu-Natal, South Africa.

by Thomas R Ioerger, Sunwoo Koo, Eun-Gyu No, Xiaohua Chen, Michelle H Larsen, William R Jacobs, Manormoney Pillay, A Willem Sturm, James C Sacchettini
Published 2009-11-01

Statistical analysis of variability in TnSeq data across conditions using zero-inflated negative binomial regression

by Siddharth Subramaniyam, Michael A. DeJesus, Anisha Zaveri, Clare M. Smith, Richard E. Baker, Sabine Ehrt, Dirk Schnappinger, Christopher M. Sassetti, Thomas R. Ioerger
Published 2019-11-01

Correction: TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2019-06-01

TnSeq of Mycobacterium tuberculosis clinical isolates reveals strain-specific antibiotic liabilities.

by Allison F Carey, Jeremy M Rock, Inna V Krieger, Michael R Chase, Marta Fernandez-Suarez, Sebastien Gagneux, James C Sacchettini, Thomas R Ioerger, Sarah M Fortune
Published 2018-03-01

Global Assessment of Mycobacterium avium subsp. hominissuis Genetic Requirement for Growth and Virulence

by Marte S. Dragset, Thomas R. Ioerger, Maja Loevenich, Markus Haug, Niruja Sivakumar, Anne Marstad, Pere Joan Cardona, Geir Klinkenberg, Eric J. Rubin, Magnus Steigedal, Trude H. Flo
Published 2019-12-01

A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis

by Cara C Boutte, Christina E Baer, Kadamba Papavinasasundaram, Weiru Liu, Michael R Chase, Xavier Meniche, Sarah M Fortune, Christopher M Sassetti, Thomas R Ioerger, Eric J Rubin
Published 2016-06-01

Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis.

by Hendrik Koliwer-Brandl, Karl Syson, Robert van de Weerd, Govind Chandra, Ben Appelmelk, Marina Alber, Thomas R Ioerger, William R Jacobs, Jeroen Geurtsen, Stephen Bornemann, Rainer Kalscheuer
Published 2016-08-01