Peptides derived from cadherin juxtamembrane region inhibit platelet function

by Kalyan Golla, Ilias Stavropoulos, Denis C. Shields, Niamh Moran
Published 2018-01-01

The Role of Platelet-Derived ADP and ATP in Promoting Pancreatic Cancer Cell Survival and Gemcitabine Resistance

by Omar Elaskalani, Marco Falasca, Niamh Moran, Michael C. Berndt, Pat Metharom
Published 2017-10-01

Discovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergies.

by Federica Lombardi, Kalyan Golla, Darren J Fitzpatrick, Fergal P Casey, Niamh Moran, Denis C Shields
Published 2015-04-01

Poly(Ethylene Glycol)-Based Backbones with High Peptide Loading Capacities

by Aoife O'Connor, Jean-Noel Marsat, Annachiara Mitrugno, Tom Flahive, Niamh Moran, David Brayden, Marc Devocelle
Published 2014-10-01

Computational and experimental analysis of bioactive peptide linear motifs in the integrin adhesome.

by Kevin T O'Brien, Kalyan Golla, Tilen Kranjc, Darragh O'Donovan, Seamus Allen, Patricia Maguire, Jeremy C Simpson, David O'Connell, Niamh Moran, Denis C Shields
Published 2019-01-01

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.

by Daniel K Shanley, Patrick A Kiely, Kalyan Golla, Seamus Allen, Kenneth Martin, Ronan T O'Riordan, Melanie Ball, John D Aplin, Bernhard B Singer, Noel Caplice, Niamh Moran, Tom Moore
Published 2013-01-01

COVID-19 induces a hyperactive phenotype in circulating platelets.

by Shane P Comer, Sarah Cullivan, Paulina B Szklanna, Luisa Weiss, Steven Cullen, Sarah Kelliher, Albert Smolenski, Claire Murphy, Haidar Altaie, John Curran, Katherine O'Reilly, Aoife G Cotter, Brian Marsh, Sean Gaine, Patrick Mallon, Brian McCullagh, Niamh Moran, Fionnuala Ní Áinle, Barry Kevane, Patricia B Maguire, COCOON Study investigators
Published 2021-02-01