Size Matters: The Functional Role of the CEACAM1 Isoform Signature and Its Impact for NK Cell-Mediated Killing in Melanoma

by Iris Helfrich, Bernhard B. Singer
Published 2019-03-01

Cold storage of rat hepatocyte suspensions for one week in a customized cold storage solution--preservation of cell attachment and metabolism.

by Gesine Pless-Petig, Bernhard B Singer, Ursula Rauen
Published 2012-01-01

Deregulation of the CEACAM expression pattern causes undifferentiated cell growth in human lung adenocarcinoma cells.

by Bernhard B Singer, Inka Scheffrahn, Robert Kammerer, Norbert Suttorp, Suleyman Ergun, Hortense Slevogt
Published 2010-01-01

Fusobacterium nucleatum supresses anti-tumor immunity by activating CEACAM1

by Chamutal Gur, Naseem Maalouf, Amjad Shhadeh, Orit Berhani, Bernhard B. Singer, Gilad Bachrach, Ofer Mandelboim
Published 2019-06-01

Fusobacterium spp. target human CEACAM1 via the trimeric autotransporter adhesin CbpF

by Matthew L. Brewer, David Dymock, R. Leo Brady, Bernhard B. Singer, Mumtaz Virji, Darryl J. Hill
Published 2019-01-01

The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells.

by Jaroslaw Thomas Dankert, Marc Wiesehöfer, Elena Dilara Czyrnik, Bernhard B Singer, Nicola von Ostau, Gunther Wennemuth
Published 2018-01-01

Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.

by Harrison T Muturi, Janine D Dreesen, Elena Nilewski, Holger Jastrow, Bernd Giebel, Suleyman Ergun, Bernhard B Singer
Published 2013-01-01

The Helicobacter pylori HopQ outermembrane protein inhibits immune cell activities

by Chamutal Gur, Naseem Maalouf, Markus Gerhard, Bernhard B. Singer, Johanna Emgård, Violeta Temper, Tzahi Neuman, Ofer Mandelboim, Gilad Bachrach
Published 2019-04-01

Engagement of CEACAM1 by <i>Helicobacter</i> <i>pylori</i> HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells

by Karin Taxauer, Youssef Hamway, Anna Ralser, Alisa Dietl, Karin Mink, Michael Vieth, Bernhard B. Singer, Markus Gerhard, Raquel Mejías-Luque
Published 2021-08-01

Extracellular Chromatin Triggers Release of Soluble CEACAM8 Upon Activation of Neutrophils

by Matthieu Ribon, Matthieu Ribon, Julie Mussard, Julie Mussard, Luca Semerano, Luca Semerano, Luca Semerano, Bernhard B. Singer, Patrice Decker, Patrice Decker
Published 2019-06-01

Cysteine Residues in <i>Helicobacter pylori</i> Adhesin HopQ are Required for CEACAM–HopQ Interaction and Subsequent CagA Translocation

by Youssef Hamway, Karin Taxauer, Kristof Moonens, Victoria Neumeyer, Wolfgang Fischer, Verena Schmitt, Bernhard B. Singer, Han Remaut, Markus Gerhard, Raquel Mejías-Luque
Published 2020-03-01

Type IV secretion of Helicobacter pylori CagA into oral epithelial cells is prevented by the absence of CEACAM receptor expression

by Nicole Tegtmeyer, Tabita Denisia Ghete, Verena Schmitt, Torsten Remmerbach, Maria Celeste C. Cortes, Edgardo M. Bondoc, Hans-Ludwig Graf, Bernhard B. Singer, Christian Hirsch, Steffen Backert
Published 2020-05-01

Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation

by Johanna Galaski, Johanna Galaski, Amjad Shhadeh, Ariana Umaña, Christopher C. Yoo, Ludovica Arpinati, Batya Isaacson, Orit Berhani, Bernhard B. Singer, Daniel J. Slade, Gilad Bachrach, Ofer Mandelboim
Published 2021-07-01

CEACAM1 regulates CD8+ T cell immunity and protects from severe pathology during Citrobacter rodentium induced colitis

by Julia Zöller, Jana-Fabienne Ebel, Vishal Khairnar, Verena Schmitt, Robert Klopfleisch, Jana Meiners, Virginia Seiffart, Wiebke Hansen, Jan Buer, Bernhard B. Singer, Karl S. Lang, Astrid M. Westendorf
Published 2020-11-01

Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.

by Bernhard B Singer, Lena Opp, Annina Heinrich, Frauke Schreiber, Ramona Binding-Liermann, Luis Carlos Berrocal-Almanza, Kerstin A Heyl, Mario M Müller, Andreas Weimann, Janine Zweigner, Hortense Slevogt
Published 2014-01-01

Pregnancy-specific glycoproteins bind integrin αIIbβ3 and inhibit the platelet-fibrinogen interaction.

by Daniel K Shanley, Patrick A Kiely, Kalyan Golla, Seamus Allen, Kenneth Martin, Ronan T O'Riordan, Melanie Ball, John D Aplin, Bernhard B Singer, Noel Caplice, Niamh Moran, Tom Moore
Published 2013-01-01

Fluorophore-conjugated Helicobacter pylori recombinant membrane protein (HopQ) labels primary colon cancer and metastases in orthotopic mouse models by binding CEA-related cell adh...

by Hannah M. Hollandsworth, Verena Schmitt, Siamak Amirfakhri, Filemoni Filemoni, Alexej Schmidt, Maréne Landström, Mykola Lyndin, Steffen Backert, Markus Gerhard, Gunther Wennemuth, Robert M. Hoffman, Bernhard B. Singer, Michael Bouvet
Published 2020-12-01

Binding of Candida albicans to Human CEACAM1 and CEACAM6 Modulates the Inflammatory Response of Intestinal Epithelial Cells

by Esther Klaile, Mario M. Muller, Miriam R. Schafer, Ann-Katrin Clauder, Sabina Feer, Kerstin A. Heyl, Magdalena Stock, Tilman E. Klassert, Peter F. Zipfel, Bernhard B. Singer, Hortense Slevogt, Michael Lorenz
Published 2017-03-01

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection

by Vishal Khairnar, Vikas Duhan, Ashwini M. Patil, Fan Zhou, Hilal Bhat, Christine Thoens, Piyush Sharma, Tom Adomati, Sarah-Kim Friendrich, Judith Bezgovsek, Janine D. Dreesen, Gunther Wennemuth, Astrid M. Westendorf, Gennadiy Zelinskyy, Ulf Dittmer, Cornelia Hardt, Jörg Timm, Joachim R. Göthert, Philipp A. Lang, Bernhard B. Singer, Karl S. Lang
Published 2018-07-01

Unaltered Fungal Burden and Lethality in Human CEACAM1-Transgenic Mice During Candida albicans Dissemination and Systemic Infection

by Esther Klaile, Mario M. Müller, Cristina Zubiría-Barrera, Saskia Brehme, Tilman E. Klassert, Magdalena Stock, Adrian Durotin, Tien D. Nguyen, Sabina Feer, Bernhard B. Singer, Peter F. Zipfel, Peter F. Zipfel, Sven Rudolphi, Sven Rudolphi, Sven Rudolphi, Ilse D. Jacobsen, Ilse D. Jacobsen, Ilse D. Jacobsen, Hortense Slevogt
Published 2019-11-01