Celebrating 20 Years of IGHV Mutation Analysis in CLL

by Nicholas Chiorazzi, Freda K. Stevenson
Published 2020-02-01

AID in Chronic Lymphocytic Leukemia: Induction and Action During Disease Progression

by Pablo Oppezzo, Marcelo Navarrete, Nicholas Chiorazzi
Published 2021-05-01

AID Overlapping and Polη Hotspots Are Key Features of Evolutionary Variation Within the Human Antibody Heavy Chain (IGHV) Genes

by Catherine Tang, Davide Bagnara, Davide Bagnara, Nicholas Chiorazzi, Matthew D. Scharff, Thomas MacCarthy
Published 2020-04-01

A Detailed Analysis of Parameters Supporting the Engraftment and Growth of Chronic Lymphocytic Leukemia Cells in Immune-Deficient Mice

by Piers E. M. Patten, Piers E. M. Patten, Gerardo Ferrer, Shih-Shih Chen, Jonathan E. Kolitz, Jonathan E. Kolitz, Kanti R. Rai, Kanti R. Rai, Steven L. Allen, Steven L. Allen, Jacqueline C. Barrientos, Jacqueline C. Barrientos, Nikolaos Ioannou, Alan G. Ramsay, Nicholas Chiorazzi, Nicholas Chiorazzi, Nicholas Chiorazzi
Published 2021-03-01

The Number of Overlapping AID Hotspots in Germline IGHV Genes Is Inversely Correlated with Mutation Frequency in Chronic Lymphocytic Leukemia.

by Chaohui Yuan, Charles C Chu, Xiao-Jie Yan, Davide Bagnara, Nicholas Chiorazzi, Thomas MacCarthy
Published 2017-01-01

Novel Method for High-Throughput Full-Length IGHV-D-J Sequencing of the Immune Repertoire from Bulk B-Cells with Single-Cell Resolution

by Stefano Vergani, Stefano Vergani, Ilya Korsunsky, Andrea Nicola Mazzarello, Gerardo Ferrer, Nicholas Chiorazzi, Davide Bagnara, Davide Bagnara
Published 2017-09-01

Binding of CLL Subset 4 B Cell Receptor Immunoglobulins to Viable Human Memory B Lymphocytes Requires a Distinctive IGKV Somatic Mutation

by Rosa Catera, Yun Liu, Chao Gao, Xiao-Jie Yan, Amanda Magli, Steven L. Allen, Jonathan E. Kolitz, Kanti R. Rai, Charles C. Chu, Ten Feizi, Kostas Stamatopoulos, Nicholas Chiorazzi
Published 2017-01-01

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia

by Claudia Minici, Maria Gounari, Rudolf Übelhart, Lydia Scarfò, Marcus Dühren-von Minden, Dunja Schneider, Alpaslan Tasdogan, Alabbas Alkhatib, Andreas Agathangelidis, Stavroula Ntoufa, Nicholas Chiorazzi, Hassan Jumaa, Kostas Stamatopoulos, Paolo Ghia, Massimo Degano
Published 2017-06-01

Post-Transformation IGHV-IGHD-IGHJ Mutations in Chronic Lymphocytic Leukemia B Cells: Implications for Mutational Mechanisms and Impact on Clinical Course

by Davide Bagnara, Davide Bagnara, Catherine Tang, Jennifer R. Brown, Siddha Kasar, Stacey Fernandes, Monica Colombo, Stefano Vergani, Andrea N. Mazzarello, Fabio Ghiotto, Fabio Ghiotto, Silvia Bruno, Fortunato Morabito, Fortunato Morabito, Kanti R. Rai, Kanti R. Rai, Jonathan E. Kolitz, Jonathan E. Kolitz, Jacqueline C. Barrientos, Jacqueline C. Barrientos, Steven L. Allen, Steven L. Allen, Franco Fais, Franco Fais, Matthew D. Scharff, Thomas MacCarthy, Nicholas Chiorazzi, Nicholas Chiorazzi
Published 2021-05-01

Automated shape-based clustering of 3D immunoglobulin protein structures in chronic lymphocytic leukemia

by Eleftheria Polychronidou, Ilias Kalamaras, Andreas Agathangelidis, Lesley-Ann Sutton, Xiao-Jie Yan, Vasilis Bikos, Anna Vardi, Konstantinos Mochament, Nicholas Chiorazzi, Chrysoula Belessi, Richard Rosenquist, Paolo Ghia, Kostas Stamatopoulos, Panayiotis Vlamos, Anna Chailyan, Nanna Overby, Paolo Marcatili, Anastasia Hatzidimitriou, Dimitrios Tzovaras
Published 2018-11-01

IGHV1-69 B cell chronic lymphocytic leukemia antibodies cross-react with HIV-1 and hepatitis C virus antigens as well as intestinal commensal bacteria.

by Kwan-Ki Hwang, Ashley M Trama, Daniel M Kozink, Xi Chen, Kevin Wiehe, Abby J Cooper, Shi-Mao Xia, Minyue Wang, Dawn J Marshall, John Whitesides, Munir Alam, Georgia D Tomaras, Steven L Allen, Kanti R Rai, Jane McKeating, Rosa Catera, Xiao-Jie Yan, Charles C Chu, Garnett Kelsoe, Hua-Xin Liao, Nicholas Chiorazzi, Barton F Haynes
Published 2014-01-01