Informatics and Computational Methods in Natural Product Drug Discovery: A Review and Perspectives

by Joseph D. Romano, Joseph D. Romano, Joseph D. Romano, Joseph D. Romano, Nicholas P. Tatonetti, Nicholas P. Tatonetti, Nicholas P. Tatonetti, Nicholas P. Tatonetti
Published 2019-04-01

Using Machine Learning to Identify Adverse Drug Effects Posing Increased Risk to Women

by Payal Chandak, Nicholas P. Tatonetti
Published 2020-10-01

Evaluating risk detection methods to uncover ontogenic-mediated adverse drug effect mechanisms in children

by Nicholas P. Giangreco, Nicholas P. Tatonetti
Published 2021-07-01

Associations between blood type and COVID-19 infection, intubation, and death

by Michael Zietz, Jason Zucker, Nicholas P. Tatonetti
Published 2020-11-01

Connectivity Homology Enables Inter-Species Network Models of Synthetic Lethality.

by Alexandra Jacunski, Scott J Dixon, Nicholas P Tatonetti
Published 2015-10-01

Ten Simple Rules to Enable Multi-site Collaborations through Data Sharing.

by Mary Regina Boland, Konrad J Karczewski, Nicholas P Tatonetti
Published 2017-01-01

Improving Detection of Arrhythmia Drug-Drug Interactions in Pharmacovigilance Data through the Implementation of Similarity-Based Modeling.

by Santiago Vilar, Tal Lorberbaum, George Hripcsak, Nicholas P Tatonetti
Published 2015-01-01

Climate Classification is an Important Factor in Assessing Quality-of-Care Across Hospitals

by Mary Regina Boland, Pradipta Parhi, Pierre Gentine, Nicholas P. Tatonetti
Published 2017-07-01

Tissue‐Specific Analysis of Pharmacological Pathways

by Yun Hao, Kayla Quinnies, Ronald Realubit, Charles Karan, Nicholas P. Tatonetti
Published 2018-07-01

Detection of drug-drug interactions by modeling interaction profile fingerprints.

by Santiago Vilar, Eugenio Uriarte, Lourdes Santana, Nicholas P Tatonetti, Carol Friedman
Published 2013-01-01

Coherent functional modules improve transcription factor target identification, cooperativity prediction, and disease association.

by Konrad J Karczewski, Michael Snyder, Russ B Altman, Nicholas P Tatonetti
Published 2014-02-01

Comparative analysis, applications, and interpretation of electronic health record-based stroke phenotyping methods

by Phyllis M. Thangaraj, Benjamin R. Kummer, Tal Lorberbaum, Mitchell S. V. Elkind, Nicholas P. Tatonetti
Published 2020-12-01

STORMSeq: an open-source, user-friendly pipeline for processing personal genomics data in the cloud.

by Konrad J Karczewski, Guy Haskin Fernald, Alicia R Martin, Michael Snyder, Nicholas P Tatonetti, Joel T Dudley
Published 2014-01-01

Predicting Phenotypic Polymyxin Resistance in Klebsiella pneumoniae through Machine Learning Analysis of Genomic Data

by Nenad Macesic, Oliver J. Bear Don’t Walk, Itsik Pe’er, Nicholas P. Tatonetti, Anton Y. Peleg, Anne-Catrin Uhlemann
Published 2020-05-01

A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors

by Kaitlyn M. Gayvert, Etienne Dardenne, Cynthia Cheung, Mary Regina Boland, Tal Lorberbaum, Jackline Wanjala, Yu Chen, Mark A. Rubin, Nicholas P. Tatonetti, David S. Rickman, Olivier Elemento
Published 2016-06-01

Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis

by Scott J Dixon, Darpan N Patel, Matthew Welsch, Rachid Skouta, Eric D Lee, Miki Hayano, Ajit G Thomas, Caroline E Gleason, Nicholas P Tatonetti, Barbara S Slusher, Brent R Stockwell
Published 2014-05-01

Longitudinal profiling of circulating miRNA during cardiac allograft rejection: a proof‐of‐concept study

by Peter J. Kennel, Alexandre Yahi, Yoshifumi Naka, Donna M. Mancini, Charles C. Marboe, Klaas Max, Kemal Akat, Thomas Tuschl, Elena‐Rodica M. Vasilescu, Emmanuel Zorn, Nicholas P. Tatonetti, Paul Christian Schulze
Published 2021-06-01

Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining

by Khader Shameer, M. Mercedes Perez-Rodriguez, Roy Bachar, Li Li, Amy Johnson, Kipp W. Johnson, Benjamin S. Glicksberg, Milo R. Smith, Ben Readhead, Joseph Scarpa, Jebakumar Jebakaran, Patricia Kovatch, Sabina Lim, Wayne Goodman, David L. Reich, Andrew Kasarskis, Nicholas P. Tatonetti, Joel T. Dudley
Published 2018-09-01

Genome wide analysis of drug-induced torsades de pointes: lack of common variants with large effect sizes.

by Elijah R Behr, Marylyn D Ritchie, Toshihiro Tanaka, Stefan Kääb, Dana C Crawford, Paola Nicoletti, Aris Floratos, Moritz F Sinner, Prince J Kannankeril, Arthur A M Wilde, Connie R Bezzina, Eric Schulze-Bahr, Sven Zumhagen, Pascale Guicheney, Nanette H Bishopric, Vanessa Marshall, Saad Shakir, Chrysoula Dalageorgou, Steve Bevan, Yalda Jamshidi, Rachel Bastiaenen, Robert J Myerburg, Jean-Jacques Schott, A John Camm, Gerhard Steinbeck, Kris Norris, Russ B Altman, Nicholas P Tatonetti, Steve Jeffery, Michiaki Kubo, Yusuke Nakamura, Yufeng Shen, Alfred L George, Dan M Roden
Published 2013-01-01

Medical records-based chronic kidney disease phenotype for clinical care and “big data” observational and genetic studies

by Ning Shang, Atlas Khan, Fernanda Polubriaginof, Francesca Zanoni, Karla Mehl, David Fasel, Paul E. Drawz, Robert J. Carrol, Joshua C. Denny, Matthew A. Hathcock, Adelaide M. Arruda-Olson, Peggy L. Peissig, Richard A. Dart, Murray H. Brilliant, Eric B. Larson, David S. Carrell, Sarah Pendergrass, Shefali Setia Verma, Marylyn D. Ritchie, Barbara Benoit, Vivian S. Gainer, Elizabeth W. Karlson, Adam S. Gordon, Gail P. Jarvik, Ian B. Stanaway, David R. Crosslin, Sumit Mohan, Iuliana Ionita-Laza, Nicholas P. Tatonetti, Ali G. Gharavi, George Hripcsak, Chunhua Weng, Krzysztof Kiryluk
Published 2021-04-01