A diverse collection of B cells responded to HIV infection in infant BG505

by Cassandra Simonich, Mackenzie M. Shipley, Laura Doepker, Theodore Gobillot, Meghan Garrett, Evan M. Cale, Brianna Hennessy, Hannah Itell, Vrasha Chohan, Nicole Doria-Rose, Ruth Nduati, Julie Overbaugh
Published 2021-06-01

Structural Constraints at the Trimer Apex Stabilize the HIV-1 Envelope in a Closed, Antibody-Protected Conformation

by Christina Guzzo, Peng Zhang, Qingbo Liu, Alice L. Kwon, Ferzan Uddin, Alexandra I. Wells, Hana Schmeisser, Raffaello Cimbro, Jinghe Huang, Nicole Doria-Rose, Stephen D. Schmidt, Michael A. Dolan, Mark Connors, John R. Mascola, Paolo Lusso
Published 2018-12-01

Cytotoxic capacity of SIV-specific CD8(+) T cells against primary autologous targets correlates with immune control in SIV-infected rhesus macaques.

by Daniel Mendoza, Stephen A Migueles, Julia E Rood, Bennett Peterson, Sarah Johnson, Nicole Doria-Rose, Douglas Schneider, Eva Rakasz, Matthew T Trivett, Charles M Trubey, Vicky Coalter, Claire W Hallahan, David Watkins, Genoveffa Franchini, Jeffrey D Lifson, Mark Connors
Published 2013-02-01

Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation.

by Ema T Crooks, Samantha L Grimley, Michelle Cully, Keiko Osawa, Gillian Dekkers, Kevin Saunders, Sebastian Rämisch, Sergey Menis, William R Schief, Nicole Doria-Rose, Barton Haynes, Ben Murrell, Evan Mitchel Cale, Amarendra Pegu, John R Mascola, Gestur Vidarsson, James M Binley
Published 2018-05-01

Toll-like receptor 7-adapter complex modulates interferon-α production in HIV-stimulated plasmacytoid dendritic cells.

by Andy A Patamawenu, Nathaniel E Wright, Tulley Shofner, Sean Evans, Maura M Manion, Nicole Doria-Rose, Stephen A Migueles, Daniel Mendoza, Bennett Peterson, Christopher Wilhelm, Julia Rood, Amy Berkley, Nancy A Cogliano, C Jason Liang, Kiki Tesselaar, Frank Miedema, Julian Bess, Jeffrey Lifson, Mark Connors
Published 2019-01-01

Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.

by Sean P O'Brien, Adrienne E Swanstrom, Amarendra Pegu, Sung-Youl Ko, Taina T Immonen, Gregory Q Del Prete, Christine M Fennessey, Jason Gorman, Kathryn E Foulds, Stephen D Schmidt, Nicole Doria-Rose, Carolyn Williamson, Theodora Hatziioannou, Paul D Bieniasz, Hui Li, George M Shaw, John R Mascola, Richard A Koup, Peter D Kwong, Jeffrey D Lifson, Mario Roederer, Brandon F Keele
Published 2019-04-01

Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site.

by Ema T Crooks, Tommy Tong, Bimal Chakrabarti, Kristin Narayan, Ivelin S Georgiev, Sergey Menis, Xiaoxing Huang, Daniel Kulp, Keiko Osawa, Janelle Muranaka, Guillaume Stewart-Jones, Joanne Destefano, Sijy O'Dell, Celia LaBranche, James E Robinson, David C Montefiori, Krisha McKee, Sean X Du, Nicole Doria-Rose, Peter D Kwong, John R Mascola, Ping Zhu, William R Schief, Richard T Wyatt, Robert G Whalen, James M Binley
Published 2015-05-01

Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects

by Madeleine F. Jennewein, Anna J. MacCamy, Nicholas R. Akins, Junli Feng, Leah J. Homad, Nicholas K. Hurlburt, Emilie Seydoux, Yu-Hsin Wan, Andrew B. Stuart, Venkata Viswanadh Edara, Katharine Floyd, Abigail Vanderheiden, John R. Mascola, Nicole Doria-Rose, Lingshu Wang, Eun Sung Yang, Helen Y. Chu, Jonathan L. Torres, Gabriel Ozorowski, Andrew B. Ward, Rachael E. Whaley, Kristen W. Cohen, Marie Pancera, M. Juliana McElrath, Janet A. Englund, Andrés Finzi, Mehul S. Suthar, Andrew T. McGuire, Leonidas Stamatatos
Published 2021-07-01