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Nikolić, M.R
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Nikolić, M.R
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Antipsychotic clozapine binding to alpha-2-macroglobulin protects interacting partners against oxidation and preserves the anti-proteinase activity of the protein
by
Gligorijević, N.
,
Milčić, M.
,
Miljević, Č
,
Nedić, O.
,
Nikolić
,
M.R
,
Šunderić, M.
,
Vasović, T.
Published 2021
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Related Subjects
2,2' azobis 2 methyl propanimidamide
A2M protein, human
Alpha-2-macroglobulin
Antipsychotic Agents
Article
Binding Sites
Clozapine
Humans
Hydrogen Bonding
Hydrophobic and Hydrophilic Interactions
Molecular Docking Simulation
Oxidation-Reduction
Oxidative Stress
Protein Binding
Protein Conformation
Protein-ligand interaction
Structure-Activity Relationship
alpha 2 macroglobulin
alpha-Macroglobulins
association constant
binding affinity
binding site
chemical phenomena
chemistry
clozapine
complex formation
drug protein binding
enzyme activity
free radical
human
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