Mitochondrial oxidative function in NAFLD: Friend or foe?

by Michael Shum, Jennifer Ngo, Orian S. Shirihai, Marc Liesa
Published 2021-08-01

Mitochondrial Heterogeneity in Metabolic Diseases

by Jennifer Ngo, Corey Osto, Frankie Villalobos, Orian S. Shirihai
Published 2021-09-01

ATP Binding and Hydrolysis Properties of ABCB10 and Their Regulation by Glutathione.

by Wei Qiu, Marc Liesa, Elizabeth P Carpenter, Orian S Shirihai
Published 2015-01-01

Utilization of Human Samples for Assessment of Mitochondrial Bioenergetics: Gold Standards, Limitations, and Future Perspectives

by Rebeca Acin-Perez, Cristiane Benincá, Byourak Shabane, Orian S. Shirihai, Linsey Stiles
Published 2021-09-01

BET Bromodomain Proteins Brd2, Brd3 and Brd4 Selectively Regulate Metabolic Pathways in the Pancreatic β-Cell.

by Jude T Deeney, Anna C Belkina, Orian S Shirihai, Barbara E Corkey, Gerald V Denis
Published 2016-01-01

Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics

by Alvaro M. Gonzalez-Ibanez, Alvaro M. Gonzalez-Ibanez, Lina M. Ruiz, Erik Jensen, Cesar A. Echeverria, Valentina Romero, Linsey Stiles, Linsey Stiles, Orian S. Shirihai, Orian S. Shirihai, Alvaro A. Elorza, Alvaro A. Elorza
Published 2020-11-01

Insulin signaling regulates mitochondrial function in pancreatic beta-cells.

by Siming Liu, Terumasa Okada, Anke Assmann, Jamie Soto, Chong Wee Liew, Heiko Bugger, Orian S Shirihai, E Dale Abel, Rohit N Kulkarni
Published 2009-11-01

The ApoA-I mimetic peptide 4F attenuates in vitro replication of SARS-CoV-2, associated apoptosis, oxidative stress and inflammation in epithelial cells

by Theodoros Kelesidis, Madhav Sharma, Anton Petcherski, Cristelle Hugo, Ellen O’Connor, Nan W Hultgren, Eleni Ritou, David S Williams, Orian S Shirihai, Srinivasa T Reddy
Published 2021-01-01

Correction: A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets

by Jakob D. Wikstrom, Samuel B. Sereda, Linsey Stiles, Alvaro Elorza, Emma M. Allister, Andy Neilson, David A. Ferrick, Michael B. Wheeler, Orian S. Shirihai
Published 2013-01-01

Correction: A Novel High-Throughput Assay for Islet Respiration Reveals Uncoupling of Rodent and Human Islets.

by Jakob D. Wikstrom, Samuel B. Sereda, Linsey Stiles, Alvaro Elorza, Emma M. Allister, Andy Neilson, David A. Ferrick, Michael B. Wheeler, Orian S. Shirihai
Published 2013-01-01

A novel high-throughput assay for islet respiration reveals uncoupling of rodent and human islets.

by Jakob D Wikstrom, Samuel B Sereda, Linsey Stiles, Alvaro Elorza, Emma M Allister, Andy Neilson, David A Ferrick, Michael B Wheeler, Orian S Shirihai
Published 2012-01-01

Isolation and functional analysis of peridroplet mitochondria from murine brown adipose tissue

by Jennifer Ngo, Ilan Y. Benador, Alexandra J. Brownstein, Laurent Vergnes, Michaela Veliova, Michael Shum, Rebeca Acín-Pérez, Karen Reue, Orian S. Shirihai, Marc Liesa
Published 2021-03-01

A new target for an old DUB: UCH-L1 regulates mitofusin-2 levels, altering mitochondrial morphology, function and calcium uptake

by Fernanda M. Cerqueira, Sophia von Stockum, Marta Giacomello, Inna Goliand, Pamela Kakimoto, Elena Marchesan, Diego De Stefani, Alicia J. Kowaltowski, Elena Ziviani, Orian S. Shirihai
Published 2020-10-01

NCLX prevents cell death during adrenergic activation of the brown adipose tissue

by Essam A. Assali, Anthony E. Jones, Michaela Veliova, Rebeca Acín-Pérez, Mahmoud Taha, Nathanael Miller, Michaël Shum, Marcus F. Oliveira, Guy Las, Marc Liesa, Israel Sekler, Orian S. Shirihai
Published 2020-07-01

Publisher Correction: IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function

by Chiara Montemurro, Hiroshi Nomoto, Lina Pei, Vishal S. Parekh, Kenny E. Vongbunyong, Suryakiran Vadrevu, Tatyana Gurlo, Alexandra E. Butler, Rohan Subramaniam, Eleni Ritou, Orian S. Shirihai, Leslie S. Satin, Peter C. Butler, Slavica Tudzarova
Published 2019-07-01

IAPP toxicity activates HIF1α/PFKFB3 signaling delaying β-cell loss at the expense of β-cell function

by Chiara Montemurro, Hiroshi Nomoto, Lina Pei, Vishal S. Parekh, Kenny E. Vongbunyong, Suryakiran Vadrevu, Tatyana Gurlo, Alexandra E. Butler, Rohan Subramaniam, Eleni Ritou, Orian S. Shirihai, Leslie S. Satin, Peter C. Butler, Slavica Tudzarova
Published 2019-06-01

Individual islet respirometry reveals functional diversity within the islet population of mice and human donors

by Evan P. Taddeo, Linsey Stiles, Samuel Sereda, Eleni Ritou, Dane M. Wolf, Muhamad Abdullah, Zachary Swanson, Josh Wilhelm, Melena Bellin, Patrick McDonald, Kacey Caradonna, Andrew Neilson, Marc Liesa, Orian S. Shirihai
Published 2018-10-01

Recruitment and remodeling of peridroplet mitochondria in human adipose tissue

by Rebeca Acín-Perez, Anton Petcherski, Michaela Veliova, Ilan Y. Benador, Essam A. Assali, Georgia Colleluori, Saverio Cinti, Alexandra J. Brownstein, Siyouneh Baghdasarian, Masha J. Livhits, Michael W. Yeh, Karthickeyan Chella Krishnan, Laurent Vergnes, Nathan C. Winn, Jaume Padilla, Marc Liesa, Harold S. Sacks, Orian S. Shirihai
Published 2021-10-01

Mitochondrial GTP Links Nutrient Sensing to β Cell Health, Mitochondrial Morphology, and Insulin Secretion Independent of OxPhos

by Sean R. Jesinkey, Anila K. Madiraju, Tiago C. Alves, OrLando H. Yarborough, Rebecca L. Cardone, Xiaojian Zhao, Yassmin Parsaei, Ali R. Nasiri, Gina Butrico, Xinran Liu, Anthony J. Molina, Austin M. Rountree, Adam S. Neal, Dane M. Wolf, John Sterpka, William M. Philbrick, Ian R. Sweet, Orian H. Shirihai, Richard G. Kibbey
Published 2019-07-01

Emergence of a Stage-Dependent Human Liver Disease Signature with Directed Differentiation of Alpha-1 Antitrypsin-Deficient iPS Cells

by Andrew A. Wilson, Lei Ying, Marc Liesa, Charis-Patricia Segeritz, Jason A. Mills, Steven S. Shen, Jyhchang Jean, Geordie C. Lonza, Derek C. Liberti, Alex H. Lang, Jean Nazaire, Adam C. Gower, Franz-Josef Müeller, Pankaj Mehta, Adriana Ordóñez, David A. Lomas, Ludovic Vallier, George J. Murphy, Gustavo Mostoslavsky, Avrum Spira, Orian S. Shirihai, Maria I. Ramirez, Paul Gadue, Darrell N. Kotton
Published 2015-05-01