CpG island structure and trithorax/polycomb chromatin domains in human cells

by Orlando, David A., Guenther, Matthew G., Frampton, Garrett M., Young, Richard A.
Published 2016

Multiple Structural Maintenance of Chromosome Complexes at Transcriptional Regulatory Elements

by Dowen, Jill M, Bilodeau, Steve, Orlando, David A., Hübner, Michael R, Abraham, Brian J., Spector, David L, Young, Richard A, Young, Richard A.
Published 2014

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

by Loven, Jakob, Hoke, Heather Ashley, Lin, Charles Y., Lau, Ashley, Orlando, David A., Vakoc, Christopher R., Bradner, James E., Lee, Tong Ihn, Young, Richard A.
Published 2014

Revisiting Global Gene Expression Analysis

by Loven, Jakob, Orlando, David A., Sigova, Alla A, Lin, Charles Y., Rahl, Peter B, Burge, Christopher B., Levens, David L, Lee, Tong Ihn, Young, Richard A
Published 2015

Master Transcription Factors Determine Cell-Type-Specific Responses to TGF-β Signaling

by Mullen, Alan C., Orlando, David A., Newman, Jamie Jennifer, Loven, Jakob, Kumar, Roshan M., Bilodeau, Steve, Reddy, Jessica, Guenther, Matthew G., DeKoter, Rodney P., Young, Richard A
Published 2014

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

by Whyte, Warren A, Orlando, David A, Hnisz, Denes, Abraham, Brian J, Lin, Charles Y, Kagey, Michael H, Rahl, Peter B, Lee, Tong Ihn, Young, Richard A, Young, Richard A.
Published 2016

Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells

by Almada, Albert Ernesto, Lin, Charles, Sharp, Phillip A., Young, Richard A., Sigova, Alla A., Mullen, Alan C., Molinie, Benoit, Gupta, Sumeet, Orlando, David A., Guenther, Matthew G., Giallourakis, Cosmas C.
Published 2013

Mediator and cohesin connect gene expression and chromatin architecture

by Kagey, Michael H., Newman, Jamie Jennifer, Bilodeau, Steve, Zhan, Ye, Orlando, David A., van Berkum, Nynke L., Ebmeier, Christopher C., Goossens, Jesse, Rahl, Peter B., Levine, Stuart S., Taatjes, Dylan J., Dekker, Job, Young, Richard A.
Published 2012

Global Transcriptional and Translational Repression in Human-Embryonic-Stem-Cell-Derived Rett Syndrome Neurons

by Li, Yun, Wang, Haoyi, Muffat, Julien, Cheng, Albert W, Orlando, David A., Feldman, Danielle A, Bateup, Helen S, Gao, Qing, Hockemeyer, Dirk, Mitalipova, Maisam, Lewis, Caroline A, Sur, Mriganka, Young, Richard A, Jaenisch, Rudolf, Loven, Jakob, Vander Heiden, Matthew G., Feldman, Danielle A., Young, Richard A., Lewis, Caroline, Kwok, Show Ming
Published 2016

The SETDB1 histone methyltransferase is recurrently amplified in and accelerates melanoma

by Ceol, Craig J., Houvras, Yariv, Jane-Valbuena, Judit, Bilodeau, Steve, Orlando, David A., Battisti, Valentine, Fritsch, Lauriane, Lin, William M., Hollmann, Travis J., Ferre, Fabrizio, Bourque, Caitlin, Burke, Christopher J., Turner, Laura, Uong, Audrey, Johnson, Laura A., Beroukhim, Rameen, Mermel, Craig H., Loda, Massimo, Ait-, Garraway, Levi A., Young, Richard A., Zon, Leonard I.
Published 2012