Neuronal Activity and Its Role in Controlling Antioxidant Genes

by Jing Qiu, Owen Dando, James A. Febery, Jill H. Fowler, Siddharthan Chandran, Giles E. Hardingham
Published 2020-03-01

Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes

by Paul S. Baxter, Owen Dando, Katie Emelianova, Xin He, Sean McKay, Giles E. Hardingham, Jing Qiu
Published 2021-03-01

Targeted de-repression of neuronal Nrf2 inhibits α-synuclein accumulation

by Paul S. Baxter, Nóra M. Márkus, Owen Dando, Xin He, Bashayer R. Al-Mubarak, Jing Qiu, Giles E. Hardingham
Published 2021-02-01

Characterisation of CDKL5 Transcript Isoforms in Human and Mouse.

by Ralph D Hector, Owen Dando, Nicoletta Landsberger, Charlotte Kilstrup-Nielsen, Peter C Kind, Mark E S Bailey, Stuart R Cobb
Published 2016-01-01

Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling.

by Nóra M Márkus, Philip Hasel, Jing Qiu, Karen F S Bell, Samuel Heron, Peter C Kind, Owen Dando, T Ian Simpson, Giles E Hardingham
Published 2016-01-01

Generation of pure monocultures of human microglia-like cells from induced pluripotent stem cells

by Poulomi Banerjee, Evdokia Paza, Emma M. Perkins, Owen G. James, Boyd Kenkhuis, Amy F. Lloyd, Karen Burr, David Story, Dilmurat Yusuf, Xin He, Rolf Backofen, Owen Dando, Siddharthan Chandran, Josef Priller
Published 2020-12-01

Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress

by Bashayer R. Al-Mubarak, Karen F.S. Bell, Sudhir Chowdhry, Paul J. Meakin, Paul S. Baxter, Sean McKay, Owen Dando, Michael L.J. Ashford, Irina Gazaryan, John D. Hayes, Giles E. Hardingham
Published 2021-11-01

Altered network properties in C9ORF72 repeat expansion cortical neurons are due to synaptic dysfunction

by Emma M. Perkins, Karen Burr, Poulomi Banerjee, Arpan R. Mehta, Owen Dando, Bhuvaneish T. Selvaraj, Daumante Suminaite, Jyoti Nanda, Christopher M. Henstridge, Thomas H. Gillingwater, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran, Matthew R. Livesey
Published 2021-03-01

Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

by Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C. Todd, Samuel Heron, Nóra M. Márkus, Jamie McQueen, David W. Hampton, Megan Torvell, Sachin S. Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J. A. Wyllie, T. Ian Simpson, Giles E. Hardingham
Published 2017-05-01

Correction: Author Correction: Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism

by Philip Hasel, Owen Dando, Zoeb Jiwaji, Paul Baxter, Alison C. Todd, Samuel Heron, Nóra M. Márkus, Jamie McQueen, David W. Hampton, Megan Torvell, Sachin S. Tiwari, Sean McKay, Abel Eraso-Pichot, Antonio Zorzano, Roser Masgrau, Elena Galea, Siddharthan Chandran, David J. A. Wyllie, T. Ian Simpson, Giles E. Hardingham
Published 2018-02-01

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

by Jing Qiu, Jamie McQueen, Bilada Bilican, Owen Dando, Dario Magnani, Karolina Punovuori, Bhuvaneish T Selvaraj, Matthew Livesey, Ghazal Haghi, Samuel Heron, Karen Burr, Rickie Patani, Rinku Rajan, Olivia Sheppard, Peter C Kind, T Ian Simpson, Victor LJ Tybulewicz, David JA Wyllie, Elizabeth MC Fisher, Sally Lowell, Siddharthan Chandran, Giles E Hardingham
Published 2016-10-01

Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer’s Disease

by Eleanor K. Pickett, Abigail G. Herrmann, Jamie McQueen, Kimberly Abt, Owen Dando, Jane Tulloch, Pooja Jain, Sophie Dunnett, Sadaf Sohrabi, Maria P. Fjeldstad, Will Calkin, Leo Murison, Rosemary J. Jackson, Makis Tzioras, Anna Stevenson, Marie d’Orange, Monique Hooley, Caitlin Davies, Marti Colom-Cadena, Alejandro Anton-Fernandez, Declan King, Iris Oren, Jamie Rose, Chris-Anne McKenzie, Elizabeth Allison, Colin Smith, Oliver Hardt, Christopher M. Henstridge, Giles E. Hardingham, Tara L. Spires-Jones
Published 2019-12-01

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity

by Bhuvaneish T. Selvaraj, Matthew R. Livesey, Chen Zhao, Jenna M. Gregory, Owain T. James, Elaine M. Cleary, Amit K. Chouhan, Angus B. Gane, Emma M. Perkins, Owen Dando, Simon G. Lillico, Youn-Bok Lee, Agnes L. Nishimura, Urjana Poreci, Sai Thankamony, Meryll Pray, Navneet A. Vasistha, Dario Magnani, Shyamanga Borooah, Karen Burr, David Story, Alexander McCampbell, Christopher E. Shaw, Peter C. Kind, Timothy J. Aitman, C. Bruce A. Whitelaw, Ian Wilmut, Colin Smith, Gareth B. Miles, Giles E. Hardingham, David J. A. Wyllie, Siddharthan Chandran
Published 2018-01-01