Anorexigenic and Orexigenic Hormone Modulation of Mammalian Target of Rapamycin Complex 1 Activity and the Regulation of Hypothalamic Agouti-Related Protein mRNA Expression

by Kenneth R. Watterson, Dawn Bestow, Jennifer Gallagher, D. Lee Hamilton, Fiona B. Ashford, Paul J. Meakin, Michael L.J. Ashford
Published 2012-03-01

Calcium Channel CaV2.3 Subunits Regulate Hepatic Glucose Production by Modulating Leptin-Induced Excitation of Arcuate Pro-opiomelanocortin Neurons

by Mark A. Smith, Loukia Katsouri, Samuel Virtue, Agharul I. Choudhury, Antonio Vidal-Puig, Michael L.J. Ashford, Dominic J. Withers
Published 2018-10-01

Mice Lacking beta2-Integrin Function Remain Glucose Tolerant in Spite of Insulin Resistance, Neutrophil Infiltration and Inflammation.

by Paul J Meakin, Vicky L Morrison, Claire C Sneddon, Terhi Savinko, Liisa Uotila, Susan M Jalicy, Jennie L Gabriel, Li Kang, Michael L J Ashford, Susanna C Fagerholm
Published 2015-01-01

Adipocyte integrin-linked kinase plays a key role in the development of diet-induced adipose insulin resistance in male mice

by Aimée R. Bugler-Lamb, Annie Hasib, Xiong Weng, Chandani K. Hennayake, Chenshi Lin, Rory J. McCrimmon, Roland H. Stimson, Michael L.J. Ashford, David H. Wasserman, Li Kang
Published 2021-07-01

The genetic association of the transcription factor NPAT with glycemic response to metformin involves regulation of fuel selection.

by Changwei Chen, Jennifer R Gallagher, Jamie Tarlton, Lidy van Aalten, Susan E Bray, Michael L J Ashford, Rory J McCrimmon, Ewan R Pearson, Alison D McNeilly, Calum Sutherland
Published 2021-01-01

The beta secretase BACE1 regulates the expression of insulin receptor in the liver

by Paul J. Meakin, Anna Mezzapesa, Eva Benabou, Mary E. Haas, Bernadette Bonardo, Michel Grino, Jean-Michel Brunel, Christèle Desbois-Mouthon, Sudha B. Biddinger, Roland Govers, Michael L. J. Ashford, Franck Peiretti
Published 2018-04-01

Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress

by Bashayer R. Al-Mubarak, Karen F.S. Bell, Sudhir Chowdhry, Paul J. Meakin, Paul S. Baxter, Sean McKay, Owen Dando, Michael L.J. Ashford, Irina Gazaryan, John D. Hayes, Giles E. Hardingham
Published 2021-11-01

Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2)

by Ritu S. Sharma, David J. Harrison, Dorothy Kisielewski, Diane M. Cassidy, Alison D. McNeilly, Jennifer R. Gallagher, Shaun V. Walsh, Tadashi Honda, Rory J. McCrimmon, Albena T. Dinkova-Kostova, Michael L.J. Ashford, John F. Dillon, John D. Hayes
Published 2018-01-01