Fluctuating and Geographically Specific Selection Characterize Rapid Evolution of the Human KIR Region

by Danillo G. Augusto, Paul J. Norman, Ravi Dandekar, Jill A. Hollenbach
Published 2019-05-01

High-Resolution Analysis Identifies High Frequency of KIR-A Haplotypes and Inhibitory Interactions of KIR With HLA Class I in Zhejiang Han

by Sudan Tao, Yanmin He, Katherine M. Kichula, Jielin Wang, Ji He, Paul J. Norman, Faming Zhu
Published 2021-04-01

KIR Variation in Iranians Combines High Haplotype and Allotype Diversity With an Abundance of Functional Inhibitory Receptors

by Claudia Alicata, Elham Ashouri, Elham Ashouri, Elham Ashouri, Elham Ashouri, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Wesley M. Marin, Sudan Tao, Sudan Tao, Lorenzo Moretta, Jill A. Hollenbach, John Trowsdale, James A. Traherne, Abbas Ghaderi, Peter Parham, Peter Parham, Paul J. Norman, Paul J. Norman, Paul J. Norman
Published 2020-04-01

Race, Ethnicity and Ancestry in Unrelated Transplant Matching for the National Marrow Donor Program: A Comparison of Multiple Forms of Self-Identification with Genetics.

by Jill A Hollenbach, Aliya Saperstein, Mark Albrecht, Cynthia Vierra-Green, Peter Parham, Paul J Norman, Martin Maiers
Published 2015-01-01

High-Resolution Characterization of KIR Genes in a Large North American Cohort Reveals Novel Details of Structural and Sequence Diversity

by Leonardo M. Amorim, Danillo G. Augusto, Neda Nemat-Gorgani, Gonzalo Montero-Martin, Wesley M. Marin, Hengameh Shams, Ravi Dandekar, Stacy Caillier, Peter Parham, Marcelo A. Fernández-Viña, Jorge R. Oksenberg, Paul J. Norman, Paul J. Norman, Jill A. Hollenbach
Published 2021-05-01

Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles.

by James Robinson, Lisbeth A Guethlein, Nezih Cereb, Soo Young Yang, Paul J Norman, Steven G E Marsh, Peter Parham
Published 2017-06-01

High-throughput Interpretation of Killer-cell Immunoglobulin-like Receptor Short-read Sequencing Data with PING.

by Wesley M Marin, Ravi Dandekar, Danillo G Augusto, Tasneem Yusufali, Bianca Heyn, Jan Hofmann, Vinzenz Lange, Jürgen Sauter, Paul J Norman, Jill A Hollenbach
Published 2021-08-01

Signature Patterns of MHC Diversity in Three Gombe Communities of Wild Chimpanzees Reflect Fitness in Reproduction and Immune Defense against SIVcpz.

by Emily E Wroblewski, Paul J Norman, Lisbeth A Guethlein, Rebecca S Rudicell, Miguel A Ramirez, Yingying Li, Beatrice H Hahn, Anne E Pusey, Peter Parham
Published 2015-05-01

Loss and Gain of Natural Killer Cell Receptor Function in an African Hunter-Gatherer Population.

by Hugo G Hilton, Paul J Norman, Neda Nemat-Gorgani, Ana Goyos, Jill A Hollenbach, Brenna M Henn, Christopher R Gignoux, Lisbeth A Guethlein, Peter Parham
Published 2015-08-01

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

by Chul-Woo Pyo, Lisbeth A Guethlein, Quyen Vu, Ruihan Wang, Laurent Abi-Rached, Paul J Norman, Steven G E Marsh, Jeffrey S Miller, Peter Parham, Daniel E Geraghty
Published 2010-12-01

Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates

by Laura A. Leaton, Laura A. Leaton, Jonathan Shortt, Katherine M. Kichula, Katherine M. Kichula, Sudan Tao, Sudan Tao, Sudan Tao, Neda Nemat-Gorgani, Neda Nemat-Gorgani, Alexander J. Mentzer, Stephen J. Oppenheimer, Zhihui Deng, Jill A. Hollenbach, Christopher R. Gignoux, Lisbeth A. Guethlein, Lisbeth A. Guethlein, Peter Parham, Peter Parham, Mary Carrington, Mary Carrington, Paul J. Norman, Paul J. Norman
Published 2019-01-01

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.

by Paul J Norman, Jill A Hollenbach, Neda Nemat-Gorgani, Lisbeth A Guethlein, Hugo G Hilton, Marcelo J Pando, Kwadwo A Koram, Eleanor M Riley, Laurent Abi-Rached, Peter Parham
Published 2013-10-01

Genetic diversity of CHC22 clathrin impacts its function in glucose metabolism

by Matteo Fumagalli, Stephane M Camus, Yoan Diekmann, Alice Burke, Marine D Camus, Paul J Norman, Agnel Joseph, Laurent Abi-Rached, Andrea Benazzo, Rita Rasteiro, Iain Mathieson, Maya Topf, Peter Parham, Mark G Thomas, Frances M Brodsky
Published 2019-06-01

Natural Killer Cells Offer Differential Protection From Leukemia in Chinese Southern Han

by Zhihui Deng, Jun Zhao, Siqi Cai, Ying Qi, Qiong Yu, Maureen P. Martin, Xiaojiang Gao, Rui Chen, Jiacai Zhuo, Jianxin Zhen, Jianxin Zhen, Mingjie Zhang, Guobin Zhang, Liumei He, Hongyan Zou, Liang Lu, Weigang Zhu, Wenxu Hong, Mary Carrington, Mary Carrington, Paul J. Norman
Published 2019-07-01

Allele-Level KIR Genotyping of More Than a Million Samples: Workflow, Algorithm, and Observations

by Ines Wagner, Daniel Schefzyk, Jens Pruschke, Gerhard Schöfl, Bianca Schöne, Nicole Gruber, Kathrin Lang, Jan Hofmann, Christine Gnahm, Bianca Heyn, Wesley M. Marin, Ravi Dandekar, Jill A. Hollenbach, Johannes Schetelig, Johannes Schetelig, Julia Pingel, Paul J. Norman, Jürgen Sauter, Alexander H. Schmidt, Alexander H. Schmidt, Vinzenz Lange
Published 2018-12-01

Reconstructing the population genetic history of the Caribbean.

by Andrés Moreno-Estrada, Simon Gravel, Fouad Zakharia, Jacob L McCauley, Jake K Byrnes, Christopher R Gignoux, Patricia A Ortiz-Tello, Ricardo J Martínez, Dale J Hedges, Richard W Morris, Celeste Eng, Karla Sandoval, Suehelay Acevedo-Acevedo, Paul J Norman, Zulay Layrisse, Peter Parham, Juan Carlos Martínez-Cruzado, Esteban González Burchard, Michael L Cuccaro, Eden R Martin, Carlos D Bustamante
Published 2013-11-01

Large-Scale Imputation of KIR Copy Number and HLA Alleles in North American and European Psoriasis Case-Control Cohorts Reveals Association of Inhibitory KIR2DL2 With Psoriasis

by Richard Ahn, Richard Ahn, Damjan Vukcevic, Damjan Vukcevic, Damjan Vukcevic, Allan Motyer, Allan Motyer, Joanne Nititham, David McG. Squire, David McG. Squire, Jill A. Hollenbach, Paul J. Norman, Eva Ellinghaus, Rajan P. Nair, Lam C. Tsoi, Lam C. Tsoi, Lam C. Tsoi, Jorge Oksenberg, John Foerster, Wolfgang Lieb, Stephan Weidinger, Andre Franke, James T. Elder, James T. Elder, Eric Jorgenson, Stephen Leslie, Stephen Leslie, Stephen Leslie, Wilson Liao
Published 2021-06-01