Variation in CYP2A6 Activity and Personalized Medicine

by Julie-Anne Tanner, Rachel F. Tyndale
Published 2017-12-01

Pilot Study of CYP2B6 Genetic Variation to Explore the Contribution of Nitrosamine Activation to Lung Carcinogenesis

by Rachel F. Tyndale, Margaret R. Spitz, Christopher I. Amos, Catherine A. Wassenaar, Qiong Dong
Published 2013-04-01

Long-term effectiveness of mailed nicotine replacement therapy: study protocol of a randomized controlled trial 5-year follow-up

by Vladyslav Kushnir, Peter Selby, Laurie Zawertailo, Rachel F. Tyndale, Scott T. Leatherdale, John A. Cunningham
Published 2017-07-01

Variation in trans-3'-hydroxycotinine glucuronidation does not alter the nicotine metabolite ratio or nicotine intake.

by Andy Z X Zhu, Qian Zhou, Lisa Sanderson Cox, Jasjit S Ahluwalia, Neal L Benowitz, Rachel F Tyndale
Published 2013-01-01

C57BL/6 Substrain Differences in Pharmacological Effects after Acute and Repeated Nicotine Administration

by Lois S. Akinola, Bryan Mckiver, Wisam Toma, Andy Z. X. Zhu, Rachel F. Tyndale, Vivek Kumar, M. Imad Damaj
Published 2019-09-01

The CB1R rs2023239 receptor gene variant significantly affects the reinforcing effects of nicotine, but not cue reactivity, in human smokers

by Chidera C. Chukwueke, William J. Kowalczyk, Marie Gendy, Richard Taylor, Rachel F. Tyndale, Bernard Le Foll, Stephen J. Heishman
Published 2021-02-01

The association between self-reported varenicline adherence and varenicline blood levels in a sample of cancer patients receiving treatment for tobacco dependence

by Grace Crawford, Nancy Jao, Annie R. Peng, Frank Leone, Ravi Kalhan, Rachel F. Tyndale, Jessica Weisbrot, Brian Hitsman, Robert Schnoll
Published 2018-12-01

Analyses of nicotine metabolism biomarker genetics stratified by sex in African and European Americans

by Meghan J. Chenoweth, Lisa Sanderson Cox, Nikki L. Nollen, Jasjit S. Ahluwalia, Neal L. Benowitz, Caryn Lerman, Jo Knight, Rachel F. Tyndale
Published 2021-10-01

Personalized dosing of nicotine replacement therapy versus standard dosing for the treatment of individuals with tobacco dependence: study protocol for a randomized placebo-control...

by Laurie Zawertailo, Christian S. Hendershot, Rachel F. Tyndale, Bernard Le Foll, Andriy V. Samokhvalov, Kevin E. Thorpe, Andrew Pipe, Robert D. Reid, Peter Selby
Published 2020-06-01

Sex difference in dopamine D1-D2 receptor complex expression and signaling affects depression- and anxiety-like behaviors

by Ahmed Hasbi, Tuan Nguyen, Haneen Rahal, Joshua D. Manduca, Sharon Miksys, Rachel F. Tyndale, Bertha K. Madras, Melissa L. Perreault, Susan R. George
Published 2020-02-01

Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci

by Richa Gupta, Jenny van Dongen, Yu Fu, Abdel Abdellaoui, Rachel F. Tyndale, Vidya Velagapudi, Dorret I. Boomsma, Tellervo Korhonen, Jaakko Kaprio, Anu Loukola, Miina Ollikainen
Published 2019-01-01

Effects of Menthol on Nicotine Pharmacokinetic, Pharmacology and Dependence in Mice.

by Shakir D Alsharari, Justin R King, Jacob C Nordman, Pretal P Muldoon, Asti Jackson, Andy Z X Zhu, Rachel F Tyndale, Nadine Kabbani, M Imad Damaj
Published 2015-01-01

Developmental hippocampal neuroplasticity in a model of nicotine replacement therapy during pregnancy and breastfeeding.

by Ian Mahar, Rosemary C Bagot, Maria Antonietta Davoli, Sharon Miksys, Rachel F Tyndale, Claire-Dominique Walker, Marissa Maheu, Sheng-Hai Huang, Tak Pan Wong, Naguib Mechawar
Published 2012-01-01

Using a Mobile Laboratory to Study Mental Health, Addictions and Violence: A Research Plan

by Samantha Wells, Andrea Flynn, Kathryn Graham, Jürgen Rehm, John Cairney, Nick Kates, James L. Kennedy, Daniela S.S. Lobo, Michael Chaiton, Peter Menzies, Rachel F. Tyndale, Zulfikarali Verjee
Published 2011-01-01

Lack of Associations of CHRNA5-A3-B4 Genetic Variants with Smoking Cessation Treatment Outcomes in Caucasian Smokers despite Associations with Baseline Smoking.

by Rachel F Tyndale, Andy Z X Zhu, Tony P George, Paul Cinciripini, Larry W Hawk, Robert A Schnoll, Gary E Swan, Neal L Benowitz, Daniel F Heitjan, Caryn Lerman, PGRN-PNAT Research Group
Published 2015-01-01

A Genome-Wide Association Study of a Biomarker of Nicotine Metabolism.

by Anu Loukola, Jadwiga Buchwald, Richa Gupta, Teemu Palviainen, Jenni Hällfors, Emmi Tikkanen, Tellervo Korhonen, Miina Ollikainen, Antti-Pekka Sarin, Samuli Ripatti, Terho Lehtimäki, Olli Raitakari, Veikko Salomaa, Richard J Rose, Rachel F Tyndale, Jaakko Kaprio
Published 2015-01-01

Data on the endogenous conversion of tyrosol into hydroxytyrosol in humans

by Anna Boronat, Julian Mateus, Natalia Soldevila-Domenech, Mercè Guerra, Jose Rodríguez-Morató, Carlota Varon, Daniel Muñoz, Francina Barbosa, Juan Carlos Morales, Andreas Gaedigk, Klaus Langohr, Maria-Isabel Covas, Clara Pérez-Mañá, Montserrat Fitó, Rachel F. Tyndale, Rafael de la Torre
Published 2019-12-01

Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption.

by Andrew W Bergen, Martha Michel, Denise Nishita, Ruth Krasnow, Harold S Javitz, Karen N Conneely, Christina N Lessov-Schlaggar, Hyman Hops, Andy Z X Zhu, James W Baurley, Jennifer B McClure, Sharon M Hall, Timothy B Baker, David V Conti, Neal L Benowitz, Caryn Lerman, Rachel F Tyndale, Gary E Swan, Transdisciplinary Research in Cancer of the Lung Research Team
Published 2015-01-01

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

by Xuemei Ji, Yohan Bossé, Maria Teresa Landi, Jiang Gui, Xiangjun Xiao, David Qian, Philippe Joubert, Maxime Lamontagne, Yafang Li, Ivan Gorlov, Mariella de Biasi, Younghun Han, Olga Gorlova, Rayjean J. Hung, Xifeng Wu, James McKay, Xuchen Zong, Robert Carreras-Torres, David C. Christiani, Neil Caporaso, Mattias Johansson, Geoffrey Liu, Stig E. Bojesen, Loic Le Marchand, Demetrios Albanes, Heike Bickeböller, Melinda C. Aldrich, William S. Bush, Adonina Tardon, Gad Rennert, Chu Chen, M. Dawn Teare, John K. Field, Lambertus A. Kiemeney, Philip Lazarus, Aage Haugen, Stephen Lam, Matthew B. Schabath, Angeline S. Andrew, Hongbing Shen, Yun-Chul Hong, Jian-Min Yuan, Pier A. Bertazzi, Angela C. Pesatori, Yuanqing Ye, Nancy Diao, Li Su, Ruyang Zhang, Yonathan Brhane, Natasha Leighl, Jakob S. Johansen, Anders Mellemgaard, Walid Saliba, Christopher Haiman, Lynne Wilkens, Ana Fernandez-Somoano, Guillermo Fernandez-Tardon, Erik H. F. M. van der Heijden, Jin Hee Kim, Juncheng Dai, Zhibin Hu, Michael P. A. Davies, Michael W. Marcus, Hans Brunnström, Jonas Manjer, Olle Melander, David C. Muller, Kim Overvad, Antonia Trichopoulou, Rosario Tumino, Jennifer Doherty, Gary E. Goodman, Angela Cox, Fiona Taylor, Penella Woll, Irene Brüske, Judith Manz, Thomas Muley, Angela Risch, Albert Rosenberger, Kjell Grankvist, Mikael Johansson, Frances Shepherd, Ming-Sound Tsao, Susanne M. Arnold, Eric B. Haura, Ciprian Bolca, Ivana Holcatova, Vladimir Janout, Milica Kontic, Jolanta Lissowska, Anush Mukeria, Simona Ognjanovic, Tadeusz M. Orlowski, Ghislaine Scelo, Beata Swiatkowska, David Zaridze, Per Bakke, Vidar Skaug, Shanbeh Zienolddiny, Eric J. Duell, Lesley M. Butler, Woon-Puay Koh, Yu-Tang Gao, Richard Houlston, John McLaughlin, Victoria Stevens, David C. Nickle, Ma’en Obeidat, Wim Timens, Bin Zhu, Lei Song, María Soler Artigas, Martin D. Tobin, Louise V. Wain, Fangyi Gu, Jinyoung Byun, Ahsan Kamal, Dakai Zhu, Rachel F. Tyndale, Wei-Qi Wei, Stephen Chanock, Paul Brennan, Christopher I. Amos
Published 2018-08-01