The Search for New Anticonvulsants in a Group of (2,5-Dioxopyrrolidin-1-yl)(phenyl)Acetamides with Hybrid Structure—Synthesis and In Vivo/In Vitro Studies

by Michał Abram, Marcin Jakubiec, Anna Rapacz, Szczepan Mogilski, Gniewomir Latacz, Rafał M. Kamiński, Krzysztof Kamiński
Published 2020-11-01

Inhibiting Epileptiform Activity in Cognitive Disorders: Possibilities for a Novel Therapeutic Approach

by Andras Attila Horvath, Andras Attila Horvath, Emoke Anna Csernus, Sara Lality, Rafal M. Kaminski, Anita Kamondi, Anita Kamondi
Published 2020-10-01

Electrical, molecular and behavioral effects of interictal spiking in the rat

by Daniel T. Barkmeier, Danielle Senador, Karine Leclercq, Darshan Pai, Jing Hua, Nash N. Boutros, Rafal M. Kaminski, Jeffrey A. Loeb
Published 2012-07-01

Radiprodil, a NR2B negative allosteric modulator, from bench to bedside in infantile spasm syndrome

by Stéphane Auvin, Blandine Dozières‐Puyravel, Andreja Avbersek, David Sciberras, Jo Collier, Karine Leclercq, Pavel Mares, Rafal M. Kaminski, Pierandrea Muglia
Published 2020-03-01

Inhibition of glutamate decarboxylase (GAD) by ethyl ketopentenoate (EKP) induces treatment-resistant epileptic seizures in zebrafish

by Yifan Zhang, Michiel Vanmeert, Aleksandra Siekierska, Annelii Ny, Jubi John, Geert Callewaert, Eveline Lescrinier, Wim Dehaen, Peter A. M. de Witte, Rafal M. Kaminski
Published 2017-08-01

A systems-level framework for drug discovery identifies Csf1R as an anti-epileptic drug target

by Prashant K. Srivastava, Jonathan van Eyll, Patrice Godard, Manuela Mazzuferi, Andree Delahaye-Duriez, Juliette Van Steenwinckel, Pierre Gressens, Benedicte Danis, Catherine Vandenplas, Patrik Foerch, Karine Leclercq, Georges Mairet-Coello, Alvaro Cardenas, Frederic Vanclef, Liisi Laaniste, Isabelle Niespodziany, James Keaney, Julien Gasser, Gaelle Gillet, Kirill Shkura, Seon-Ah Chong, Jacques Behmoaras, Irena Kadiu, Enrico Petretto, Rafal M. Kaminski, Michael R. Johnson
Published 2018-09-01