Imidazoles as Potential Anticancer Agents: An Update on Recent Studies

by Pankaj Sharma, Chris LaRosa, Janet Antwi, Rajgopal Govindarajan, Karl A. Werbovetz
Published 2021-07-01

Differential processing of let-7a precursors influences RRM2 expression and chemosensitivity in pancreatic cancer: role of LIN-28 and SET oncoprotein.

by Yangzom Doma Bhutia, Sau Wai Hung, Madeline Krentz, Dimal Patel, Dylan Lovin, Radhika Manoharan, J Michael Thomson, Rajgopal Govindarajan
Published 2013-01-01

Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies.

by Sau Wai Hung, Hardik Mody, Sean Marrache, Yangzom D Bhutia, Franklin Davis, Jong Hyun Cho, Jason Zastre, Shanta Dhar, Chung K Chu, Rajgopal Govindarajan
Published 2013-01-01

Facilitative lysosomal transport of bile acids alleviates ER stress in mouse hematopoietic precursors

by Avinash K. Persaud, Sreenath Nair, Md Fazlur Rahman, Radhika Raj, Brenna Weadick, Debasis Nayak, Craig McElroy, Muruganandan Shanmugam, Sue Knoblaugh, Xiaolin Cheng, Rajgopal Govindarajan
Published 2021-02-01

Transcriptional suppression, DNA methylation, and histone deacetylation of the regulator of G-protein signaling 10 (RGS10) gene in ovarian cancer cells.

by Mourad W Ali, Ercan Cacan, Yuying Liu, Jennifer Young Pierce, William T Creasman, Mandi M Murph, Rajgopal Govindarajan, Scott T Eblen, Susanna F Greer, Shelley B Hooks
Published 2013-01-01

Adult stem cell deficits drive Slc29a3 disorders in mice

by Sreenath Nair, Anne M. Strohecker, Avinash K. Persaud, Bhawana Bissa, Shanmugam Muruganandan, Craig McElroy, Rakesh Pathak, Michelle Williams, Radhika Raj, Amal Kaddoumi, Alex Sparreboom, Aaron M. Beedle, Rajgopal Govindarajan
Published 2019-07-01

A mild form of SLC29A3 disorder: a frameshift deletion leads to the paradoxical translation of an otherwise noncoding mRNA splice variant.

by Alexandre Bolze, Avinash Abhyankar, Audrey V Grant, Bhavi Patel, Ruchi Yadav, Minji Byun, Daniel Caillez, Jean-Francois Emile, Marçal Pastor-Anglada, Laurent Abel, Anne Puel, Rajgopal Govindarajan, Loic de Pontual, Jean-Laurent Casanova
Published 2012-01-01

A kinome-wide screen identifies a CDKL5-SOX9 regulatory axis in epithelial cell death and kidney injury

by Ji Young Kim, Yuntao Bai, Laura A. Jayne, Ralph D. Hector, Avinash K. Persaud, Su Sien Ong, Shreshtha Rojesh, Radhika Raj, Mei Ji He Ho Feng, Sangwoon Chung, Rachel E. Cianciolo, John W. Christman, Moray J. Campbell, David S. Gardner, Sharyn D. Baker, Alex Sparreboom, Rajgopal Govindarajan, Harpreet Singh, Taosheng Chen, Ming Poi, Katalin Susztak, Stuart R. Cobb, Navjot Singh Pabla
Published 2020-04-01