Ensemble cryoEM elucidates the mechanism of insulin capture and degradation by human insulin degrading enzyme

by Zhening Zhang, Wenguang G Liang, Lucas J Bailey, Yong Zi Tan, Hui Wei, Andrew Wang, Mara Farcasanu, Virgil A Woods, Lauren A McCord, David Lee, Weifeng Shang, Rebecca Deprez-Poulain, Benoit Deprez, David R Liu, Akiko Koide, Shohei Koide, Anthony A Kossiakoff, Sheng Li, Bridget Carragher, Clinton S Potter, Wei-Jen Tang
Published 2018-03-01

ADAM30 Downregulates APP-Linked Defects Through Cathepsin D Activation in Alzheimer's Disease

by Florent Letronne, Geoffroy Laumet, Anne-Marie Ayral, Julien Chapuis, Florie Demiautte, Mathias Laga, Michel E. Vandenberghe, Nicolas Malmanche, Florence Leroux, Fanny Eysert, Yoann Sottejeau, Linda Chami, Amandine Flaig, Charlotte Bauer, Pierre Dourlen, Marie Lesaffre, Charlotte Delay, Ludovic Huot, Julie Dumont, Elisabeth Werkmeister, Franck Lafont, Tiago Mendes, Franck Hansmannel, Bart Dermaut, Benoit Deprez, Anne-Sophie Hérard, Marc Dhenain, Nicolas Souedet, Florence Pasquier, David Tulasne, Claudine Berr, Jean-Jacques Hauw, Yves Lemoine, Philippe Amouyel, David Mann, Rebecca Déprez, Frédéric Checler, David Hot, Thierry Delzescaux, Kris Gevaert, Jean-Charles Lambert
Published 2016-07-01