Microparticles engineered to highly express peroxisome proliferator-activated receptor-γ decreased inflammatory mediator production and increased adhesion of recipient monocytes.

by Julie Sahler, Collynn F Woeller, Richard P Phipps
Published 2014-01-01

Platelet transfusion—the new immunology of an old therapy

by Moritz eStolla, Majed A Refaai, Joanna M. Heal, Sherry L. Spinelli, Olivier eGARRAUD, Richard P. Phipps, Richard P. Phipps, Neil eBlumberg
Published 2015-02-01

Breaking the mold: transcription factors in the anucleate platelet and platelet-derived microparticles

by Katie L Lannan, Julie eSahler, Julie eSahler, Nina eKim, Sherry L Spinelli, Sanjay B Maggirwar, Olivier eGARRAUD, Fabrice eCOGNASSE, Fabrice eCOGNASSE, Neil eBlumberg, Richard P Phipps, Richard P Phipps, Richard P Phipps
Published 2015-02-01

Proton pump inhibitors attenuate myofibroblast formation associated with thyroid eye disease through the aryl hydrocarbon receptor.

by Christine L Hammond, Elisa Roztocil, Richard P Phipps, Steven E Feldon, Collynn F Woeller
Published 2019-01-01

PPARγ and the Innate Immune System Mediate the Resolution of Inflammation

by Amanda Croasdell, Parker F. Duffney, Nina Kim, Shannon H. Lacy, Patricia J. Sime, Richard P. Phipps
Published 2015-01-01

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases

by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime
Published 2012-01-01

The Role of PPARs in Lung Fibrosis

by Heather F. Lakatos, Thomas H. Thatcher, R. Matthew Kottmann, Tatiana M. Garcia, Richard P. Phipps, Patricia J. Sime
Published 2007-01-01

PPAR-γ ligands repress TGFβ-induced myofibroblast differentiation by targeting the PI3K/Akt pathway: implications for therapy of fibrosis.

by Ajit A Kulkarni, Thomas H Thatcher, Keith C Olsen, Sanjay B Maggirwar, Richard P Phipps, Patricia J Sime
Published 2011-01-01

Cigarette smoke increases susceptibility to infection in lung epithelial cells by upregulating caveolin-dependent endocytosis.

by Parker F Duffney, A Karim Embong, Connor C McGuire, Thomas H Thatcher, Richard P Phipps, Patricia J Sime
Published 2020-01-01

Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol.

by Jennifer L Judge, David J Nagel, Kristina M Owens, Ashley Rackow, Richard P Phipps, Patricia J Sime, R M Kottmann
Published 2018-01-01

Discovery of Novel Small Molecules that Block Myofibroblast Formation: Implications for Capsular Contracture Treatment

by Rachel H. Park, BA, Stephen J. Pollock, BSc, Richard P. Phipps, PhD, Howard N. Langstein, MD, Collynn F. Woeller, PhD
Published 2019-09-01

Normal Human Lung Epithelial Cells Inhibit Transforming Growth Factor-β Induced Myofibroblast Differentiation via Prostaglandin E2.

by Amali P Epa, Thomas H Thatcher, Stephen J Pollock, Lindsay A Wahl, Elizabeth Lyda, R M Kottmann, Richard P Phipps, Patricia J Sime
Published 2015-01-01

Topical rosiglitazone is an effective anti-scarring agent in the cornea.

by Krystel R Huxlin, Holly B Hindman, Kye-Im Jeon, Jens Bühren, Scott MacRae, Margaret DeMagistris, David Ciufo, Patricia J Sime, Richard P Phipps
Published 2013-01-01

Role of Peroxisome Proliferator-Activated Receptor Gamma and Its Ligands in the Treatment of Hematological Malignancies

by Richard P. Phipps, <?layout cmd="newline"?> Patricia J. Sime, Steven H. Bernstein, Tatiana M. Garcia-Bates, Geniece M. Lehmann, Patricia J. Simpson-Haidaris
Published 2008-01-01

The triterpenoid CDDO-Me inhibits bleomycin-induced lung inflammation and fibrosis.

by Ajit A Kulkarni, Thomas H Thatcher, Hsi-Min Hsiao, Keith C Olsen, Robert Matthew Kottmann, Jason Morrissette, Terry W Wright, Richard P Phipps, Patricia J Sime
Published 2013-01-01

Electrophilic PPARγ Ligands Attenuate IL-1β and Silica-Induced Inflammatory Mediator Production in Human Lung Fibroblasts via a PPARγ-Independent Mechanism

by Christopher M. Hogan, Thomas H. Thatcher, Ramil E. Sapinoro, Michael N. Gurell, Heather E. Ferguson, Stephen J. Pollock, Carolyn Jones, Richard P. Phipps, Patricia J. Sime
Published 2011-01-01

The polyether ionophore salinomycin targets multiple cellular pathways to block proliferative vitreoretinopathy pathology.

by Alison M Heffer, Jacob Proaño, Elisa Roztocil, Richard P Phipps, Steven E Feldon, Krystel R Huxlin, Patricia J Sime, Richard T Libby, Collynn F Woeller, Ajay E Kuriyan
Published 2019-01-01

A novel anti-inflammatory and pro-resolving role for resolvin D1 in acute cigarette smoke-induced lung inflammation.

by Hsi-Min Hsiao, Ramil E Sapinoro, Thomas H Thatcher, Amanda Croasdell, Elizabeth P Levy, Robert A Fulton, Keith C Olsen, Stephen J Pollock, Charles N Serhan, Richard P Phipps, Patricia J Sime
Published 2013-01-01