If looks could kill: Fungal macroscopic morphology and virulence.

by Caitlin H Kowalski, Robert A Cramer
Published 2020-06-01

Coordination of hypoxia adaptation and iron homeostasis in pathogenic fungi

by Dawoon eChung, Hubertus eHaas, Robert A Cramer
Published 2012-11-01

Platelets are critical for survival and tissue integrity during murine pulmonary Aspergillus fumigatus infection.

by Benjamin Y Tischler, Nicholas L Tosini, Robert A Cramer, Tobias M Hohl
Published 2020-05-01

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus

by Arsa Thammahong, Sourabh Dhingra, Katherine M. Bultman, Joshua D. Kerkaert, Robert A. Cramer
Published 2019-05-01

Aspergillus fumigatus Photobiology Illuminates the Marked Heterogeneity between Isolates

by Kevin K. Fuller, Robert A. Cramer, Michael E. Zegans, Jay C. Dunlap, Jennifer J. Loros
Published 2016-09-01

Erratum for Dhingra et al., “RbdB, a Rhomboid Protease Critical for SREBP Activation and Virulence in Aspergillus fumigatus”

by Sourabh Dhingra, Caitlin H. Kowalski, Arsa Thammahong, Sarah R. Beattie, Katherine M. Bultman, Robert A. Cramer
Published 2019-09-01

Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus.

by Patrícia de Sousa Lima, Dawoon Chung, Alexandre Melo Bailão, Robert A Cramer, Célia Maria de Almeida Soares
Published 2015-12-01

Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity

by Arsa Thammahong, Alayna K. Caffrey-Card, Sourabh Dhingra, Joshua J. Obar, Robert A. Cramer, Tamara L. Doering
Published 2017-04-01

In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis.

by Nora Grahl, Srisombat Puttikamonkul, Jeffrey M Macdonald, Michael P Gamcsik, Lisa Y Ngo, Tobias M Hohl, Robert A Cramer
Published 2011-07-01

RbdB, a Rhomboid Protease Critical for SREBP Activation and Virulence in Aspergillus fumigatus

by Sourabh Dhingra, Caitlin H. Kowlaski, Arsa Thammahong, Sarah R. Beattie, Katherine M. Bultman, Robert A. Cramer, Yong-Sun Bahn
Published 2016-03-01

Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection.

by Kelly M Shepardson, Anupam Jhingran, Alayna Caffrey, Joshua J Obar, Benjamin T Suratt, Brent L Berwin, Tobias M Hohl, Robert A Cramer
Published 2014-09-01

TmpL, a transmembrane protein required for intracellular redox homeostasis and virulence in a plant and an animal fungal pathogen.

by Kwang-Hyung Kim, Sven D Willger, Sang-Wook Park, Srisombat Puttikamonkul, Nora Grahl, Yangrae Cho, Biswarup Mukhopadhyay, Robert A Cramer, Christopher B Lawrence
Published 2009-11-01

Transcriptional regulation of chemical diversity in Aspergillus fumigatus by LaeA.

by Robyn M Perrin, Natalie D Fedorova, Jin Woo Bok, Robert A Cramer, Jennifer R Wortman, H Stanley Kim, William C Nierman, Nancy P Keller
Published 2007-04-01

SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus.

by Michael Blatzer, Bridget M Barker, Sven D Willger, Nicola Beckmann, Sara J Blosser, Elizabeth J Cornish, Aurelien Mazurie, Nora Grahl, Hubertus Haas, Robert A Cramer
Published 2011-12-01

Heterogeneity among Isolates Reveals that Fitness in Low Oxygen Correlates with Aspergillus fumigatus Virulence

by Caitlin H. Kowalski, Sarah R. Beattie, Kevin K. Fuller, Elizabeth A. McGurk, Yi-Wei Tang, Tobias M. Hohl, Joshua J. Obar, Robert A. Cramer
Published 2016-09-01

Reducing Aspergillus fumigatus Virulence through Targeted Dysregulation of the Conidiation Pathway

by James I. P. Stewart, Vinicius M. Fava, Joshua D. Kerkaert, Adithya S. Subramanian, Fabrice N. Gravelat, Melanie Lehoux, P. Lynne Howell, Robert A. Cramer, Donald C. Sheppard
Published 2020-02-01

A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus.

by Sven D Willger, Srisombat Puttikamonkul, Kwang-Hyung Kim, James B Burritt, Nora Grahl, Laurel J Metzler, Robert Barbuch, Martin Bard, Christopher B Lawrence, Robert A Cramer
Published 2008-11-01

Modulation of Immune Signaling and Metabolism Highlights Host and Fungal Transcriptional Responses in Mouse Models of Invasive Pulmonary Aspergillosis

by Shiv D. Kale, Tariq Ayubi, Dawoon Chung, Nuria Tubau-Juni, Andrew Leber, Ha X. Dang, Saikumar Karyala, Raquel Hontecillas, Christopher B. Lawrence, Robert A. Cramer, Josep Bassaganya-Riera
Published 2017-12-01

Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis

by Alayna K. Caffrey-Carr, Alayna K. Caffrey-Carr, Kimberly M. Hilmer, Caitlin H. Kowalski, Kelly M. Shepardson, Kelly M. Shepardson, Rachel M. Temple, Robert A. Cramer, Joshua J. Obar
Published 2018-01-01

Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus

by Leandro José de Assis, Adriana Manfiolli, Eliciane Mattos, João H. T. Marilhano Fabri, Iran Malavazi, Ilse D. Jacobsen, Matthias Brock, Robert A. Cramer, Arsa Thammahong, Daisuke Hagiwara, Laure Nicolas Annick Ries, Gustavo Henrique Goldman
Published 2018-12-01