Autoimmune Disease in Women: Endocrine Transition and Risk Across the Lifespan

by Maunil K. Desai, Roberta Diaz Brinton, Roberta Diaz Brinton
Published 2019-04-01

Transitions in metabolic and immune systems from pre-menopause to post-menopause: implications for age-associated neurodegenerative diseases [version 1; peer review: 2 approved]

by Yiwei Wang, Aarti Mishra, Roberta Diaz Brinton
Published 2020-01-01

Frontiers in therapeutic development of allopregnanolone for Alzheimer's disease and other neurological disorders

by Ronald W. Irwin, Christine M. Solinsky, Roberta Diaz Brinton
Published 2014-07-01

2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease.

by Jia Yao, Shuhua Chen, Zisu Mao, Enrique Cadenas, Roberta Diaz Brinton
Published 2011-01-01

Early decline in glucose transport and metabolism precedes shift to ketogenic system in female aging and Alzheimer's mouse brain: implication for bioenergetic intervention.

by Fan Ding, Jia Yao, Jamaica R Rettberg, Shuhua Chen, Roberta Diaz Brinton
Published 2013-01-01

Data-driven identification of endophenotypes of Alzheimer’s disease progression: implications for clinical trials and therapeutic interventions

by Nophar Geifman, Richard E. Kennedy, Lon S. Schneider, Iain Buchan, Roberta Diaz Brinton
Published 2018-01-01

Neuroregenerative mechanisms of allopregnanolone in Alzheimer's disease

by Ronald W. Irwin, Jun Ming Wang, Shuhua eChen, Roberta Diaz Brinton
Published 2012-01-01

Sex and Gender Driven Modifiers of Alzheimer’s: The Role for Estrogenic Control Across Age, Race, Medical, and Lifestyle Risks

by Aneela Rahman, Hande Jackson, Hollie Hristov, Richard S. Isaacson, Nabeel Saif, Teena Shetty, Orli Etingin, Claire Henchcliffe, Roberta Diaz Brinton, Roberta Diaz Brinton, Lisa Mosconi, Lisa Mosconi, Lisa Mosconi
Published 2019-11-01

Ovariectomy induces a shift in fuel availability and metabolism in the hippocampus of the female transgenic model of familial Alzheimer's.

by Fan Ding, Jia Yao, Liqin Zhao, Zisu Mao, Shuhua Chen, Roberta Diaz Brinton
Published 2013-01-01

Association of combination statin and antihypertensive therapy with reduced Alzheimer's disease and related dementia risk.

by Douglas Barthold, Geoffrey Joyce, Roberta Diaz Brinton, Whitney Wharton, Patrick Gavin Kehoe, Julie Zissimopoulos
Published 2020-01-01

Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease.

by Shuhua Chen, Jun Ming Wang, Ronald W Irwin, Jia Yao, Lifei Liu, Roberta Diaz Brinton
Published 2011-01-01

White Matter Lipids as a Ketogenic Fuel Supply in Aging Female Brain: Implications for Alzheimer's Disease

by Lauren P. Klosinski, Jia Yao, Fei Yin, Alfred N. Fonteh, Michael G. Harrington, Trace A. Christensen, Eugenia Trushina, Roberta Diaz Brinton
Published 2015-12-01

Allopregnanolone preclinical acute pharmacokinetic and pharmacodynamic studies to predict tolerability and efficacy for Alzheimer's disease.

by Ronald W Irwin, Christine M Solinsky, Carlos M Loya, Francesco G Salituro, Kathleen E Rodgers, Gerhard Bauer, Michael A Rogawski, Roberta Diaz Brinton
Published 2015-01-01

Increased Alzheimer's risk during the menopause transition: A 3-year longitudinal brain imaging study.

by Lisa Mosconi, Aneela Rahman, Ivan Diaz, Xian Wu, Olivia Scheyer, Hollie Webb Hristov, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Roberta Diaz Brinton
Published 2018-01-01

A dominant negative ERβ splice variant determines the effectiveness of early or late estrogen therapy after ovariectomy in rats.

by Jun Ming Wang, Xu Hou, Samuel Adeosun, Rosanne Hill, Sherry Henry, Ian Paul, Ronald W Irwin, Xiao-Ming Ou, Steven Bigler, Craig Stockmeier, Roberta Diaz Brinton, Elise Gomez-Sanchez
Published 2012-01-01

Correction: Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.

by Lisa Mosconi, Valentina Berti, Crystal Quinn, Pauline McHugh, Gabriella Petrongolo, Ricardo S Osorio, Christopher Connaughty, Alberto Pupi, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Russell H Swerdlow, Roberta Diaz Brinton
Published 2018-01-01

Perimenopause and emergence of an Alzheimer's bioenergetic phenotype in brain and periphery.

by Lisa Mosconi, Valentina Berti, Crystal Quinn, Pauline McHugh, Gabriella Petrongolo, Ricardo S Osorio, Christopher Connaughty, Alberto Pupi, Shankar Vallabhajosula, Richard S Isaacson, Mony J de Leon, Russell H Swerdlow, Roberta Diaz Brinton
Published 2017-01-01

Menopause impacts human brain structure, connectivity, energy metabolism, and amyloid-beta deposition

by Lisa Mosconi, Valentina Berti, Jonathan Dyke, Eva Schelbaum, Steven Jett, Lacey Loughlin, Grace Jang, Aneela Rahman, Hollie Hristov, Silky Pahlajani, Randolph Andrews, Dawn Matthews, Orli Etingin, Christine Ganzer, Mony de Leon, Richard Isaacson, Roberta Diaz Brinton
Published 2021-06-01

Allopregnanolone reinstates tyrosine hydroxylase immunoreactive neurons and motor performance in an MPTP-lesioned mouse model of Parkinson's disease.

by Samuel O Adeosun, Xu Hou, Yun Jiao, Baoying Zheng, Sherry Henry, Rosanne Hill, Zhi He, Amar Pani, Patrick Kyle, Xiaoming Ou, Thomas Mosley, Jerry M Farley, Craig Stockmeier, Ian Paul, Steven Bigler, Roberta Diaz Brinton, Richard Smeyne, Jun Ming Wang
Published 2012-01-01