PLP-Dependent Enzymes

by Alessandro Paiardini, Roberto Contestabile, Ashley M. Buckle, Barbara Cellini
Published 2014-01-01

Editorial: PLP-Dependent Enzymes: Extraordinary Versatile Catalysts and Ideal Biotechnological Tools for the Production of Unnatural Amino Acids and Related Compounds

by Martino L. Di Salvo, Kateryna Fesko, Robert S. Phillips, Roberto Contestabile
Published 2020-02-01

The multifaceted role of vitamin B6 in cancer: Drosophila as a model system to investigate DNA damage

by Roberto Contestabile, Martino Luigi di Salvo, Victoria Bunik, Angela Tramonti, Fiammetta Vernì
Published 2020-03-01

Asymmetry of the Active Site Loop Conformation between Subunits of Glutamate-1-semialdehyde Aminomutase in Solution

by Barbara Campanini, Stefano Bettati, Martino Luigi di Salvo, Andrea Mozzarelli, Roberto Contestabile
Published 2013-01-01

Coupling Bioorthogonal Chemistries with Artificial Metabolism: Intracellular Biosynthesis of Azidohomoalanine and Its Incorporation into Recombinant Proteins

by Ying Ma, Hernán Biava, Roberto Contestabile, Nediljko Budisa, Martino Luigi di Salvo
Published 2014-01-01

A Bioinformatics Analysis Reveals a Group of MocR Bacterial Transcriptional Regulators Linked to a Family of Genes Coding for Membrane Proteins

by Teresa Milano, Sebastiana Angelaccio, Angela Tramonti, Martino Luigi Di Salvo, Roberto Contestabile, Stefano Pascarella
Published 2016-01-01

Data from computational analysis of the peptide linkers in the MocR bacterial transcriptional regulators

by Sebastiana Angelaccio, Teresa Milano, Angela Tramonti, Martino Luigi Di Salvo, Roberto Contestabile, Stefano Pascarella
Published 2016-12-01

A Novel, Easy Assay Method for Human Cysteine Sulfinic Acid Decarboxylase

by Angela Tramonti, Roberto Contestabile, Rita Florio, Caterina Nardella, Anna Barile, Martino L. Di Salvo
Published 2021-05-01

Structure-Based Mechanism for Early PLP-Mediated Steps of Rabbit Cytosolic Serine Hydroxymethyltransferase Reaction

by Martino L. Di Salvo, J. Neel Scarsdale, Galina Kazanina, Roberto Contestabile, Verne Schirch, H. Tonie Wright
Published 2013-01-01

Isolation of a Complex Formed Between Acinetobacter baumannii HemA and HemL, Key Enzymes of Tetrapyrroles Biosynthesis

by Caterina Nardella, Dalila Boi, Martino L. di Salvo, Anna Barile, Jörg Stetefeld, Angela Tramonti, Angela Tramonti, Roberto Contestabile
Published 2019-02-01

Functional Inactivation of <i>Drosophila</i> <i>GCK</i> Orthologs Causes Genomic Instability and Oxidative Stress in a Fly Model of MODY-2

by Elisa Mascolo, Francesco Liguori, Lorenzo Stufera Mecarelli, Noemi Amoroso, Chiara Merigliano, Susanna Amadio, Cinzia Volonté, Roberto Contestabile, Angela Tramonti, Fiammetta Vernì
Published 2021-01-01

Biochemical data from the characterization of a new pathogenic mutation of human pyridoxine-5'-phosphate oxidase (PNPO)

by Martino L. di Salvo, Mario Mastrangelo, Isabel Nogués, Manuela Tolve, Alessandro Paiardini, Carla Carducci, Davide Mei, Martino Montomoli, Angela Tramonti, Renzo Guerrini, Roberto Contestabile, Vincenzo Leuzzi
Published 2017-12-01

Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.

by Amit K Gandhi, Jigar V Desai, Mohini S Ghatge, Martino L di Salvo, Stefano Di Biase, Richmond Danso-Danquah, Faik N Musayev, Roberto Contestabile, Verne Schirch, Martin K Safo
Published 2012-01-01

The expression of four pyridoxal kinase (PDXK) human variants in Drosophila impacts on genome integrity

by Elisa Mascolo, Anna Barile, Lorenzo Stufera Mecarelli, Noemi Amoroso, Chiara Merigliano, Arianna Massimi, Isabella Saggio, Torben Hansen, Angela Tramonti, Martino Luigi Di Salvo, Fabrizio Barbetti, Roberto Contestabile, Fiammetta Vernì
Published 2019-10-01

Pyridoxal 5'-phosphate is a slow tight binding inhibitor of E. coli pyridoxal kinase.

by Mohini S Ghatge, Roberto Contestabile, Martino L di Salvo, Jigar V Desai, Amit K Gandhi, Christina M Camara, Rita Florio, Isabel N González, Alessia Parroni, Verne Schirch, Martin K Safo
Published 2012-01-01

Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2

by Angela Tramonti, Elisabet Cuyàs, José Antonio Encinar, Matthias Pietzke, Alessio Paone, Sara Verdura, Aina Arbusà, Begoña Martin-Castillo, Giorgio Giardina, Jorge Joven, Alexei Vazquez, Roberto Contestabile, Francesca Cutruzzolà, Javier A. Menendez
Published 2021-08-01