C-di-GMP hydrolysis by Pseudomonas aeruginosa HD-GYP phosphodiesterases: analysis of the reaction mechanism and novel roles for pGpG.

by Valentina Stelitano, Giorgio Giardina, Alessandro Paiardini, Nicoletta Castiglione, Francesca Cutruzzolà, Serena Rinaldo
Published 2013-01-01

Investigating the allosteric regulation of YfiN from Pseudomonas aeruginosa: clues from the structure of the catalytic domain.

by Giorgio Giardina, Alessandro Paiardini, Silvia Fernicola, Stefano Franceschini, Serena Rinaldo, Valentina Stelitano, Francesca Cutruzzolà
Published 2013-01-01

Modelling of SHMT1 riboregulation predicts dynamic changes of serine and glycine levels across cellular compartments

by Michele Monti, Giulia Guiducci, Alessio Paone, Serena Rinaldo, Giorgio Giardina, Francesca Romana Liberati, Francesca Cutruzzolá, Gian Gaetano Tartaglia
Published 2021-01-01

The Emerging Role of Amino Acids of the Brain Microenvironment in the Process of Metastasis Formation

by Francesca Cutruzzolà, Amani Bouzidi, Francesca Romana Liberati, Sharon Spizzichino, Giovanna Boumis, Alberto Macone, Serena Rinaldo, Giorgio Giardina, Alessio Paone
Published 2021-06-01

Fractalkine Modulates Microglia Metabolism in Brain Ischemia

by Clotilde Lauro, Giuseppina Chece, Lucia Monaco, Fabrizio Antonangeli, Giovanna Peruzzi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Cristina Limatola, Cristina Limatola
Published 2019-09-01

Studying GGDEF Domain in the Act: Minimize Conformational Frustration to Prevent Artefacts

by Federico Mantoni, Chiara Scribani Rossi, Alessandro Paiardini, Adele Di Matteo, Loredana Cappellacci, Riccardo Petrelli, Massimo Ricciutelli, Alessio Paone, Francesca Cutruzzolà, Giorgio Giardina, Serena Rinaldo
Published 2021-01-01

Targeting the Interaction between the SH3 Domain of Grb2 and Gab2

by Francesca Malagrinò, Antonio Coluccia, Marianna Bufano, Giuseppe La Regina, Michela Puxeddu, Angelo Toto, Lorenzo Visconti, Alessio Paone, Maria Chiara Magnifico, Francesca Troilo, Francesca Cutruzzolà, Romano Silvestri, Stefano Gianni
Published 2020-11-01

High-Fat Diet Leads to Reduced Protein O-GlcNAcylation and Mitochondrial Defects Promoting the Development of Alzheimer’s Disease Signatures

by Ilaria Zuliani, Chiara Lanzillotta, Antonella Tramutola, Eugenio Barone, Marzia Perluigi, Serena Rinaldo, Alessio Paone, Francesca Cutruzzolà, Francesco Bellanti, Matteo Spinelli, Francesca Natale, Salvatore Fusco, Claudio Grassi, Fabio Di Domenico
Published 2021-04-01

Metformin Is a Pyridoxal-5′-phosphate (PLP)-Competitive Inhibitor of SHMT2

by Angela Tramonti, Elisabet Cuyàs, José Antonio Encinar, Matthias Pietzke, Alessio Paone, Sara Verdura, Aina Arbusà, Begoña Martin-Castillo, Giorgio Giardina, Jorge Joven, Alexei Vazquez, Roberto Contestabile, Francesca Cutruzzolà, Javier A. Menendez
Published 2021-08-01

Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

by Amani Bouzidi, Maria Chiara Magnifico, Alessandro Paiardini, Alberto Macone, Giovanna Boumis, Giorgio Giardina, Serena Rinaldo, Francesca Romana Liberati, Clotilde Lauro, Cristina Limatola, Chiara Lanzillotta, Antonella Tramutola, Marzia Perluigi, Gianluca Sgarbi, Giancarlo Solaini, Alessandra Baracca, Alessio Paone, Francesca Cutruzzolà
Published 2020-11-01