Epigenetic Modifications and Head and Neck Cancer: Implications for Tumor Progression and Resistance to Therapy

by Rogerio M. Castilho, Cristiane H. Squarize, Luciana O. Almeida
Published 2017-07-01

Profiling the Behavior of Distinct Populations of Head and Neck Cancer Stem Cells

by Luciana O. Almeida, Douglas M. Guimarães, Cristiane H. Squarize, Rogerio M. Castilho
Published 2016-01-01

Accelerated wound healing by mTOR activation in genetically defined mouse models.

by Cristiane H Squarize, Rogerio M Castilho, Thomas H Bugge, J Silvio Gutkind
Published 2010-05-01

Cancer Stem Cells: Powerful Targets to Improve Current Anticancer Therapeutics

by Rayana L. Bighetti-Trevisan, Lucas O. Sousa, Rogerio M. Castilho, Luciana O. Almeida
Published 2019-01-01

Inhibition of histone deacetylase impacts cancer stem cells and induces epithelial-mesenchyme transition of head and neck cancer.

by Fernanda S Giudice, Decio S Pinto, Jacques E Nör, Cristiane H Squarize, Rogerio M Castilho
Published 2013-01-01

Molecular Cross-Talk between the NFκB and STAT3 Signaling Pathways in Head and Neck Squamous Cell Carcinoma

by Cristiane H. Squarize, Rogerio M. Castilho, Virote Sriuranpong, Decio S. Pinto, Jr., Jorge Silvio Gutkind
Published 2006-09-01

Rac1 is required for epithelial stem cell function during dermal and oral mucosal wound healing but not for tissue homeostasis in mice.

by Rogerio M Castilho, Cristiane H Squarize, Kantima Leelahavanichkul, Yi Zheng, Thomas Bugge, J Silvio Gutkind
Published 2010-05-01

PTEN Deficiency Contributes to the Development and Progression of Head and Neck Cancer

by Cristiane H Squarize, Rogerio M Castilho, Aline C Abrahao, Alfredo Molinolo, Mark W Lingen, J Silvio Gutkind
Published 2013-05-01

BMAL1 Modulates Epidermal Healing in a Process Involving the Antioxidative Defense Mechanism

by Ericka J. D. Silveira, Carlos H. V. Nascimento Filho, Veronica Q. Yujra, Liana P. Webber, Rogerio M. Castilho, Cristiane H. Squarize
Published 2020-01-01

PTEN Mediates Activation of Core Clock Protein BMAL1 and Accumulation of Epidermal Stem Cells

by Chiara Zagni, Luciana O. Almeida, Tarek Balan, Marco T. Martins, Luciana K. Rosselli-Murai, Petros Papagerakis, Rogerio M. Castilho, Cristiane H. Squarize
Published 2017-07-01

Skin wound healing triggers epigenetic modifications of histone H4

by Carlos H. V. Nascimento-Filho, Ericka J. D. Silveira, Eny M. Goloni-Bertollo, Lelia Batista de Souza, Cristiane H. Squarize, Rogerio M. Castilho
Published 2020-03-01

NFκB mediates cisplatin resistance through histone modifications in head and neck squamous cell carcinoma (HNSCC)

by Luciana O. Almeida, Aline C. Abrahao, Luciana K. Rosselli-Murai, Fernanda S. Giudice, Chiara Zagni, Andreia M. Leopoldino, Cristiane H. Squarize, Rogerio M. Castilho
Published 2014-01-01

Unlocking the chromatin of adenoid cystic carcinomas using HDAC inhibitors sensitize cancer stem cells to cisplatin and induces tumor senescence

by Luciana O. Almeida, Douglas M. Guimarães, Manoela D. Martins, Marco A.T. Martins, Kristy A. Warner, Jacques E. Nör, Rogerio M. Castilho, Cristiane H. Squarize
Published 2017-05-01

Periostin responds to mechanical stress and tension by activating the MTOR signaling pathway.

by Luciana K Rosselli-Murai, Luciana O Almeida, Chiara Zagni, Pablo Galindo-Moreno, Miguel Padial-Molina, Sarah L Volk, Marcelo J Murai, Hector F Rios, Cristiane H Squarize, Rogerio M Castilho
Published 2013-01-01