AAV-CRB2 protects against vision loss in an inducible CRB1 retinitis pigmentosa mouse model

by Thilo M. Buck, Rogier M. Vos, C. Henrique Alves, Jan Wijnholds
Published 2021-03-01

Microarray and morphological analysis of early postnatal CRB2 mutant retinas on a pure C57BL/6J genetic background.

by Celso Henrique Alves, Koen Bossers, Rogier M Vos, Anke H W Essing, Sigrid Swagemakers, Peter J van der Spek, Joost Verhaagen, Jan Wijnholds
Published 2013-01-01

Specific tools for targeting and expression in Müller glial cells

by Lucie P Pellissier, Robert M Hoek, Rogier M Vos, Wendy M Aartsen, Ryan R Klimczak, Stefan A Hoyng, John G Flannery, Jan Wijnholds
Published 2014-01-01

Defining Phenotype, Tropism, and Retinal Gene Therapy Using Adeno-Associated Viral Vectors (AAVs) in New-Born Brown Norway Rats with a Spontaneous Mutation in <i>Crb1</i>

by Nanda Boon, C. Henrique Alves, Aat A. Mulder, Charlotte A. Andriessen, Thilo M. Buck, Peter M. J. Quinn, Rogier M. Vos, Abraham J. Koster, Carolina R. Jost, Jan Wijnholds
Published 2021-03-01

GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors.

by Wendy M Aartsen, Koen W R van Cleef, Lucie P Pellissier, Robert M Hoek, Rogier M Vos, Bas Blits, Erich M E Ehlert, Kamaljit S Balaggan, Robin R Ali, Joost Verhaagen, Jan Wijnholds
Published 2010-08-01

Transcriptome-wide analysis reveals insight into tumor suppressor functions of 1B3, a novel synthetic miR-193a-3p mimic

by Marion T.J. van den Bosch, Sanaz Yahyanejad, Mir Farshid Alemdehy, Bryony J. Telford, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Marieke Stegink, Laurens A.H. van Pinxteren, Roel Q.J. Schaapveld, Michel Janicot
Published 2021-03-01

Targeted ablation of CRB1 and CRB2 in retinal progenitor cells mimics Leber congenital amaurosis.

by Lucie P Pellissier, Celso Henrique Alves, Peter M Quinn, Rogier M Vos, Naoyuki Tanimoto, Ditte M S Lundvig, Jacobus J Dudok, Berend Hooibrink, Fabrice Richard, Susanne C Beck, Gesine Huber, Vithiyanjali Sothilingam, Marina Garcia Garrido, André Le Bivic, Mathias W Seeliger, Jan Wijnholds
Published 2013-01-01

Human iPSC-Derived Retinas Recapitulate the Fetal CRB1 CRB2 Complex Formation and Demonstrate that Photoreceptors and Müller Glia Are Targets of AAV5

by Peter M. Quinn, Thilo M. Buck, Aat A. Mulder, Charlotte Ohonin, C. Henrique Alves, Rogier M. Vos, Monika Bialecka, Tessa van Herwaarden, Elon H.C. van Dijk, Mays Talib, Christian Freund, Harald M.M. Mikkers, Rob C. Hoeben, Marie-José Goumans, Camiel J.F. Boon, Abraham J. Koster, Susana M. Chuva de Sousa Lopes, Carolina R. Jost, Jan Wijnholds
Published 2019-05-01