Post-translational Mechanisms Regulating NK Cell Activating Receptors and Their Ligands in Cancer: Potential Targets for Therapeutic Intervention

by Rosa Molfetta, Alessandra Zingoni, Angela Santoni, Rossella Paolini
Published 2019-10-01

Ubiquitin and ubiquitin-like modifiers modulate NK cell-mediated recognition and killing of damaged cells

by Rosa Molfetta, Beatrice Zitti, Angela Santoni, Rossella Paolini
Published 2017-11-01

Regulation of NKG2D-Dependent NK Cell Functions: The Yin and the Yang of Receptor Endocytosis

by Rosa Molfetta, Linda Quatrini, Angela Santoni, Rossella Paolini
Published 2017-08-01

FcεRI Signaling in the Modulation of Allergic Response: Role of Mast Cell-Derived Exosomes

by Mario Lecce, Rosa Molfetta, Nadia Domenica Milito, Angela Santoni, Rossella Paolini
Published 2020-07-01

Lipid raft-dependent FcepsilonRI ubiquitination regulates receptor endocytosis through the action of ubiquitin binding adaptors.

by Rosa Molfetta, Francesca Gasparrini, Giovanna Peruzzi, Laura Vian, Mario Piccoli, Luigi Frati, Angela Santoni, Rossella Paolini
Published 2009-01-01

NKG2D and Its Ligands: “One for All, All for One”

by Alessandra Zingoni, Rosa Molfetta, Cinzia Fionda, Alessandra Soriani, Rossella Paolini, Marco Cippitelli, Cristina Cerboni, Angela Santoni
Published 2018-03-01

Obinutuzumab-mediated high-affinity ligation of FcγRIIIA/CD16 primes NK cells for IFNγ production

by Cristina Capuano, Chiara Pighi, Rosa Molfetta, Rossella Paolini, Simone Battella, Gabriella Palmieri, Giuseppe Giannini, Francesca Belardinilli, Angela Santoni, Ricciarda Galandrini
Published 2017-03-01

CD155: A Multi-Functional Molecule in Tumor Progression

by Rosa Molfetta, Beatrice Zitti, Mario Lecce, Nadia Domenica Milito, Helena Stabile, Cinzia Fionda, Marco Cippitelli, Angela Gismondi, Angela Santoni, Rossella Paolini
Published 2020-01-01

Immunomodulatory effect of NEDD8-activating enzyme inhibition in Multiple Myeloma: upregulation of NKG2D ligands and sensitization to Natural Killer cell recognition

by Sara Petillo, Cristina Capuano, Rosa Molfetta, Cinzia Fionda, Abdelilah Mekhloufi, Chiara Pighi, Fabrizio Antonangeli, Alessandra Zingoni, Alessandra Soriani, Maria Teresa Petrucci, Ricciarda Galandrini, Rossella Paolini, Angela Santoni, Marco Cippitelli
Published 2021-09-01

Inhibition of bromodomain and extra-terminal (BET) proteins increases NKG2D ligand MICA expression and sensitivity to NK cell-mediated cytotoxicity in multiple myeloma cells: role...

by Maria Pia Abruzzese, Maria Teresa Bilotta, Cinzia Fionda, Alessandra Zingoni, Alessandra Soriani, Elisabetta Vulpis, Cristiana Borrelli, Beatrice Zitti, Maria Teresa Petrucci, Maria Rosaria Ricciardi, Rosa Molfetta, Rossella Paolini, Angela Santoni, Marco Cippitelli
Published 2016-12-01

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

by Abdelilah Mekhloufi, Andrea Kosta, Helena Stabile, Rosa Molfetta, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Rossella Paolini, Angela Gismondi, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Laura Masuelli, Giulio Caracciolo, Sara Palchetti, Angela Santoni, Cinzia Fionda
Published 2020-02-01

Genotoxic stress modulates the release of exosomes from multiple myeloma cells capable of activating NK cell cytokine production: Role of HSP70/TLR2/NF-kB axis

by Elisabetta Vulpis, Francesca Cecere, Rosa Molfetta, Alessandra Soriani, Cinzia Fionda, Giovanna Peruzzi, Giulio Caracciolo, Sara Palchetti, Laura Masuelli, Lucilla Simonelli, Ugo D'Oro, Maria Pia Abruzzese, Maria Teresa Petrucci, Maria Rosaria Ricciardi, Rossella Paolini, Marco Cippitelli, Angela Santoni, Alessandra Zingoni
Published 2017-03-01

3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells

by Stefania Parlato, Adele De Ninno, Rosa Molfetta, Elena Toschi, Debora Salerno, Arianna Mencattini, Giulia Romagnoli, Alessandra Fragale, Lorenzo Roccazzello, Maria Buoncervello, Irene Canini, Enrico Bentivegna, Mario Falchi, Francesca Romana Bertani, Annamaria Gerardino, Eugenio Martinelli, Corrado Natale, Rossella Paolini, Luca Businaro, Lucia Gabriele
Published 2017-04-01

SAMHD1 phosphorylation and cytoplasmic relocalization after human cytomegalovirus infection limits its antiviral activity.

by Simone De Meo, Valentina Dell'Oste, Rosa Molfetta, Valentina Tassinari, Lavinia Vittoria Lotti, Simone Vespa, Benedetta Pignoloni, Daniela Angela Covino, Laura Fantuzzi, Roberta Bona, Alessandra Zingoni, Ilaria Nardone, Matteo Biolatti, Alessandra Coscia, Rossella Paolini, Monsef Benkirane, Fredrik Edfors, Tatyana Sandalova, Adnane Achour, John Hiscott, Santo Landolfo, Angela Santoni, Cristina Cerboni
Published 2020-09-01