Human fetal liver cells for regulated ex vivo erythropoietin gene therapy

by Ebtisam El Filali, Suzanne Duijst, Johan K Hiralall, Nicolas Legrand, Thomas van Gulik, Ruurdtje Hoekstra, Jurgen Seppen
Published 2014-01-01

A practice-changing culture method relying on shaking substantially increases mitochondrial energy metabolism and functionality of human liver cell lines.

by Aziza A A Adam, Vincent A van der Mark, Joanne M Donkers, Manon E Wildenberg, Ronald P J Oude Elferink, Robert A F M Chamuleau, Ruurdtje Hoekstra
Published 2018-01-01

In Vitro Functionality of Human Fetal Liver Cells and Clonal Derivatives under Proliferative Conditions

by Tanja Deurholt, Lysbeth Ten Bloemendaal, Aniska A. Chhatta, Albert C. W. A. Van Wijk, Kees Weijer, Jurgen Seppen, Ronald P. J. Oude Elferink, Robert A. F. M. Chamuleau, Ruurdtje Hoekstra
Published 2006-09-01

Assessment of in Vitro Applicability of Reversibly Immortalized NKNT-3 Cells and Clonal Derivatives

by Ruurdtje Hoekstra, Tanja Deurholt, Lysbeth ten Bloemendaal, Mireille Desille, Albert C. W. A. van Wijk, Bruno Clement, Ronald P. J. Oude Elferink, Thomas M. van Gulik, Robert A. F. M. Chamuleau
Published 2006-05-01

HepaRG-Progenitor Cell Derived Hepatocytes Cultured in Bioartificial Livers Are Protected from Healthy- and Acute Liver Failure-Plasma Induced Toxicity

by Martien van Wenum, Philipp Treskes, Aziza A.A. Adam, Vincent. A van der Mark, Aldo Jongejan, Perry D. Moerland, Thomas M. van Gulik, Ronald P.J. Oude Elferink, Robert A.F.M. Chamuleau, Ruurdtje Hoekstra
Published 2018-08-01

Liver progenitor cell line HepaRG differentiated in a bioartificial liver effectively supplies liver support to rats with acute liver failure.

by Geert A A Nibourg, Robert A F M Chamuleau, Tessa V van der Hoeven, Martinus A W Maas, An F C Ruiter, Wouter H Lamers, Ronald P J Oude Elferink, Thomas M van Gulik, Ruurdtje Hoekstra
Published 2012-01-01