Human fetal liver cells for regulated ex vivo erythropoietin gene therapy

by Ebtisam El Filali, Suzanne Duijst, Johan K Hiralall, Nicolas Legrand, Thomas van Gulik, Ruurdtje Hoekstra, Jurgen Seppen
Published 2014-01-01

Nafamostat–Interferon-α Combination Suppresses SARS-CoV-2 Infection In Vitro and In Vivo by Cooperatively Targeting Host TMPRSS2

by Aleksandr Ianevski, Rouan Yao, Hilde Lysvand, Gunnveig Grødeland, Nicolas Legrand, Valentyn Oksenych, Eva Zusinaite, Tanel Tenson, Magnar Bjørås, Denis E. Kainov
Published 2021-09-01

Preclinical In Vivo Evaluation of the Safety of a Multi-shRNA-based Gene Therapy Against HIV-1

by Mireille Centlivre, Nicolas Legrand, Sofieke Klamer, Ying Poi Liu, Karin Jasmijn von Eije, Martino Bohne, Esther Siteur-van Rijnstra, Kees Weijer, Bianca Blom, Carlijn Voermans, Hergen Spits, Ben Berkhout
Published 2013-01-01

A novel mouse model for stable engraftment of a human immune system and human hepatocytes.

by Helene Strick-Marchand, Mathilde Dusséaux, Sylvie Darche, Nicholas D Huntington, Nicolas Legrand, Guillemette Masse-Ranson, Erwan Corcuff, James Ahodantin, Kees Weijer, Hergen Spits, Dina Kremsdorf, James P Di Santo
Published 2015-01-01

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice.

by Pablo D Becker, Nicolas Legrand, Caroline M M van Geelen, Miriam Noerder, Nicholas D Huntington, Annick Lim, Etsuko Yasuda, Sean A Diehl, Ferenc A Scheeren, Michael Ott, Kees Weijer, Heiner Wedemeyer, James P Di Santo, Tim Beaumont, Carlos A Guzman, Hergen Spits
Published 2010-10-01