Antigen-specific monoclonal antibodies isolated from B cells expressing constitutively active STAT5.

by Ferenc A Scheeren, Caroline M M van Geelen, Etsuko Yasuda, Hergen Spits, Tim Beaumont
Published 2011-01-01

Multiple capsid-stabilizing interactions revealed in a high-resolution structure of an emerging picornavirus causing neonatal sepsis

by Shabih Shakeel, Brenda M. Westerhuis, Ausra Domanska, Roman I. Koning, Rishi Matadeen, Abraham J. Koster, Arjen Q. Bakker, Tim Beaumont, Katja C. Wolthers, Sarah J. Butcher
Published 2016-07-01

499 AT1636, a colon cancer survivor-derived antibody recognizes a previously unidentified truncated, O-mannosylated 70kDa variant of E-cadherin

by Evelien Dekker, Tim Beaumont, Sabrina Merat, Mark Kwakkenbos, Lina Bartels, Dorien van der Berg, Koen Wagner, Arjen Bakker, Kelly Maijoor, Martino Bohne, Camille Bru, Veronika Kattler, Yvonne Claassen, Victorine Roos, Frank Kallenberg, Jan Medema, Paul Hensbergen
Published 2020-11-01

Characterization of a Prefusion-Specific Antibody That Recognizes a Quaternary, Cleavage-Dependent Epitope on the RSV Fusion Glycoprotein.

by Morgan S A Gilman, Syed M Moin, Vicente Mas, Man Chen, Nita K Patel, Kari Kramer, Qing Zhu, Stephanie C Kabeche, Azad Kumar, Concepción Palomo, Tim Beaumont, Ulrich Baxa, Nancy D Ulbrandt, José A Melero, Barney S Graham, Jason S McLellan
Published 2015-07-01

Hepatitis C virus Broadly Neutralizing Monoclonal Antibodies Isolated 25 Years after Spontaneous Clearance.

by Sabrina J Merat, Richard Molenkamp, Koen Wagner, Sylvie M Koekkoek, Dorien van de Berg, Etsuko Yasuda, Martino Böhne, Yvonne B Claassen, Bart P Grady, Maria Prins, Arjen Q Bakker, Menno D de Jong, Hergen Spits, Janke Schinkel, Tim Beaumont
Published 2016-01-01

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice.

by Pablo D Becker, Nicolas Legrand, Caroline M M van Geelen, Miriam Noerder, Nicholas D Huntington, Annick Lim, Etsuko Yasuda, Sean A Diehl, Ferenc A Scheeren, Michael Ott, Kees Weijer, Heiner Wedemeyer, James P Di Santo, Tim Beaumont, Carlos A Guzman, Hergen Spits
Published 2010-10-01

Novel staphylococcal glycosyltransferases SdgA and SdgB mediate immunogenicity and protection of virulence-associated cell wall proteins.

by Wouter L W Hazenbos, Kimberly K Kajihara, Richard Vandlen, J Hiroshi Morisaki, Sophie M Lehar, Mark J Kwakkenbos, Tim Beaumont, Arjen Q Bakker, Qui Phung, Lee R Swem, Satish Ramakrishnan, Janice Kim, Min Xu, Ishita M Shah, Binh An Diep, Tao Sai, Andrew Sebrell, Yana Khalfin, Angela Oh, Chris Koth, S Jack Lin, Byoung-Chul Lee, Magnus Strandh, Klaus Koefoed, Peter S Andersen, Hergen Spits, Eric J Brown, Man-Wah Tan, Sanjeev Mariathasan
Published 2013-01-01