The synthetic progestin norgestrel modulates Nrf2 signaling and acts as an antioxidant in a model of retinal degeneration

by Ashleigh M. Byrne, Ana M. Ruiz-Lopez, Sarah L. Roche, Jennifer N. Moloney, Alice C. Wyse -Jackson, Thomas G. Cotter
Published 2016-12-01

Total protein analysis as a reliable loading control for quantitative fluorescent Western blotting.

by Samantha L Eaton, Sarah L Roche, Maica Llavero Hurtado, Karla J Oldknow, Colin Farquharson, Thomas H Gillingwater, Thomas M Wishart
Published 2013-01-01

Progesterone Attenuates Microglial-Driven Retinal Degeneration and Stimulates Protective Fractalkine-CX3CR1 Signaling.

by Sarah L Roche, Alice C Wyse-Jackson, Violeta Gómez-Vicente, Pedro Lax, Ana M Ruiz-Lopez, Ashleigh M Byrne, Nicolás Cuenca, Thomas G Cotter
Published 2016-01-01

Selective Histone Deacetylase 6 Inhibitors Restore Cone Photoreceptor Vision or Outer Segment Morphology in Zebrafish and Mouse Models of Retinal Blindness

by Husvinee Sundaramurthi, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Husvinee Sundaramurthi, Sarah L. Roche, Guinevere L. Grice, Ailis Moran, Ailis Moran, Eugene T. Dillion, Eugene T. Dillion, Giuseppe Campiani, James A. Nathan, Breandán N. Kennedy, Breandán N. Kennedy
Published 2020-08-01

A novel mouse model of Warburg Micro syndrome reveals roles for RAB18 in eye development and organisation of the neuronal cytoskeleton

by Sarah M. Carpanini, Lisa McKie, Derek Thomson, Ann K. Wright, Sarah L. Gordon, Sarah L. Roche, Mark T. Handley, Harris Morrison, David Brownstein, Thomas M. Wishart, Michael A. Cousin, Thomas H. Gillingwater, Irene A. Aligianis, Ian J. Jackson
Published 2014-06-01